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Robert M. Bilder, PhD, ABPP-CN, PhD


Robert Bilder, PhD

UCLA Physician Robert Bilder, PhD specializes in Neuropsychology.
Preferred Name
Robert M. Bilder, PhD, ABPP-CN
Language Spoken
Hospital Affiliation
Resnick Neuropsychiatric Hospital at UCLA
Ronald Reagan UCLA Medical Center
State License Number
(310) 825-9474
Email Address

UCLA Semel Institute, 740 Westwood Plaza, Los Angeles CA 90024

Neuropsychology - Clinical
PhD, City College, 1984
Research Interest
Neuropsychology, Neuroimaging, Creativity (see http://www.semel.ucla.edu/creativity)
Awards & Recognition
  • National Science Foundation Graduate Fellowship Competition, honorable mention, 1981.
  • Barmack Prize for doctoral thesis, City College of the City University of New York, 1984/1985.
  • Young Investigator Award, International Congress on Schizophrenia Research, 1989.
  • Faculty Research Award, Long Island Jewish Medical Center, 1990-1992.
  • NARSAD - Young Investigator Award, 1992-1994.
  • Winter Workshop on Schizophrenia - Young Scientist Award, 1994.
  • Faculty Research Award, Long Island Jewish Medical Center, 1994-1995.
  • NARSAD - Independent Investigator Award, 1999-2001.
  • Tennenbaum Family Creativity Initiative Award, 2003; Co-Director Tennenbaum Initiative 2006-present.
  • American Psychiatric Institute for Research and Education, Mentor for Resident Research Scholar, 2005.
  • Michael E. Tennenbaum Family Endowed Chair in Creativity Research, 2008-present.
  • David Geffen School of Medicine, Department of Psychiatry & Biobehavioral Sciences Teaching Award, Outstanding Research Mentor, 2009-2010.
  • Fellow, National Academy of Neuropsychology, 2010.
  • Lynn Speedie Lectureship, Kennedy Krieger Institute, 2012.
  • William S. Knowles Lectureship, Monsanto Fellow Symposium, 2012.
  • Jonathan Brodie Lectureship, New York University School of Medicine, 2013.
  • Fellow, American Psychological Assocation, Society of Clinical Neuropsychology, 2013.
  • Max L. Hutt Lectureship, University of Michigan, 2013.
  1. Goldberg E, Antin SP, Bilder RM, Jr., Gerstman LJ, Hughes JE, Mattis S: Retrograde amnesia: possible role of mesencephalic reticular activation in long-term memory. Science 213:1392-1394, 1981.
  2. Goldberg E, Gerstman LJ, Mattis S, Hughes JE, Bilder RM, Jr., Sirio CA: Effects of cholinergic treatment on posttraumatic anterograde amnesia. Arch Neurol 39:581, 1982.
  3. Goldberg E, Gerstman LJ, Mattis S, Hughes JE, Sirio CA, Bilder RM, Jr.: Selective effects of cholinergic treatment on verbal memory in posttraumatic amnesia. J Clin Neuropsychol 4:219-234, 1982.
  4. Mukherjee S, Bilder RM: Commentary on tardive dysmentia. Schizophr Bull 11:189-190, 1985.
  5. Bilder RM, Mukherjee S, Rieder RO, Pandurangi AK: Symptomatic and neuropsychological components of defect states. Schizophr Bull 11:409-419, 1985.
  6. Bilder RM, Goldberg E: Motor perseverations in schizophrenia. Arch Clin Neuropsychol 2:195-214, 1987.
  7. Pandurangi AK, Bilder RM, Rieder RO, Mukherjee S, Hamer RM: Schizophrenic symptoms and deterioration. Relation to computed tomographic findings. J Nerv Ment Dis 176:200-206, 1988.
  8. Bilder RM, Degreef G, Pandurangi AK, Rieder RO, Sackeim HA, Mukherjee S: Neuropsychological deterioration and CT scan findings in chronic schizophrenia. Schizophr Res 1:37-45, 1988.
  9. Degreef G, Mukherjee S, Bilder R, Schnur D: Season of birth and CT scan findings in schizophrenic patients. Biol Psychiatry 24:461-464, 1988.
  10. Goldberg E, Bilder RM, Hughes JE, Antin SP, Mattis S: A reticulo-frontal disconnection syndrome. Cortex 25:687-695, 1989.
  11. Barr WB, Bilder RM, Goldberg E, Kaplan E, Mukherjee S: The neuropsychology of schizophrenic speech. J Commun Disord 22:327-349, 1989.
  12. Bogerts B, Ashtari M, Degreef G, Alvir JM, Bilder RM, Lieberman JA: Reduced temporal limbic structure volumes on magnetic resonance images in first episode schizophrenia. Psychiatry Res 35:1-13, 1990.
  13. Bilder RM, Lipschutz-Broch L, Reiter G, Geisler S, Mayerhoff D, Lieberman JA: Neuropsychological deficits in the early course of first episode schizophrenia. Schizophr Res 5:198-199, 1991.
  14. Bilder RM: Structure-function relations in schizophrenia: brain morphology and neuropsychology. Prog Exp Pers Psychopathol Res 15:183-251, 1992.
  15. Degreef G, Ashtari M, Bogerts B, Bilder RM, Jody DN, Alvir JM, Lieberman JA: Volumes of ventricular system subdivisions measured from magnetic resonance images in first-episode schizophrenic patients. Arch Gen Psychiatry 49:531-537, 1992.
  16. Lieberman JA, Alvir JM, Woerner M, Degreef G, Bilder RM, Ashtari M, Bogerts B, Mayerhoff DI, Geisler SH, Loebel A, et al.: Prospective study of psychobiology in first-episode schizophrenia at Hillside Hospital. Schizophr Bull 18:351-371, 1992.
  17. Bilder RM, Lipschutz-Broch L, Reiter G, Geisler SH, Mayerhoff DI, Lieberman JA: Intellectual deficits in first-episode schizophrenia: evidence for progressive deterioration. Schizophr Bull 18:437-448, 1992.
  18. Bilder RM, Lieberman JA, Kim Y, Alvir J, Reiter G. Methylphenidate and neuroleptic effects on oral word production in schizophrenia. Neuropsychiatry, Neuropsychology and Behavioral Neurology, 5, 262-271, 1992.
  19. Bilder RM, Turkel E, Lipschutz-Broch L, Lieberman JA: Antipsychotic medication effects on neuropsychological functions. Psychopharmacol Bull 28:353-366, 1992.
  20. Bogerts B, Lieberman JA, Ashtari M, Bilder RM, Degreef G, Lerner G, Johns C, Masiar S: Hippocampus-amygdala volumes and psychopathology in chronic schizophrenia. Biol Psychiatry 33:236-246, 1993.
  21. Chakos MH, Lieberman JA, Bilder RM, Borenstein M, Lerner G, Bogerts B, Wu H, Kinon B, Ashtari M: Increase in caudate nuclei volumes of first-episode schizophrenic patients taking antipsychotic drugs. Am J Psychiatry 151:1430-1436, 1994.
  22. Bilder RM, Wu H, Bogerts B, Degreef G, Ashtari M, Alvir JM, Snyder PJ, Lieberman JA: Absence of regional hemispheric volume asymmetries in first-episode schizophrenia. Am J Psychiatry 151:1437-1447, 1994.
  23. Bilder RM, Wu H, Chakos MH, Bogerts B, Pollack S, Aronowitz J, Ashtari M, Degreef G, Kane JM, Lieberman JA: Cerebral morphometry and clozapine treatment in schizophrenia. J Clin Psychiatry 55 Suppl B:53-56, 1994.
  24. Bilder RM, Bogerts B, Ashtari M, Wu H, Alvir JM, Jody D, Reiter G, Bell L, Lieberman JA: Anterior hippocampal volume reductions predict frontal lobe dysfunction in first episode schizophrenia. Schizophr Res 17:47-58, 1995.
  25. Chakos MH, Lieberman JA, Alvir J, Bilder R, Ashtari M: Caudate nuclei volumes in schizophrenic patients treated with typical antipsychotics or clozapine. Lancet 345:456-457, 1995.
  26. Snyder PJ, Bilder RM, Wu H, Bogerts B, Lieberman JA: Cerebellar volume asymmetries are related to handedness: a quantitative MRI study. Neuropsychologia 33:407-419, 1995.
  27. Lieberman JA, Koreen AR, Chakos M, Sheitman B, Woerner M, Alvir JM, Bilder R: Factors influencing treatment response and outcome of first-episode schizophrenia: implications for understanding the pathophysiology of schizophrenia. J Clin Psychiatry 57 Suppl 9:5-9, 1996.
  28. Barr WB, Ashtari M, Bilder RM, Degreef G, Lieberman JA: Brain morphometric comparison of first-episode schizophrenia and temporal lobe epilepsy. Br J Psychiatry 170:515-519, 1997.
  29. Bilder RM: Neurocognitive impairment in schizophrenia and how it affects treatment options. Can J Psychiatry 42:255-264, 1997.
  30. Chakos MH, Shirakawa O, Lieberman J, Lee H, Bilder R, Tamminga CA: Striatal enlargement in rats chronically treated with neuroleptic. Biol Psychiatry 44:675-684, 1998.
  31. Grube BS, Bilder RM, Goldman RS: Meta-analysis of symptom factors in schizophrenia. Schizophr Res 31:113-120, 1998.
  32. Snyder PJ, Bogerts B, Wu H, Bilder RM, Deoras KS, Lieberman JA: Absence of the adhesio interthalamica as a marker of early developmental neuropathology in schizophrenia: an MRI and postmortem histologic study. J Neuroimaging 8:159-163, 1998.
  33. Bilder RM, Wu H, Bogerts B, Ashtari M, Robinson D, Woerner M, Lieberman JA, Degreef G: Cerebral volume asymmetries in schizophrenia and mood disorders: a quantitative magnetic resonance imaging study. Int J Psychophysiol 34:197-205, 1999.
  34. Leadbetter RA, Shutty MS, Jr., Elkashef AM, Kirch DG, Spraggins T, Cail WS, Wu H, Bilder RM, Lieberman JA, Wyatt RJ: MRI changes during water loading in patients with polydipsia and intermittent hyponatremia. Am J Psychiatry 156:958-960, 1999.
  35. Lee H, Tarazi FI, Chakos M, Wu H, Redmond M, Alvir JM, Kinon BJ, Bilder R, Creese I, Lieberman JA: Effects of chronic treatment with typical and atypical antipsychotic drugs on the rat striatum. Life Sci 64:1595-1602, 1999.
  36. Robinson D, Woerner MG, Alvir JM, Bilder R, Goldman R, Geisler S, Koreen A, Sheitman B, Chakos M, Mayerhoff D, Lieberman JA: Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder. Arch Gen Psychiatry 56:241-247, 1999.
  37. Robinson DG, Woerner MG, Alvir JM, Geisler S, Koreen A, Sheitman B, Chakos M, Mayerhoff D, Bilder R, Goldman R, Lieberman JA: Predictors of treatment response from a first episode of schizophrenia or schizoaffective disorder. Am J Psychiatry 156:544-549, 1999.
  38. Szeszko PR, Bilder RM, Dunlop JA, Walder DJ, Lieberman JA: Longitudinal assessment of methylphenidate effects on oral word production and symptoms in first-episode schizophrenia at acute and stabilized phases. Biol Psychiatry 45:680-686, 1999.
  39. Szeszko PR, Bilder RM, Lencz T, Pollack S, Alvir JM, Ashtari M, Wu H, Lieberman JA: Investigation of frontal lobe subregions in first-episode schizophrenia. Psychiatry Res 90:1-15, 1999.
  40. Szeszko PR, Robinson D, Alvir JM, Bilder RM, Lencz T, Ashtari M, Wu H, Bogerts B: Orbital frontal and amygdala volume reductions in obsessive-compulsive disorder. Arch Gen Psychiatry 56:913-919, 1999.
  41. Bilder RM, Goldman RS, Robinson D, Reiter G, Bell L, Bates JA, Pappadopulos E, Willson DF, Alvir JM, Woerner MG, Geisler S, Kane JM, Lieberman JA: Neuropsychology of first-episode schizophrenia: initial characterization and clinical correlates. Am J Psychiatry 157:549-559, 2000.
  42. Christensen BK, Bilder RM: Dual cytoarchitectonic trends: an evolutionary model of frontal lobe functioning and its application to psychopathology. Can J Psychiatry 45:247-256, 2000.
  43. Szeszko PR, Bilder RM, Lencz T, Ashtari M, Goldman RS, Reiter G, Wu H, Lieberman JA: Reduced anterior cingulate gyrus volume correlates with executive dysfunction in men with first-episode schizophrenia. Schizophr Res 43:97-108, 2000.
  44. Lencz T, Bilder RM, Cornblatt B: The timing of neurodevelopmental abnormality in schizophrenia: an integrative review of the neuroimaging literature. CNS Spectr 6:233-255, 2001.
  45. Lencz T, Cornblatt B, Bilder RM: Neurodevelopmental models of schizophrenia: pathophysiologic synthesis and directions for intervention research. Psychopharmacol Bull 35:95-125, 2001.
  46. Lieberman J, Chakos M, Wu H, Alvir J, Hoffman E, Robinson D, Bilder R: Longitudinal study of brain morphology in first episode schizophrenia. Biol Psychiatry 49:487-499, 2001.
  47. Pine DS, Fyer A, Grun J, Phelps EA, Szeszko PR, Koda V, Li W, Ardekani B, Maguire EA, Burgess N, Bilder RM: Methods for developmental studies of fear conditioning circuitry. Biol Psychiatry 50:225-228, 2001.
  48. Pine DS, Grun J, Zarahn E, Fyer A, Koda V, Li W, Szeszko PR, Ardekani B, Bilder RM: Cortical brain regions engaged by masked emotional faces in adolescents and adults: an fMRI study. Emotion 1:137-147, 2001.
  49. Sevy S, Robinson DG, Holloway S, Alvir JM, Woerner MG, Bilder R, Goldman R, Lieberman J, Kane J: Correlates of substance misuse in patients with first-episode schizophrenia and schizoaffective disorder. Acta Psychiatr Scand 104:367-374, 2001.
  50. Zuffante P, Leonard CM, Kuldau JM, Bauer RM, Doty EG, Bilder RM: Working memory deficits in schizophrenia are not necessarily specific or associated with MRI-based estimates of area 46 volumes. Psychiatry Res 108:187-209, 2001.
  51. Ardekani BA, Choi SJ, Hossein-Zadeh GA, Porjesz B, Tanabe JL, Lim KO, Bilder R, Helpern JA, Begleiter H: Functional magnetic resonance imaging of brain activity in the visual oddball task. Brain Res Cogn Brain Res 14:347-356, 2002.
  52. Bilder RM, Goldman RS, Volavka J, Czobor P, Hoptman M, Sheitman B, Lindenmayer JP, Citrome L, McEvoy J, Kunz M, Chakos M, Cooper TB, Horowitz TL, Lieberman JA: Neurocognitive effects of clozapine, olanzapine, risperidone, and haloperidol in patients with chronic schizophrenia or schizoaffective disorder. Am J Psychiatry 159:1018-1028, 2002.
  53. Bilder RM, Volavka J, Czobor P, Malhotra AK, Kennedy JL, Ni X, Goldman RS, Hoptman MJ, Sheitman B, Lindenmayer JP, Citrome L, McEvoy JP, Kunz M, Chakos M, Cooper TB, Lieberman JA: Neurocognitive correlates of the COMT Val(158)Met polymorphism in chronic schizophrenia. Biol Psychiatry 52:701-707, 2002.
  54. Citrome L, Bilder RM, Volavka J: Managing treatment-resistant schizophrenia: evidence from randomized clinical trials. J Psychiatr Pract 8:205-215, 2002.
  55. Goldstein RZ, Giovannetti T, Schullery M, Zuffante PA, Lieberman JA, Robinson DG, Barr WB, Bilder RM: Neurocognitive correlates of response to treatment in formal thought disorder in patients with first-episode schizophrenia. Neuropsychiatry Neuropsychol Behav Neurol 15:88-98, 2002.
  56. Gunduz H, Wu H, Ashtari M, Bogerts B, Crandall D, Robinson DG, Alvir J, Lieberman J, Kane J, Bilder R: Basal ganglia volumes in first-episode schizophrenia and healthy comparison subjects. Biol Psychiatry 51:801-808, 2002.
  57. Hoptman MJ, Volavka J, Johnson G, Weiss E, Bilder RM, Lim KO: Frontal white matter microstructure, aggression, and impulsivity in men with schizophrenia: a preliminary study. Biol Psychiatry 52:9-14, 2002.
  58. Malhotra AK, Bates JA, Jaeger J, Petrides G, Robinson DG, Bilder RM, Nassauer KW: No evidence for phenotypic variation between probands in case-control versus family-based association studies of schizophrenia. Am J Med Genet 114:509-511, 2002.
  59. Pine DS, Grun J, Maguire EA, Burgess N, Zarahn E, Koda V, Fyer A, Szeszko PR, Bilder RM: Neurodevelopmental aspects of spatial navigation: a virtual reality fMRI study. Neuroimage 15:396-406, 2002.
  60. Robinson DG, Woerner MG, Alvir JM, Bilder RM, Hinrichsen GA, Lieberman JA: Predictors of medication discontinuation by patients with first-episode schizophrenia and schizoaffective disorder. Schizophr Res 57:209-219, 2002.
  61. Szeszko PR, Strous RD, Goldman RS, Ashtari M, Knuth KH, Lieberman JA, Bilder RM: Neuropsychological correlates of hippocampal volumes in patients experiencing a first episode of schizophrenia. Am J Psychiatry 159:217-226, 2002.
  62. Weiss EM, Bilder RM, Fleischhacker WW: The effects of second-generation antipsychotics on cognitive functioning and psychosocial outcome in schizophrenia. Psychopharmacology (Berl) 162:11-17, 2002.
  63. Fan J, Gay Snodgrass J, Bilder RM: Functional magnetic resonance imaging of source versus item memory. Neuroreport 14:2275-2281, 2003.
  64. Giovannetti T, Goldstein RZ, Schullery M, Barr WB, Bilder RM: Category fluency in first-episode schizophrenia. J Int Neuropsychol Soc 9:384-393, 2003.
  65. Keefe RS, Mohs RC, Bilder RM, Harvey PD, Green MF, Meltzer HY, Gold JM, Sano M: Neurocognitive assessment in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project schizophrenia trial: development, methodology, and rationale. Schizophr Bull 29:45-55, 2003.
  66. Lencz T, Bilder RM, Turkel E, Goldman RS, Robinson D, Kane JM, Lieberman JA: Impairments in perceptual competency and maintenance on a visual delayed match-to-sample test in first-episode schizophrenia. Arch Gen Psychiatry 60:238-243, 2003.
  67. Monk CS, McClure EB, Nelson EE, Zarahn E, Bilder RM, Leibenluft E, Charney DS, Ernst M, Pine DS: Adolescent immaturity in attention-related brain engagement to emotional facial expressions. Neuroimage 20:420-428, 2003.
  68. Szeszko PR, Goldberg E, Gunduz-Bruce H, Ashtari M, Robinson D, Malhotra AK, Lencz T, Bates J, Crandall DT, Kane JM, Bilder RM: Smaller anterior hippocampal formation volume in antipsychotic-naive patients with first-episode schizophrenia. Am J Psychiatry 160:2190-2197, 2003.
  69. Szeszko PR, Gunning-Dixon F, Ashtari M, Snyder PJ, Lieberman JA, Bilder RM: Reversed cerebellar asymmetry in men with first-episode schizophrenia. Biol Psychiatry 53:450-459, 2003.
  70. Szeszko PR, Gunning-Dixon F, Goldman RS, Bates J, Ashtari M, Snyder PJ, Lieberman JA, Bilder RM: Lack of normal association between cerebellar volume and neuropsychological functions in first-episode schizophrenia. Am J Psychiatry 160:1884-1887, 2003.
  71. Szeszko PR, Vogel J, Ashtari M, Malhotra AK, Bates J, Kane JM, Bilder RM, Frevert T, Lim K: Sex differences in frontal lobe white matter microstructure: a DTI study. Neuroreport 14:2469-2473, 2003.
  72. Ashtari M, Lencz T, Zuffante P, Bilder R, Clarke T, Diamond A, Kane J, Szeszko P: Left middle temporal gyrus activation during a phonemic discrimination task. Neuroreport 15:389-393, 2004.
  73. Bilder RM, Volavka J, Lachman HM, Grace AA: The catechol-O-methyltransferase polymorphism: relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes. Neuropsychopharmacology 29:1943-1961, 2004.
  74. McClure EB, Monk CS, Nelson EE, Zarahn E, Leibenluft E, Bilder RM, Charney DS, Ernst M, Pine DS: A developmental examination of gender differences in brain engagement during evaluation of threat. Biol Psychiatry 55:1047-1055, 2004.
  75. Narr KL, Bilder RM, Kim S, Thompson PM, Szeszko P, Robinson D, Luders E, Toga AW: Abnormal gyral complexity in first-episode schizophrenia. Biol Psychiatry 55:859-867, 2004.
  76. Narr KL, Thompson PM, Szeszko P, Robinson D, Jang S, Woods RP, Kim S, Hayashi KM, Asunction D, Toga AW, Bilder RM: Regional specificity of hippocampal volume reductions in first-episode schizophrenia. Neuroimage 21:1563-1575, 2004.
  77. Nolan KA, Bilder RM, Lachman HM, Volavka J: Catechol O-methyltransferase Val158Met polymorphism in schizophrenia: differential effects of Val and Met alleles on cognitive stability and flexibility. Am J Psychiatry 161:359-361, 2004.
  78. Robinson DG, Woerner MG, McMeniman M, Mendelowitz A, Bilder RM: Symptomatic and functional recovery from a first episode of schizophrenia or schizoaffective disorder. Am J Psychiatry 161:473-479, 2004.
  79. Szeszko PR, Bates J, Robinson D, Kane J, Bilder RM: Investigation of unirhinal olfactory identification in antipsychotic-free patients experiencing a first-episode schizophrenia. Schizophr Res 67:219-225, 2004.
  80. Volavka J, Bilder R, Nolan K: Catecholamines and Aggression: The Role of COMT and MAO Polymorphisms. Ann N Y Acad Sci 1036:393-398, 2004.
  81. Hoptman MJ, Volavka J, Weiss EM, Czobor P, Szeszko PR, Gerig G, Chakos M, Blocher J, Citrome LL, Lindenmayer JP, Sheitman B, Lieberman JA, Bilder RM: Quantitative MRI measures of orbitofrontal cortex in patients with chronic schizophrenia or schizoaffective disorder. Psychiatry Res 140:133-145, 2005.
  82. Narr KL, Bilder RM, Toga AW, Woods RP, Rex DE, Szeszko PR, Robinson D, Sevy S, Gunduz-Bruce H, Wang YP, DeLuca H, Thompson PM: Mapping cortical thickness and gray matter concentration in first episode schizophrenia. Cereb Cortex 15:708-719, 2005.
  83. Narr KL, Toga AW, Szeszko P, Thompson PM, Woods RP, Robinson D, Sevy S, Wang Y, Schrock K, Bilder RM: Cortical thinning in cingulate and occipital cortices in first episode schizophrenia. Biol Psychiatry 58:32-40, 2005.
  84. Rhinewine JP, Lencz T, Thaden EP, Cervellione KL, Burdick KE, Henderson I, Bhaskar S, Keehlisen L, Kane J, Kohn N, Fisch GS, Bilder RM, Kumra S: Neurocognitive profile in adolescents with early-onset schizophrenia: clinical correlates. Biol Psychiatry 58:705-712, 2005.
  85. Rupp CI, Fleischhacker WW, Kemmler G, Kremser C, Bilder RM, Mechtcheriakov S, Szeszko PR, Walch T, Scholtz AW, Klimbacher M, Maier C, Albrecht G, Lechner-Schoner T, Felber S, Hinterhuber H: Olfactory functions and volumetric measures of orbitofrontal and limbic regions in schizophrenia. Schizophr Res 74:149-161, 2005.
  86. Szeszko PR, Ardekani BA, Ashtari M, Kumra S, Robinson DG, Sevy S, Gunduz-Bruce H, Malhotra AK, Kane JM, Bilder RM, Lim KO: White matter abnormalities in first-episode schizophrenia or schizoaffective disorder: a diffusion tensor imaging study. Am J Psychiatry 162:602-605, 2005.
  87. Szeszko PR, Ardekani BA, Ashtari M, Malhotra AK, Robinson DG, Bilder RM, Lim KO: White matter abnormalities in obsessive-compulsive disorder: a diffusion tensor imaging study. Arch Gen Psychiatry 62:782-790, 2005.
  88. Szeszko PR, Lipsky R, Mentschel C, Robinson D, Gunduz-Bruce H, Sevy S, Ashtari M, Napolitano B, Bilder RM, Kane JM, Goldman D, Malhotra AK: Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation. Mol Psychiatry 10:631-636, 2005.
  89. Bilder RM, Reiter G, Bates J, Lencz T, Szeszko P, Goldman RS, Robinson D, Lieberman JA, Kane JM: Cognitive development in schizophrenia: follow-back from the first episode. J Clin Exp Neuropsychol 28:270-282, 2006.
  90. Hoptman MJ, Volavka J, Czobor P, Gerig G, Chakos M, Blocher J, Citrome LL, Sheitman B, Lindenmayer JP, Lieberman JA, Bilder RM: Aggression and quantitative MRI measures of caudate in patients with chronic schizophrenia or schizoaffective disorder. J Neuropsychiatry Clin Neurosci 18:509-515, 2006.
  91. Keefe RS, Bilder RM, Harvey PD, Davis SM, Palmer BW, Gold JM, Meltzer HY, Green MF, Miller del D, Canive JM, Adler LW, Manschreck TC, Swartz M, Rosenheck R, Perkins DO, Walker TM, Stroup TS, McEvoy JP, Lieberman JA: Baseline neurocognitive deficits in the CATIE schizophrenia trial. Neuropsychopharmacology 31:2033-2046, 2006.
  92. Narr KL, Bilder RM, Woods RP, Thompson PM, Szeszko P, Robinson D, Ballmaier M, Messenger B, Wang Y, Toga AW: Regional specificity of cerebrospinal fluid abnormalities in first episode schizophrenia. Psychiatry Res 146:21-33, 2006.
  93. Narr KL, Woods RP, Thompson PM, Szeszko P, Robinson D, Dimtcheva T, Gurbani M, Toga AW, Bilder RM: Relationships between IQ and regional cortical gray matter thickness in healthy adults. Cereb Cortex 17:2163-71, 2007.
  94. Szeszko PR, Betensky JD, Mentschel C, Gunduz-Bruce H, Lencz T, Ashtari M, Malhotra AK, Bilder RM: Increased stress and smaller anterior hippocampal volume. Neuroreport 17:1825-1828, 2006.
  95. Gunduz-Bruce H, Narr KL, Gueorguieva R, Toga AW, Szeszko PR, Ashtari M, Robinson DG, Sevy S, Kane JM, Bilder RM: CSF sub-compartments in relation to plasma osmolality in healthy controls and in patients with first episode schizophrenia. Psychiatry Res 155:57-66, 2007.
  96. Gunduz-Bruce H, Szeszko PR, Gueorguieva R, Ashtari M, Robinson DG, Kane JM, Bilder RM: Cortisol levels in relation to hippocampal sub-regions in subjects with first episode schizophrenia. Schizophr Res 94:281-287, 2007.
  97. Keefe RS, Bilder RM, Davis SM, Harvey PD, Palmer BW, Gold JM, Meltzer HY, Green MF, Capuano G, Stroup TS, McEvoy JP, Swartz MS, Rosenheck RA, Perkins DO, Davis CE, Hsiao JK, Lieberman JA: Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial. Arch Gen Psychiatry 64:633-647, 2007.
  98. Narr KL, Bilder RM, Luders E, Thompson PM, Woods RP, Robinson D, Szeszko PR, Dimtcheva T, Gurbani M, Toga AW: Asymmetries of cortical shape: Effects of handedness, sex and schizophrenia. Neuroimage 34:939-948, 2007.
  99. Pandina GJ, Bilder R, Harvey PD, Keefe RS, Aman MG, Gharabawi G: Risperidone and cognitive function in children with disruptive behavior disorders. Biol Psychiatry 62:226-234, 2007.
  100. Sabb FW, Bilder RM, Chou M, Bookheimer SY: Working memory effects on semantic processing: Priming differences in pars orbitalis. Neuroimage, 2007.[Epub ahead of print]
  101. Szeszko PR, Robinson DG, Sevy S, Kumra S, Rupp CI, Betensky JD, Lencz T, Ashtari M, Kane JM, Malhotra AK, Gunduz-Bruce H, Napolitano B, Bilder RM: Anterior cingulate grey-matter deficits and cannabis use in first-episode schizophrenia. Br J Psychiatry 190:230-236, 2007.
  102. Luders E, Nar KL, Bilder RM, Thompson PM, Szeszko PR, Hamilton L, Toga AW. Positive correlations between corpus callosum thickness and intelligence. Neuroimage. 2007 Jul 12; [Epub ahead of print]
  103. Hamilton LS, Narr KL, Luders E, Szeszko PR, Thompson PM, Bilder RM, Toga AW. Asymmetries of cortical thickness: effects of handedness, sex, and schizophrenia. Neuroreport. 2007 Sep 17;18(14):1427-1431.
  104. Harvey PD, Sacchetti E, Galluzzo A, Romeo F, Gorini B, Bilder RM, Loebel AD. A randomized double-blind comparison of ziprasidone vs. clozapine for cognition in patients with schizophrenia selected for resistance or intolerance to previous treatment. Schizophr Res. 2007 Dec 10; [Epub ahead of print]
  105. Shattuck DW, Mirza M, Adisetiyo V, Hojatkashani C, Salamon G, Narr KL, Poldrack RA, Bilder RM, Toga AW. Construction of a 3D probabilistic atlas of human cortical structures. Neuroimage, 2008 Feb 1;39(3):1064-80. Epub 2007 Nov 26. PMID: 18037310
  106. Luders E, Narr KI, Bilder RM, Szeszko PR, Gurbani MN, Hamilton L, Toga AW, Gaser C: Mapping the relationship between cortical convolution and intelligence: Effects of gender. Cerebral Cortex 18:2019-2026, 2008.
  107. Szeszko PR, Robinson DG, Ashtari M, Vogel J, Betensky J, Sevy S, Ardekani BA, Lencz T, Malhotra AK, McCormack J, Miller R, Lim KO, Gunduz-Bruce H, Kane JM, Bilder RM. Clinical and neuropsychological correlates of white matter abnormalities in recent onset schizophrenia. Neuropsychopharmacology. 2008 Apr;33(5):976-84. PMID: 17581532
  108. Sabb FW, Bearden CE, Glahn DC, Parker DS, Freimer N, Bilder RM. A collaborative knowledge base for cognitive phenomics. Mol Psychiatry. 2008 Apr;13(4):350-60. Epub 2008 Jan 8. PMID: 18180765
  109. Foerde K, Poldrack RA, Khan BJ, Sabb FW, Bookheimer SY, Bilder RM, Guthrie D, Granholm E, Nuechterlein KH, Marder SR, Asarnow RF. Selective corticostriatal dysfunction in schizophrenia: examination of motor and cognitive skill learning. Neuropsychology. 2008 Jan;22(1):100-9. Erratum in: Neuropsychology. 2008 May;22(3):418. PMID: 18211159
  110. Bilder RM. Phenomics: building scaffolds for biological hypotheses in the post-genomic era. Biol Psychiatry. 2008 Mar 1;63(5):439-40. PMID: 18267152
  111. Szeszko PR, Hodgkinson CA, Robinson DG, DeRosse P, Bilder RM, Lencz T, Burdick KE, Napolitano B, Betensky JD, Kane JA, Goldman D, Malhotra AK: DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia. Biological Psychology 79:103-110, 2008.
  112. Harvey PD, Sacchetti E, Galluzzo A, Romeo F, Gorini B, Bilder RM, Loebel AD: A randomized double-blind comparison of ziprasidone vs. clozapine for cognition in patients with schizophrenia selected for resistance or intolerance to previous treatment. Schizophr Res 105:138-143, 2008.
  113. Betensky JD, Robinson DG, Gunduz-Bruce H, Sevy S, Lencz T, Kane JM, Malhotra AK, Miller R, McCormack J, Bilder RM, Szeszko PR. Patterns of stress in schizophrenia. Psychiatry Res. 2008 May 29. [Epub ahead of print] PMID: 18514323
  114. Ventura J, Cienfuegos A, Boxer O, <strong>Bilder R</strong>. Clinical global impression of cognition in schizophrenia (CGI-CogS): reliability and validity of a co-primary measure of cognition. Schizophr Res. 2008 Nov;106(1):59-69. PMID: 17900866
  115. Coscia DM, Narr KL, Robinson DG, Hamilton LS, Sevy S, Burdick KE, Gunduz-Bruce H, McCormack J, Bilder RM, Szeszko PR. Volumetric and shape analysis of the thalamus in first-episode schizophrenia. Hum Brain Mapp. 2009 Apr;30(4):1236-45.PMID: 18570200 [PubMed - indexed for MEDLINE]
  116. Bilder RM, Sabb FW, Cannon TD, London ED, Jentsch JD, Parker DS, Poldrack RA, Evans C, Freimer NB, Phenomics: The systematic study of phenotypes on a genome-wide scale. Neuroscience. 2009 Jan 20. [Epub ahead of print] PMID: 19344640
  117. Sabb FW, Burggren AC, Higier RG, Fox J, He J, Parker DS, Poldrack RA, Chu W, Cannon TD, Freimer NB, Bilder RM. Challenges in Phenotype Definition in the Whole-Genome era: Multivariate Models of Memory and Intelligence. Neuroscience. 2009 May 15. [Epub ahead of print]PMID: 19450667
  118. Narr KL, Szeszko PR, Lencz T, Woods RP, Hamilton LS, Phillips O, Robinson D, Burdick KE, DeRosse P, Kucherlapati R, Thompson PM, Toga AW, Malhotra AK, Bilder RM: DTNBP1 Is Associated with Imaging Phenotypes in Schizophrenia. Human Brain Mapping 30:3783-3794, 2009. PMID: 19449336
  119. Bilder RM, Sabb FW, Parker DS, Kalar D, Chu WW, Fox J, Freimer NB, Poldrack RA. Cognitive ontologies for neuropsychiatric phenomics research. Cogn Neuropsychiatry. 2009 Jul;14(4):419-50.
  120. Lee B, London ED, Poldrack RA, Farahi J, Nacca A, Monterosso JR, Mumford JA, Bokarius AV, Dahlbom M, Mukherjee J, Bilder RM, Brody AL, Mandelkern MA. Striatal Dopamine D2/D3 Receptor Availability Is Reduced in Methamphetamine Dependence and Is Linked to Impulsivity.J Neurosci. 2009 Nov 25;29(47):14734-14740. PMID: 19940168
  121. Ghahremani DG, Monterosso J, Jentsch JD, Bilder RM, Poldrack RA. Neural Components Underlying Behavioral Flexibility in Human Reversal Learning. Cereb Cortex. 20:1843-1852, 2010. PMID: 19915091
  122. Pandina GJ, Ness S, Polverejan E, Yuen E, Eerdekens M, Bilder RM, Ford L. Cognitive Effects of Topiramate in Migraine Patients Aged 12 Through 17 Years.Pediatr Neurol. 2010 Mar;42(3):187-195. PMID: 20159428
  123. Ardekani BA, Tabesh A, Sevy S, Robinson DG, Bilder RM, Szeszko PR. Diffusion tensor imaging reliably differentiates patients with schizophrenia from healthy volunteers. Hum Brain Mapp. 2011 Jan;32(1):1-9. PMID: 20205252
  124. Cohen JR, Asarnow RF, Sabb FW, Bilder RM, Bookheimer SY, Knowlton BJ, Poldrack RA. A unique adolescent response to reward prediction errors. Nat Neurosci. 2010 May 16. [Epub ahead of print]PMID: 20473290
  125. Ventura J, Reise SP, Keefe RS, Baade LE, Gold JM, Green MF, Kern RS, Mesholam-Gately R, Nuechterlein KH, Seidman LJ, Bilder RM. The Cognitive Assessment Interview (CAI): development and validation of an empirically derived, brief interview-based measure of cognition. Schizophr Res. 2010 Aug;121(1-3):24-31. PMID: 20542412
  126. Cohen JR, Asarnow RF, Sabb FW, Bilder RM, Bookheimer SY, Knowlton BJ, Poldrack RA. Decoding developmental differences and individual variability in response inhibition through predictive analyses across individuals. Front Hum Neurosci. 2010 Jul 2;4:47. PMID: 20661296
  127. Lencz T, Szeszko PR, Derosse P, Burdick KE, Bromet EJ, Bilder RM, Malhotra AK. A Schizophrenia Risk Gene, ZNF804A, Influences Neuroanatomical and Neurocognitive Phenotypes.Neuropsychopharmacology. 2010 Oct;35(11):2284-91. PMID: 20664580
  128. Bilder RM. Neuropsychology 3.0: Evidence-based science and practice. J Int Neuropsychol Soc. 2011, 17: 7-13 PMID: 21092355. DOI: 10.1017/S1355617711000270
  129. Reise SP, Ventura J, Keefe RS, Baade LE, Gold JM, Green MF, Kern RS, Mesholam-Gately R, Nuechterlein KH, Seidman LJ, Bilder R. Bifactor and item response theory analyses of interviewer report scales of cognitive impairment in schizophrenia. Psychol Assess. 2011 Mar;23(1):245-61. PMID: 21381848 [PubMed - in process]
  130. Hurford IM, Marder SR, Keefe RS, Reise SP, Bilder RM. A Brief Cognitive Assessment Tool for Schizophrenia: Construction of a Tool for Clinicians. Schizophr Bull. PMID: 19776205 Schizophr Bull. 2011 May;37(3):538-45. PMID: 19776205
  131. Bilder RM, Howe A, Novak N, Sabb FW, Parker DS. The genetics of cognitive impairment in schizophrenia: a phenomic perspective. Trends Cogn Sci. 2011 Sep;15(9):428-35. PMID: 21816658
  132. Poldrack RA, Kittur A, Kalar D, Miller E, Seppa C, Gil Y, Parker DS, Sabb FW, Bilder RM. The Cognitive Atlas: Towards a knowledge foundation for cognitive neuroscience. Frontiers in Neuroinformatics, 2011, 5, 17; Epub Sep 6. PMID: 21922006 doi: 10.3389/fninf.2011.00017
  133. Szeszko PR, Narr KL, Phillips OR, McCormack J, Sevy S, Gunduz-Bruce H, Kane JM, Bilder RM, Robinson DG. Magnetic Resonance Imaging Predictors of Treatment Response in First-Episode Schizophrenia. Schizophr Bull. 2012 May;38(3):569-78. Epub 2010 Nov 17. PMID: 21084552
  134. Levine AJ, Sinsheimer JS, Bilder R, Shapshak P, Singer EJ. Functional polymorphisms in dopamine-related genes: Effect on neurocognitive functioning in HIV+ adults. J Clin Exp Neuropsychol. 2012 Jan;34(1):78-91. Epub 2011 Nov 14. PMID: 22082040
  135. Ventura J, Reise SP, Keefe RS, Hurford IM, Wood RC, Bilder RM. The Cognitive Assessment Interview (CAI): Reliability and Validity of a Brief Interview-Based Measure of Cognition. Schizophr Bull. 2012 Feb 10. [Epub ahead of print] PMID: 22328641
  136. Wellington RL, Bilder RM, Napolitano B, Szeszko PR. 1. Effects of age on prefrontal subregions and hippocampal volumes in young and middle-aged healthy humans. Hum Brain Mapp. 2013; 34(9): 2129-2140. doi: 10.1002/hbm.22054. [Epub ahead of print] PMID: 22488952 [PubMed - as supplied by publisher]
  137. Bilder RM. Executive control: balancing stability and flexibility via the duality of evolutionary neuroanatomical trends. Dialogues Clin Neurosci. 2012 Mar;14(1):39-47. PMID: 22577303
  138. Clark L, Boxer O, Sahakian BJ, Bilder RM. Research methods: cognitive neuropsychological methods. Handb Clin Neurol. 2012;106:75-87. PMID: 22608616; doi: 10.1016/B978-0-444-52002-9.00005-X.
  139. Wagshal D, Knowlton BJ, Cohen JR, Poldrack RA, Bookheimer SY, Bilder RM, Fernandez VG, Asarnow RF. Deficits in probabilistic classification learning and liability for schizophrenia. Psychiatry Res. 2012 Dec 30; 200(2-3):167-72. doi: 10.1016/j.psychres.2012.06.009. Epub 2012 Jul 2.
  140. Gruner P, Christian C, Robinson DG, Sevy S, Gunduz-Bruce H, Napolitano B, Bilder RM, Szeszko PR. Pituitary volume in first-episode schizophrenia. Psychiatry Res. 2012, 203(1):100-2. doi: 10.1016/j.pscychresns.2011.09.017. PMID: 22858406
  141. Chengappa KN, Turkin SR, Desanti S, Bowie CR, Brar JS, Schlicht PJ, Murphy SL, Hetrick ML, Bilder R, Fleet D. A preliminary, randomized, double-blind, placebo-controlled trial of l-carnosine to improve cognition in schizophrenia. Schizophr Res. 2012 Oct 22. pii: S0920-9964(12)00571-3. doi: 10.1016/j.schres.2012.10.001. [Epub ahead of print] PMID: 23099060
  142. Pandina G, Bilder R, Turkoz I, Alphs L. Schizophr Res. Identification of clinically meaningful relationships among cognition, functionality, and symptoms in subjects with schizophrenia or schizoaffective disorder. Schizophr Res. 2013 Feb;143(2-3):312-8. doi: 10.1016/j.schres.2012.11.031. Epub 2012 Dec 28. PMID: 23276482
  143. Thames AD, Hinkin CH, Byrd DA, Bilder RM, Duff KJ, Mindt MR, Arentoft A, Streiff V. Effects of Stereotype Threat, Perceived Discrimination, and Examiner Race on Neuropsychological Performance: Simple as Black and White? J Int Neuropsychol Soc. 2013 Feb 7:1-11. [Epub ahead of print] PMID: 23388089
  144. Thakkar KN, Congdon E, Poldrack RA, Sabb Fw, London ED, Cannon TD, Bilder RM. Women are more sensitive than men to prior trial events on the Stop-signal task. British Journal of Psychology, 2014, 105: 254–272, DOI: 10.1111/bjop.12034. PMID: 24754812
  145. Bilder RM, Howe AS, Sabb FW. Multilevel Models from Biology to Psychology: Mission Impossible? Journal of Abnormal Psychology, 2013 May 6. [Epub ahead of print] PMID: 23647123.
  146. Montojo CA, Jalbrzikowski M, Congdon E, Domicoli S, Chow C1, Dawson C, Karlsgodt KH, Bilder RM, Bearden CE. Neural substrates of response inhibition deficits in 22q11.2 deletion syndrome. Cereb Cortex. 2013 Oct 31. [Epub ahead of print] PMID: 24177988
  147. Helfinstein SM, Schonberg T, Congdon E, Karlsgodt KH, Mumford JA, Sabb FW, Cannon TD, London ED, Bilder RM, Poldrack RA. Decoding of risky choice demonstrates that cognitive control facilitates risk-seeking. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2470-5. doi: 10.1073/pnas.1321728111. Epub 2014 Feb 3. PMID: 24550270
  148. Sabb Fw, Hellemann G, Lau D, Vanderlan JR, Cohen HJ, Bilder RM, McCracken JT. High-Throughput Cognitive Assessment using BrainTest.org: Examining cognitive control in a family cohort. Brain and Behavior. 2013 Sep;3(5):552-61. doi: 10.1002/brb3.158. Epub 2013 Aug 2. PMID: 24392276
  149. Congdon E, Bato AA, Schonberg T, Mumford JA, Karlsgodt KH, Sabb Fw, London ED, Cannon TD, Bilder RM, Poldrack RA. Differences in neural activation as a function of risk-taking task parameters. Front Neurosci. 2013 Sep 30;7:173. doi: 10.3389/fnins.2013.00173. eCollection 2013. PMID: 24137106
  150. White CN, Congdon E, Mumford J, Karlsgodt KH, Sabb Fw, Freimer NB, London ED, Cannon TD, Bilder RM, Poldrack RA. Decomposing decision components in the Stop-signal task: A model-based approach to individual differences in inhibitory control. Journal of Cognitive Neuroscience. J Cogn Neurosci. 2014 Jan 9. [Epub ahead of print] PMID: 24405185
  151. Lenartowicz A, Delorme A, Walshaw PD, Cho AL, Bilder RM, McGough JJ, McCracken JT, Makeig S, Loo SK. Electroencephalography correlates of spatial working memory deficits in attention-deficit/hyperactivity disorder: vigilance, encoding, and maintenance. J Neurosci. 2014 Jan 22;34(4):1171-82. doi: 10.1523/JNEUROSCI.1765-13.2014. PMID: 24453310
  152. Congdon E, Altshuler LA, Mumford JA, Karlsgodt KH, Sabb FW, Ventura J, McGough JJ, London ED, Cannon TD, Bilder RM, Poldrack RA. Neural activation in adult ADHD participants during response inhibition: Effects of medication and symptom severity. Psychiatry Research: Neuroimaging, 2014. [in process] http://dx.doi.org/10.1016/j.pscychresns.2014.02.002
  153. McCarty CA, Huggins W, Aiello A, Bilder RM, Jernigan TL, Sanghera DK, Strauman TJ, Zeng Y, Ramos EM, Junkins HA, for the PhenX RISING network. PhenX RISING: Real World Implementation and Sharing of PhenX Measures. BMC Medical Genomics, 2014, 7:16 doi:10.1186/1755-8794-7-16.
  154. Parker DS, Congdon E, Bilder RM. Visualization of Variance in LA2K. BioData Mining. 2014 Jul 2;7:11. doi: 10.1186/1756-0381-7-11. PMID: 25097666
  155. Miller JB, Schoenberg M, Bilder RM. Consolidated Standards of Reporting Trials (CONSORT): Considerations for Neuropsychological Research. The Clinical Neuropsychologist. 2014 May;28(4):575-99. doi: 10.1080/13854046.2014.907445. PMID: 24766549.
  156. Bilder RM, Knudsen KS. Creative cognition and systems biology on the edge of chaos. Opinion, Front. Psychol. - Psychopathology, 2014, DOI: 10.3389/fpsyg.2014.01104; PMID: 25324809. RESEARCH PAPERS-PEER REVIEWED (IN PRESS)
  157. Wagshal D, Knowlton BJ, Cohen JR, Poldrack RA, Bookheimer SY, Bilder RM, and Asarnow RF. Impaired Automatization of a Cognitive Skill in First-Degree Relatives of Patients with Schizophrenia. Psychiatry Research.
  158. Twamley EW, Hua, J.P.Y., Burton, C.Z., Vella, L., Chinh, K., Bilder, R.M., & Kelsoe, J.R. (in press). Schizophr Res. 2014 Aug 16. pii: S0920-9964(14)00398-3. doi: 10.1016/j.schres.2014.07.041. [Epub ahead of print]
  159. Bilder RM, Sugar CA, Hellemann GS. Cumulative False Positive Rates Given Multiple Performance Validity Tests: Commentary on Davis and Millis (2014) and Larrabee (2014). (in press). The Clinical Neuropsychologist.
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