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Clinical Trials at UCLA


Helpful Links

Information for Participants (UCLA OHRPP)
Understanding Clinical Trials (ClinicalTrials.gov)
UCLA Cancer Trials (UCLA JCCC)
Link to Non-Cancer Trials at UCLA

Research and Clinical Trials

UCLA conducts research for a wide range of medical disorders and offers patients opportunities to participate in research and clinical trials.

Visit our Office of Clinical Trials website for more information about clinical trials.

Below are some featured trials at UCLA. Click here for a PDF of these trials. You may also visit the links to the right for additional trials from our clinical departments.

UCLA Aftercare Research Program

The Aftercare Research Program at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA will provide free treatment and assessment for participants in a clinical research study that is designed to improve the understanding of psychotic disorders and to develop more effective treatments. An initial diagnostic interview will determine a patient's eligibility. The study will include individual case management, group therapy, and the antipsychotic medication risperidone. Family members of patients will be invited to join family psychoeducational meetings. An initial period on risperidone is a requirement of this study, so a change of medication may be needed.
Info: aftercare@mednet.ucla.edu, luana@ucla.edu or (310) 206-3142

UCLA Baby Foods Research Study

Mothers and their non-breastfed infants are invited to participate in a UCLA research study on different baby foods. This study will measure iodine levels in infant foods and baby's urine. It is a single study visit with no blood or other samples needed. You will be paid $40 for your participation. You may be eligible if you have a baby less than 1 year old, the baby was born full-term, not being breastfed and at least 18 years old.
Info: babyfood@mednet.ucla.edu or (310) 478-3711 (ext 49088)

The Brain - The Gut - The Microbiome

Have you been diagnosed with Irritable Bowel Syndrome or Ulcerative Collitis? Join us in Brain Imaging Research conducted by Emeran Mayer, MD, PhD, UCLA Gail and Gerald Oppenheimer Family Center for Neurobiology of Stress, for a study to identify biomarkers of chronic pain. You must be 18 to 55 years of age, right-handed, not pregnant or post-menopausal, with no significant neurological or psychological medical history. Earn up to $125 and receive a digital picture of your brain.
Info: (310) 206-1758 or uclacns.org

A Woman's Own Words: Decisions About Hormonal Treatment After Breast Cancer

Women 65 years of age or older, who take or have taken hormonal treatment within the past 6 to 18 months are needed to participate in a research study to be interviewed about her experience with continuing or stopping a hormonal treatment such as Arimidex®, Aromasin® or Femara®. Participants will be interviewed for one to one-and-a- half hours by Huibrie Pieters, PhD, DPhil, RN. Receive $60 for your participation.
Info: (424)-241-0149

Child Anxiety Study

Conducted by Susanna Chang, MD, this UCLA study is investigating the usefulness of a novel computer-based attention-training treatment for childhood anxiety. We are seeking help from children (ages 8 to¬ 17) with social anxiety, generalized anxiety, and separation anxiety and their parents. Participation involves EEG recordings and eight weeks of a non-medication attention-training treatment for children. Parents of eligible participants will be asked to participate in a similar attention-training treatment to study how their participation may improve their child's anxiety.
Info: (310) 825-2064

Cognitive Physiological Correlates of Anxiety in Youth

If you have a child between the ages of 9 and 17 years, he/she is invited to take part in a free research study at UCLA. Participants must be healthy, speak English and currently living with their legal guardian.

Participants will undergo a psychological evaluation, fulfill two computer tasks and two problem-solving tasks to see how he/she perceives and thinks about the world, and have his/her heart rate and breathing monitored. The study takes approximately three hours and requires one visit to UCLA. Please note that the study does not provide transportation to/from or parking at UCLA. This study is conducted by Michelle Rozenman, PhD, and John Piacentini, PhD, at the UCLA Semel Institute for Neuroscience & Human Behavior.
Info: (310) 794-2215

Maternal Anxiety Study

Mothers, do you worry more than others? Often feel stressed, anxious or scared? Feel so nervous or shy that it gets in the way of work or relationships? If you answered "yes" to any of these questions, you and your child may be eligible to participate in a study about how anxiety affects families. To be eligible, mothers must have a child 8 to 15 years of age, live with child for past six months, be able to complete questionnaires in English or Spanish. Mothers and children can earn $80 for participating in a one-visit study at UCLA. You and your child will be asked to complete questionnaires and to complete a few tasks together while we collect information about your child's heart rate and breathing. Interested families may be provided with clinical referrals.
Info: (310) 825-2701

Caregiver Depression Meditation Study

Do you care for a family member with dementia? Do you have low mood or difficulty getting pleasure out of life? We are conducting a study of a mindfulness meditation and guided-imagery therapy for caregivers who suffer from symptoms of depression such as (but not limited to) low mood, difficulty sleeping, and reduced interest in activities. The research study includes four weekly visits to UCLA for group meditation therapy, as well as two to three visits to measure brain activity and obtain a blood sample. If applicable, participants may not change antidepressants or therapy for up to 16 weeks. Reimbursement is available for the brain activity recordings and blood draws up to $250 in addition to parking.
Info: (310) 825-3351 or depressionla.com

Geriatric Depression

The UCLA Geriatric Psychiatry Program is conducting an early phase 12-week research study to compare the effects of two FDA-approved medications: Vilazodone and Paroxetine for the treatment of geriatric depression. This study is for those who are suffering from feelings of depression, sadness, hopelessness, memory loss, concentration difficulties, lack of energy, or loss of interest and pleasure in activities. All participants will be given the study drug, either Vilazodone or Paroxetine. A complete psychiatric evaluation will be provided. Subjects will not be charged for participation and will be compensated. Participants must be 60 years or older and experiencing symptoms of depression.
Info: (310) 983-3375 or (310) 794-4619

Late-life Depression

For those who are suffering from feelings of depression, sadness, hopelessness, memory loss, concentration difficulties, lack of energy, or loss of interest and pleasure in activities, UCLA is conducting a 12-month research study using an experimental combination of two drugs and a placebo (an inactive substance). If you are 60 years of age or older, not currently receiving any psychiatric treatment with effective medications, you may qualify. Medical and psychiatric evaluations and limited physical exams are provided as a part of the study. Participants will undergo a PET scan and an MRI scan. Evaluations and study drug are provided at no charge.
Info: (310) 983-3375 or (310) 794-4619

Study on Fitness and Memory

This project is designed to study the relationship between physical fitness, memory and the brain. People with memory complaints ages 60 to 89 are encouraged to participate. This study involves cognitive evaluations, brain MRIs and wearing activity monitors four times over the course of 18 months. Subjects will be compensated for participation and receive clinically relevant results of assessments.
Info: (310) 206-7392

Japanese Herbal Study for Women with Irritable Bowel Syndrome and Bloating

Do you suffer from chronic abdominal pain, discomfort and bloating? Do you experience diarrhea or constipation, or even both? You may have irritable bowel syndrome (IBS). If so, you may qualify for an investigational research study of a herbal remedy for IBS symptoms. To qualify to participate, you must be a female, between the ages of 18 to 65, and suffer from IBS symptoms. Qualified participants will receive study herbal product medication or placebo, study related testing, and physical exams at no cost. Compensation and parking will be provided for time and travel and insurance is not needed.
Info: (877) 906-7797 or myclinicaltrial.com/ucla

Memory Enhancement Training or Yoga for Older Adults

For those who are suffering from memory loss, concentration difficulties or lack of energy, UCLA is conducting a six-month research study comparing a 60-minute weekly memory enhancement training course to yoga meditation. If you are 55 years of age or older and not currently receiving any psychiatric treatment, you may qualify. Medical and psychiatric evaluations and limited physical exams are provided as a part of the study. Participants will undergo two functional magnetic resonance imaging (fMRI) scans. A complete psychiatric evaluation will be provided. Participants will be compensated.
Info: (310) 794-9523 or (310) 794-4619

Dietary Supplement Research on Memory

This project is designed to study the effects of the dietary supplement curcumin on cognitive impairment. In particular, the study will determine the effects of curcumin on cognitive decline and on the amount of abnormal amyloid protein in the brain. People with memory complaints ages 50 to 90 are encouraged to participate. This study involves eight visits over the course of 18 months. Subjects will be compensated for participation and receive clinically relevant results of assessments.
Info: (310) 825-0545

Long-term effects of adolescent marijuana use study

UCLA researchers are interested in studying the long-term effects of marijuana use in early life. If you are over age 55 now, but used marijuana when you were younger, you may qualify for our research study. We are also recruiting control subjects who never used marijuana. The study involves two five-hour visits; volunteers will be reimbursed for parking costs and paid up to $150 for participation, which includes an MRI, neuropsychiatric testing and blood work.
Info: (310) 794-1021

Menstrual Irregularities and PCOS Study

UCLA researchers are seeking women with and without Polycystic Ovary Syndrome (PCOS). To be eligible, women must be Caucasian and non-Hispanic, between the ages of 18 and 35, have body mass index (BMI) between 18.5 and 25, and have not used hormones (i.e., birth control pills or a Mirena IUD) for the past three months. Participants will receive extensive free medical testing including blood hormone measurements, diabetes screening, ovarian and fat assessment. A small amount of fat will be removed from the abdomen and blood will be drawn for research purposes. Only women with PCOS will take an oral pill that contains either the drug Flutamide or a placebo (sugar pill) for six complete 28-day cycles. The free medical testing will be repeated at the end of the study. Women without PCOS may earn up to $300 and women with PCOS may earn up to $840.
Info: (310) 825-0580; or uclaobgynresearch@mednet.ucla.edu

Family Focused Treatment for Childhood OCD

Does your child have Obsessive Compulsive Disorder (OCD)? Does he/she: Have recurring thoughts that make no sense, but makes him/ her feel bad? Wash excessively or have fear of touching contaminated objects? Check and double-check more than necessary? Have to do things over and over again? This UCLA Research Study for kids and teens ages 8 to 17 with OCD is studying family involvement in non-medication Cognitive-Behavioral Therapy (CBT). Eligible participants will receive 14 weeks free treatment with Cognitive-Behavioral Therapy.
Info: (310) 206-1350

Child Obsessive Compulsive Disorder Study

This UCLA Research Study conducted by Susanna Chang, MD, is investigating the usefulness of a novel computer-based attention training treatment for childhood OCD. We are seeking help from children ages 8 to 17 with OCD as study participants. Participation involves EEG recordings and four weeks of a non-medication attention training treatment.
Info: (310) 825-2064

Obstructive Sleep Apnea (OSA) Research Study

UCLA researchers are seeking patients between the ages of 21 and 75 who have recently been diagnosed with obstructive sleep apnea and have not yet started treatment to participate in a study to see how changes in brain function and structure relate to autonomic impairments. The study is also seeking control participants who are in good health, non-smokers and without sleep disorders. People interested in participating will go through a screening process and those determined eligible will be enrolled in the study. Enrolled participants will be invited to do one or more of the following: MRI scanning; physiological testing; simple, daily home physiological testing, and brief questionnaires using a smart phone. Study participants will not be charged for any study procedure and will be compensated for participation.
Info: (424) 254-8252 or projectdirector@osabrainresearch.org

Pomegranate Juice Study

The UCLA Longevity Center is studying the effect of pomegranate juice on memory. Volunteers between the ages of 50 and 75 are needed. The study lasts one year and includes seven visits to UCLA and $300 compensation for participation.
Info: (310) 825-0545

Developmental Pathways of Internalizing Disorders Study

This UCLA research study, conducted by Cara Kiff, MD, is investigating how stress at home, school and in children's neighborhoods might lead some children to develop anxiety and/or depression. We are also interested in how children's physiology responds to experiences of stress. We are seeking help from children ages 10 to 14 and their mothers. Participation includes a one-time visit to the UCLA campus.
Info: (310) 794-1642 or dpi.study@ucla.edu

Weight Loss After Bariatric Surgery: The Role of Changes in Appetite and Food Preferences

If you are a woman thinking about weight loss surgery, you may be eligible to participate in this research study to explore the role your brain activity - related to appetite, eating habits and food preferences - plays in weight loss after bariatric surgery and if a brain MRI could predict who will be successful in losing weight after surgery.

You must be a woman between 18-50 years of age, right handed, have no neurological or significant psychiatric history, and must be eligible and approved for undergoing weight loss surgery (gastric bypass or sleeve gastrectomy).

Participation involves a screening visit and three MRIs performed one month before, and six months after weight loss surgery. Blood samples, body composition and information about food preferences/eating habits will also be collected. Compensation: Up to $240, receive a free picture of your brain and free parking during the study visits.

This study is conducted by Claudia Sanmiguel, MD, UCLA Program for Ingestive Behavior and Obesity and by Erik Dutson, MD, UCLA Center of Minimally Invasive and Bariatric Surgery.
Info: (310) 206-1758 or (310) 825-3287


For more information about Clinical Trials offered to cancer patients, visit:
www.cancer.ucla.edu/clinical-trials or call UCLA jonsson Comprehensive Cancer Center (JCCC) Clinical Trials Hotline at (888) 798-0719.