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Clinical Trials at UCLA

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Information for Participants (UCLA OHRPP)
Understanding Clinical Trials (ClinicalTrials.gov)
UCLA Cancer Trials (UCLA JCCC)
Link to Non-Cancer Trials at UCLA
 

Research and Clinical Trials

UCLA conducts research for a wide range of medical disorders and offers patients opportunities to participate in research and clinical trials.

Visit our Office of Clinical Trials website for more information about clinical trials.

Below are some featured trials at UCLA. Click here for a PDF of these trials. You may also visit the links to the right for additional trials from our clinical departments.

 


Treatment Study for ADHD, Irritability and Mood Disregulation

The Division of Child and Adolescent Psychiatry at UCLA is recruiting participants for a research study of children and teens with a newly recognized condition called Severe Mood Dysregulation (SMD).   SMD is characterized by persistent irritability or moodiness, overarousal (including insomnia, agitation, distractibility, racing thoughts, pressured speech, or intrusiveness), and frequent temper tantrums, emotional "meltdowns," or aggression.  Participants in the study will receive a comprehensive evaluation.  Individuals found to be eligible will also be invited to participate in a medication study that includes treatment with an ADHD medication and either fluoxetine or placebo.  All evaluations and medications will be provided without charge.
INFO: (310) 825-6170 or adhdandmood@ucla.edu

Aftercare Research

The Aftercare Research at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA provides free treatment and assessments for participants in a clinical research study that is designed to improve the understanding of psychotic disorders and to develop more effective treatments. An initial diagnostic interview will determine a patient’s eligibility. The study will include individual case management, group therapy, and the antipsychotic medication risperidone. Family members of patients will be invited to join family psychoeducational meetings. An initial period on risperidone is a requirement of this study, so a change of medication may be needed.
INFO: (310) 206-3142 or Aftercare@mednet.ucla.edu , luana@ucla.edu

UCLA Down Syndrome and Alzheimer's Disease Study

The UCLA Longevity Center is currently enrolling adults with Down syndrome (DS) ages 40 and older to study the correlation between DS and Alzheimer's disease. Study procedures will include a memory assessment, a neurological evaluation, a blood draw, an MRI, and two PET scans over three to four visits. Subjects will be compensated for participation and receive clinically relevant results of assessments.
INFO: (310) 206-7392 or (310) 825-0545

Child Anxiety Study

This UCLA Research Study conducted by Susanna Chang, PhD, is investigating the usefulness of a novel computer-based attention training treatment for childhood anxiety. We are seeking help from children ages 8 to 17 with social anxiety, generalized anxiety and separation anxiety, and their parents. Participation involves EEG recordings and eight weeks of a non-medication attention training treatment for children. Parents of eligible study youth are also asked to participate in similar attention training treatment to study how their participation may improve their child’s anxiety.
INFO: (310) 825-2064

Child Obsessive Compulsive Disorder Study

This UCLA research study conducted by Susanna Chang, PhD, is investigating the usefulness of a novel computer-based attention training treatment for childhood OCD. We are seeking help from children ages 8 to 17 with OCD as study participants. Participation involves EEG recordings and four weeks of a non-medication attention training treatment.
INFO: (310) 206-1350

Dental Implant Screening

You're invited to learn about this alternative to dentures by making an appointment for a dental implant screening. By appointment only. Monday through Friday 9:00 a.m. to noon and 1:00 p.m. to 4:00 p.m. 
WHERE:
Straumann Surgical Dental Clinic, UCLA School of Dentistry, B-level, 10833 Le Conte Avenue, Los Angeles.
INFO: (310) 206-2290

Late-life Depression

For those who are suffering from feelings of depression, sadness, hopelessness, memory loss, concentration difficulties, lack of energy, or loss of interest and pleasure in activities, UCLA is conducting a 12-month research study using an experimental combination of two drugs and a placebo (an inactive substance). If you are 60 years of age or older and not currently receiving any psychiatric treatment with effective medications, you may qualify. Medical and psychiatric evaluations and limited physical exams are provided as a part of the study. Participants will undergo a PET scan and MRI scan. Evaluations and study drug are provided at no charge.
INFO: (310) 983-3375 or (310) 794-4619

Senior Depression Study

The UCLA Geriatric Psychiatry Program is conducting an early phase 12-week research study to compare the effects of two FDA-approved medications — vilazodone and paroxetine — for the treatment of geriatric depression. This study is for those who are suffering from feelings of depression, sadness, hopelessness, memory loss, concentration difficulties, lack of energy, or loss of interest and pleasure in activities. All participants will be given the study drug, either vilazodone or paroxetine. A complete psychiatric evaluation will be provided. Subjects will not be charged for participation and will be compensated. Participants must be 60 years or older and experiencing symptoms of depression.
Info: (310) 983-3375 or (310) 794-4619

Developmental Pathways of Internalizing Disorders Study

This UCLA research study, conducted by Cara Kiff, PhD, investigates how stress at home, school and in children’s neighborhoods might lead some children to develop anxiety and/or depression and how children’s physiology responds to stress. We are seeking help from children ages 10 to 14 and their mothers. Participation includes a one-time visit to the UCLA campus.
Info: (310) 825-2064 or anxietyinfo@ucla.edu

Dietary Supplement Research on Memory

This project is designed to study the effects of the dietary supplement curcumin on cognitive impairment. In particular, the study will determine the effects of curcumin on cognitive decline and on the amount of abnormal amyloid protein in the brain. People with memory complaints ages 50 to 90 are encouraged to participate. This study involves eight visits over the course of 18 months. Subjects will be compensated for participation and receive clinically relevant results of assessments.
INFO: (310) 825-0545

Fat Metabolism in Women Study

UCLA OB/GYN researchers are seeking participants for a research study to learn more about fat metabolism in women. The eligibility criteria include all of the following: Caucasian Non-Hispanic women, ages 18 to 35 years, irregular menstrual periods (<21 days or >35 days apart), excessive body hair on lip, chin, chest and/or abdomen, Body Mass Index (BMI) between 18.5 and 25, and no hormone use (i.e., birth control pills or a Mirena IUD) within three months. All participants in the study will receive extensive free medical testing including: a test for glucose metabolism (frequently-sampled intravenous glucose tolerance test) ultrasound of ovaries to check for cysts and follicles, a test of ovarian hormone secretions (Follicle-Stimulating Hormone Stimulation Test), MRI and DXA scans to determine the distribution of body fat, removal of a small amount of abdominal fat, laboratory tests and physical exams. Participants will take an oral pill that contains either the drug Flutamide or a placebo (sugar pill) for six complete 28 day cycles. Study procedures will be repeated after the six-month period, at the end of the study. Participants may earn up to $840.
INFO: (310) 825-5255 or uclaobgynresearch@mednet.ucla.edu

Fibroid Research

Do you have fibroids? Researchers are looking for women, ages 18 and older, with fibroids causing heavy bleeding, pelvic pressure or other symptoms to participate in a study using FDA approved radiofrequency energy to destroy fibroid cells. Earn up to $180 for participating.
INFO: (310) 825-5255 or uclaobgynresearch@mednet.ucla.edu

Study on Fitness and Memory

This project is designed to study the relationship between physical fitness, memory and the brain. People with memory complaints ages 60 to 89 are encouraged to participate. This study involves cognitive evaluations, brain MRIs and wearing activity monitors four times over the course of 18 months. Subjects will be compensated for participation and receive clinically relevant results of assessments.
INFO: (310) 206-7392

Irritable Bowel Syndrome

Are diarrhea and abdominal discomfort changing the way you see the world? Diarrhea, abdominal discomfort and bloating may be signs of irritable bowel syndrome (IBS). If you have IBS, you may be eligible for a UCLA clinical research study testing an investigational medication for treatment of IBS.

If you qualify for this study, you may receive an investigational medication for IBS, study-related care from a local doctor, and compensation for your time and travel. To qualify you must have been experiencing diarrhea, abdominal discomfort and bloating on and off in the last three months and/or have been previously diagnosed with IBS with diarrhea, have had trouble getting relief for your symptoms and be at least 18 years old.
INFO: (310) 206-1719

Maternal Anxiety Study

Mothers, do you worry more than others? Often feel stressed, anxious or scared? Feel so nervous or shy that it gets in the way of work or relationships? If you answered “yes” to any of these questions, you and your child may be eligible to participate in a study about how anxiety affects families. To be eligible, mothers must have a child 8 to 15 years of age, live with the child for past six months, and be able to complete questionnaires in English or Spanish. Mothers and children can earn $80 for participating in a onevisit study at UCLA. You and your child are asked to complete questionnaires, and to complete a few tasks together while we collect information about your child’s heart rate and breathing. Interested families may be provided with clinical referrals.
INFO: (310) 825-2701

Memory Enhancement Training or Yoga for Older Adults

For those who are suffering from memory loss, concentration difficulties, or lack of energy, UCLA is conducting a six-month research study comparing a 60-minute weekly memory enhancement training course to yoga meditation. If you are 55 years of age or older and not currently receiving any psychiatric treatment, you may qualify. Medical and psychiatric evaluations and limited physical exams are provided as a part of the study. Participants will undergo two functional magnetic resonance imaging (fMRI) scans. A complete psychiatric evaluation will be provided. Participants will be compensated.
INFO: (310) 983-3375 or (310) 794-4619

Menstrual Irregularities and PCOS Study

UCLA researchers are seeking women with irregular menstrual periods (<21 or >35 days apart) and excessive  body hair on lip, chin, chest, and/or abdomen.  Participants must be Non-Hispanic Caucasian; between the ages of 18 and 35; lean body mass index (BMI) between 18.5 and 25 kg/m2; and have not used prescription hormones, such as birth control pills, for at least three months.  Participants receive free extensive medical testing and may earn up to $840. In order to protect your privacy, please do not include any personal health information if you choose to contact us by email.  
INFO: (310) 825-5255 or uclaobgynresearch@mednet.ucla.edu  

Family Focused Treatment for Childhood OCD

Does your child have Obsessive Compulsive Disorder (OCD)? Does he/she: Have recurring thoughts that make no sense, but makes him/ her feel bad? Wash excessively or have fear of touching “contaminated” things? Check and double-check more than necessary? Have to do things over and over again? A UCLA research study for kids and teens 8 to 17 with OCD is studying family involvement in non-medication Cognitive-Behavioral Therapy. Eligible participants will receive 14 weeks free treatment with Cognitive-Behavioral Therapy.
INFO: (310) 206-1350

Pomegranate Research

The UCLA Longevity Center is researching pomegranate extract to determine whether it benefits cognitive abilities in healthy older adults, ages 50 to 75. This study involves seven visits to UCLA over the course of 12-13 months. Subjects will be compensated for participation and receive clinically relevant results of assessments.
INFO: (310) 206-1319

Premenstrual Dysphoric Disorder Research Study

If you have moderate to severe mood symptoms that only occur before your menstrual period, you may be eligible for a UCLA research study of the neurobiological basis of Premenstrual Dysphoric Disorder (PMDD). If you have no premenstrual symptoms, you could be a control participant.Must be healthy, age 18-44, not on hormonal contraceptives or PMDD treatment, and right handed. Earn $335 if you qualify and complete the study.
INFO: (888) 791-9988 or ucla.pmdd@gmail.com

Research Study Volunteer Project

RSVP (Research Study Volunteer Project) is a UCLA program that matches volunteers with research studies. RSVP can match men and women and transgender men and women with studies based on the answers you give during the online registration process. While our primary focus is for HIV-related studies, we are looking for both HIV positive and HIV negative volunteers. We also are looking for men and women for hepatitis studies.
INFO: hivrsvp.ucla.edu or call (310) 557-3743

Vulvar Pain Research

Do you have vulvar pain with or without intercourse? We are looking for females between ages 18 and 55 with chronic pain at the opening of the vagina or at the area surrounding the opening. Earn up to $130. The study involves two visits (one screening, one MRI scan). Participants must be right handed and not pregnant.
INFO: (310) 825-5255 or  smasghati@mednet.ucla.edu

 


For more information about Clinical Trials offered to cancer patients, visit:
www.cancer.ucla.edu/clinical-trials or call UCLA jonsson Comprehensive Cancer Center (JCCC) Clinical Trials Hotline at (888) 798-0719.