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Arnold I. Chin, MD, PhD

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Arnold Chin, MD, PhD

UCLA Physician Arnold Chin, MD, PhD specializes in Urology.
Preferred Name
Arnold I. Chin
Specialty
Urology
Gender
Male
Language Spoken
English, Mandarin
Hospital Affiliation
Ronald Reagan UCLA Medical Center
State License Number
A89934
Contact
(310) 794-7700 Information and referral
(310) 206-6453
Fax Number
(310) 206-1265
Email Address
aichin@ucla.edu
PRACTICE LOCATION

Clark Urological Center
Peter Morton Medical Building
200 UCLA Medical Plaza, Suite 140
Los Angeles, CA 90095

MEDICAL BOARD CERTIFICATION
Urology, American Board of Urology, 2011
EDUCATION
Residency
Urology, UCLA School of Medicine, 2004 - 2009
Internship
Surgery, UCLA School of Medicine, 2003 - 2004
Degree
MD, UCLA School of Medicine, 2003
CLINICAL INTEREST
Bladder Cancer, Hematuria, Prostatitis, Robotic Surgery-Bladder, Urinary Tract Infection (Male)
AFFILIATION
IN THE NEWS
MORE INFORMATION
Research Interest
My clinical expertise includes urologic oncology and renal transplantation, performing open, laparoscopic, and robotic-assisted surgeries for bladder, kidney, and prostate cancer patients.

Our laboratory studies the tumor microenvironment in prostate and bladder cancer using a combination of animal models, human reconstitution systems, and primary tumor and hematopoietic cells. We are interested in several aspects including the following:

1. Molecular mechanisms in programing tumor-infiltrating lymphocytes. The nature and composition of immune cells in cancer have been linked with tumor grade and overall survival. However, the determinants that lead to immune infiltrating cells in cancer is unclear. We are studying the endogenous signals, innate immune, and adaptive immune pathways that program the composition of the tumor immune microenvironment, and how these will influence tumor proliferation, invasion, and metastasis. We are also interested in how we can reprogram the immune components of the tumor microenvironment to shape tumorigenicity.

2. Mechanisms controlling development and differentiation of cancer stem cells. Cancer initiating cells share similar features to stem cells with their ability for self-renewal and pluripotency. These cell populations may explain the recurrent nature and drug resistance of cancer. We are studying the cell intrinsic signals as well as the cell extrinsic influences from immune and stromal cells of the cancer stem cell in their differentiation, ability to undergo epithelial-to-mesenchymal transition, and development of an invasive phenotype.

Our studies will provide fundamental understanding of the tumor microenvironment, as well as develop therapeutic targets, novel immune-based platforms, and stem cell based therapies against cancer.

Additional Information

Education/Certification

  • PhD, UCLA, 2002

Professional Memberships

  • American Urological Association
  • American Association of Cancer Research
  • Society of Urology Oncology

Academic & Medical Staff Appointments

  • Assistant Professor Department of Urology, UCLA School of Medicine 2009
  • Broad Stem Cell Research Center 2009
  • Tumor Immunology Program Area of the Jonsson Comprehensive Cancer Center 2009
  • Genitourinary Oncology Program Area of the Jonsson Comprehensive Cancer Center 2009

Patient Education (PDFs)

Awards & Recognition
  • STOP Cancer Research Career Development Award 2010
  • American Association of Cancer Research Career Development Award for Translational Cancer Research 2010
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