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Nasal mucosal biopsy
Definition
A nasal mucosal biopsy is the removal of a small piece of tissue from the lining of the nose so that it can be checked for disease.
Alternative Names
Biopsy - nasal mucosa; Nose biopsy
How the test is performed
A painkiller is sprayed into the nose. In some cases, a numbing shot may be used. A small piece of the tissue that appears abnormal is removed and checked for problems in the laboratory.
How to prepare for the test
No special preparation is necessary. You may be asked to fast for a few hours before the biopsy.
How the test will feel
You may feel pressure or tugging when the tissue is removed. After the numbness wears off, the area may be sore for a few days. A small to moderate amount of bleeding after the procedure is common. If there is bleeding, the blood vessels may be sealed with an electric current or laser.
Why the test is performed
Nasal mucosal biopsy is usually done when abnormal tissue is seen during examination of the nose. It may also be done when problems affecting the mucosal tissue of the nose are suspected.
Normal Values
There are no abnormal growths or tissue.
Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
What abnormal results mean
- Infections such as tuberculosis
- Necrotizing granuloma, a type of tumor
- Nasal polyps
- Nasal tumors
- Sarcoid
- Wegener's disease
What the risks are
- Bleeding from the biopsy site
- Infection
Special considerations
Avoid blowing your nose after the biopsy. Gently squeeze the nostrils shut if there is bleeding. If there is bleeding, the blood vessels may be sealed with an electric current or packing.
Reviewed By: Alan Lipkin, MD, Otolaryngologist, Private Practice, Denver, Colorado. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
