Stem Cell Therapy for Limbal Stem Cell Deficiency
This is a phase I open-label clinical study to determine the safety and feasibility of limbal stem cell therapy in patients that have been diagnosed with severe limbal stem cell deficiency. We will investigate the ability to manufacture and transplant the patient’s own stem cells onto the cornea and evaluate their ability to regenerate the ocular surface without serious adverse events.
For any questions, please contact the research team: LSCDtrial@mednet.ucla.edu
Investigator:Sophie X. Deng, MD, PhD
Clinical Trial to Evaluate the Safety and Efficacy of Corneal Collagen Cross-Linking of Keratoprosthesis Carrier Tissue in High-Risk Keratoprosthesis Implantation
This is a prospective, randomized, vehicle-controlled clinical trial evaluating corneal collagen cross-linking the keratoprothesis carrier tissue in subjects who are candidates for high-risk keratoprosthesis implantation because of a history of corneal melts, sterile corneal ulcers, or autoimmune diseases.
Investigators: Anthony J. Aldave, MD, and Sophie X. Deng, MD, PhD