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Spring 2006

New Drugs Studied for Childhood Cancer

The new wave of molecularly targeted therapies that have proven successful in adults with cancer will be used to fight disease in children through a program offered at UCLA's Mattel Children's Hospital.
"We are building a program that brings the best in treatment to our pediatric patients," says Kathleen Sakamoto, M.D., chief of the UCLA division of pediatric hematology/oncology, who in her laboratory is testing several promising new compounds on pediatric cancer cell lines.
Agents that prove effective in fighting pediatric cancers will be tested in clinical trials run by Theodore Moore, M.D., clinical director of pediatric hematology/oncology. The first drug given the goahead for clinical trials is an agent that targets a mutated receptor in acute myeloid leukemia (AML). The clinical trials could begin before the end of the year.

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