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CARE Center  |  AIDS Institute

Research Studies & Clinical Trials

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Research Studies & Clinical Trials

A5401/ACTIV-2: A study to evaluate the safety and efficacy of investigational agents that could modifying the immune response to SARS-CoV-2 infection or limit disease progression

Enrollment Status: Closed

Overview/Purpose

We want to learn if study medications will prevent hospitalization and death in adults. This study looks at the safety and effectiveness of different drugs in treating COVID-19 in outpatients. Participants in the study will be treated with either a study drug or with placebo and will have 28 days of intensive follow-up following study drug administration, followed by limited follow-up through 24 weeks. Study visits may be required after week 24 depending on the study agent.

Interested in Volunteering?

To join, you must be:

  • 18 years or older
  • Have tested positive for COVID-19 within the past week
  • Experiencing at least one COVID-19 symptom, such as:
    • Fever
    • Cough
    • Shortness of breath
    • Sore throat
    • Body pain
    • Fatigue
    • Heacache

Principal Investigator:

Kara Chew, MD, MS

For more information, please contact the UCLA CARE Center:

[email protected]
424-440-3255

If you would prefer to have a community outreach coordinator or research coordinator reach out to you, please leave your contact information below and someone will reach out to you shortly.

 

Additional Resources:

  • actgnetwork.org/studies/a5401
  • activ-2.org/en
  • newswise.com/coronavirus/actg-announces-launch-of-novel-clinical-trial-testing-multiple-therapeutics-to-treat-covid-19
A5401 Photo
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