Posted May 19, 2022
The Center for Neurobiology of Stress and Resilience in the Division of Digestive Diseases at the University of California Los Angeles is seeking a full time Post-Doctoral Research Fellow for a U54-funded project studying sex-related differences in the brain-gut-microbiome interactions related to visceral pain. This project is focused on the sex-specific effect of gut microbial metabolites, and estrogen levels on ascending arousal pathways originating in distinct brainstem nuclei to change the activity and connectivity of brain networks involved in symptom generation in irritable bowel syndrome.
As a part of an multidisciplinary research team the fellow will apply advanced computational, neuroimaging, biostatistical, and bioinformatics approaches to assess the interaction between various levels of biological data (e.g., microbiota, metabolites, sex hormones, multimodal brain and brainstem imaging data), clinical variables (symptom severity, widespread pain) and sex.
There will be opportunities to develop translational and clinical neuroscience research skills (e.g., target discovery, individualized treatment development and biomarker/predictor development), in addition to state-of-the-art analytical skills to address basic and pathophysiological systems biology questions.
The G Oppenheimer Center for Neurobiology of Stress and Resilience (CNSR) is an interdisciplinary, translational Center funded by the National Institutes of Health, and by philanthropic support. The overall research goals of the CNSR are to better understand the interactions between mind brain and body in health and disease, and to develop novel management strategies for optimal health and for complex chronic disorders.
Center investigators are conducting clinical, translational and basic research with human populations, using interventions (e.g., diet, cognitive behavioral therapy) alongside deep phenotyping including neuroimaging, mutli-omics profiling (gut microbiome, metabolomics, inflammatory biomarkers, psychosocial and behavioral assessments. You will work directly with Arpana “Annie” Gupta, PhD and Jennifer Labus, PhD and an array of faculty collaborators across UCLA, and beyond.
There will be many opportunities to lead high impact publications starting on day one, working with existing rich and unique datasets in addition to creating new ones. Extensive mentorship will be provided to facilitate the transition to an independent research career.
Duties and Responsibilities:
The Post-Doctoral Fellow’s responsibilities will include, but are not limited to:
Required Qualifications:
Preferred Qualifications:
Additional Information:
This is a 2 to 3-year term position with great opportunities for training in human systems biology, translational/clinical applications and diverse integrated methodologies. Expected start date: Summer/Fall 2022
The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what’s right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at https://medschool.ucla.edu/cultural-north-star.
As a condition of employment, you will be required to comply with the University of California SARS-CoV-2 (COVID-19) Vaccination Program Policy. All Covered Individuals under the policy must provide proof of Full Vaccination or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, and/or Religious Objection) or Deferral (based on pregnancy) no later than the applicable deadline. New University of California employees must (a) provide proof of receiving at least one dose of a COVID-19 Vaccine no later than 14 calendar days after their first date of employment and provide proof of Full Vaccination no later than eight weeks after their first date of employment; or (b) if applicable, submit a request for Exception or Deferral no later than 14 calendar days after their first date of employment. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.
To apply, please visit: https://recruit.apo.ucla.edu/JPF07513
Posted May 5, 2022
The Digestive Diseases in the Department of Medicine at the David Geffen School of Medicine is seeking applicants for a full-time Project Scientist position at the Assistant or Associate rank. The Microbiome Center is seeking candidates who can manage NIH, foundation, industry-sponsored or other patient-oriented research; assist in writing study protocols and coordinate, prepare, compile and review study materials; successfully recruit and interview potential research subjects. An M.D. or Ph.D. is required.
Duties include the following:
The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what’s right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at https://medschool.ucla.edu/cultural-north-star.
As a condition of employment, you will be required to comply with the University of California SARS-CoV-2 (COVID-19) Vaccination Program Policy. All Covered Individuals under the policy must provide proof of Full Vaccination or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, and/or Religious Objection) or Deferral (based on pregnancy) no later than the applicable deadline. New University of California employees must (a) provide proof of receiving at least one dose of a COVID-19 Vaccine no later than 14 calendar days after their first date of employment and provide proof of Full Vaccination no later than eight weeks after their first date of employment; or (b) if applicable, submit a request for Exception or Deferral no later than 14 calendar days after their first date of employment. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.
To apply, please visit: https://recruit.apo.ucla.edu/JPF07465
Posted May 3, 2022
The Division of Digestive Diseases in the Department of Medicine at the David Geffen School of Medicine at UCLA invites applications for a faculty position at the level of Instructor, Assistant, Associate, and full Professor ranks. The candidate must have a strong commitment towards expanding our current Inflammatory Bowel Disease (IBD) ambulatory and inpatient practice with interest in both clinical research and teaching students and trainees, including the development of an IBD fellowship program. The position involves participating at the Westwood site.
The candidate should have strong communication skills, a patient-centered approach to clinical care, and an interest in collaborating on scholarly activities. Preference will be given to those with previous experience in IBD care. Leadership opportunities will be available in clinical practice and education based on experience of the candidate. Applicants must be BC/BE Gastroenterologist with specialized expertise in IBD. Applicant must have an M.D./D.O. with completion of internal medical residency and gastroenterology fellowship from ACGME accredited program. We are seeking applicants who have had an extra fellowship year specializing in IBD.
The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what’s right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at https://medschool.ucla.edu/cultural-north-star.
All aspects of searches are confidential and all candidates are expected to review and abide by UC Regents Policy 1111 on Statement on Ethical Values and Standards of Conduct https://regents.universityofcalifornia.edu/governance/policies/1111.html.
As a condition of employment, you will be required to comply with the University of California SARS-CoV-2 (COVID-19) Vaccination Program Policy. All Covered Individuals under the policy must provide proof of Full Vaccination or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, and/or Religious Objection) or Deferral (based on pregnancy) no later than the applicable deadline. New University of California employees must (a) provide proof of receiving at least one dose of a COVID-19 Vaccine no later than 14 calendar days after their first date of employment and provide proof of Full Vaccination no later than eight weeks after their first date of employment; or (b) if applicable, submit a request for Exception or Deferral no later than 14 calendar days after their first date of employment. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.
To apply, please visit: https://recruit.apo.ucla.edu/JPF07421
Posted on December 8, 2021
The Vatche and Tamar Manoukian Division of Digestive Diseases at the David Geffen School of Medicine (DGSOM) at University of California at Los Angeles (UCLA) is seeking a highly regarded, established scientist and exceptional leader with the expertise and skills needed to be the Director of the Inflammatory Bowel Disease (IBD) Research Center and advance the distinguished research being conducted at UCLA.
Individuals interested in this position should have a M.D and/or Ph.D. degree (or equivalent), and a national/international reputation in the field of academic gastroenterology and/or immunology with a particular interest in IBD. Candidates must have a strong background in basic research in IBD-related themes (e.g., mucosal immunology) with emphasis on novel approaches, a record of accomplishment of extramural funding, and an excellent research and teaching record of accomplishments consistent with this position. Candidates should have a willingness to foster collaborative interactions between clinical and laboratory scientists, a strong interest in mentoring of junior faculty/fellows in our highly interactive academic and clinical environment, and a commitment to equity, diversity and inclusion.
The successful candidate will be appointed to a tenured position at the rank of Associate or Full Professor, considered for appointment to the Eli and Edythe L. Broad Foundation Chair in Inflammatory Bowel Disease Research, and equipped laboratory space commensurate with the leadership role this position will play in the division and David Geffen School of Medicine at UCLA.
The University of California seeks to recruit and retain a diverse workforce as a reflection of our commitment to serve the people of California, to maintain the excellence of the University, and to offer our students richly varied disciplines, perspectives and ways of knowing and learning. The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what’s right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at https://medschool.ucla.edu/cultural-north-star.
As a condition of employment, you will be required to comply with the University of California SARS-CoV-2 (COVID-19) Vaccination Program Policy. All Covered Individuals under the policy must provide proof of Full Vaccination or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, and/or Religious Objection) or Deferral (based on pregnancy) no later than the applicable deadline. New University of California employees must (a) provide proof of receiving at least one dose of a COVID-19 Vaccine no later than 14 calendar days after their first date of employment and provide proof of Full Vaccination no later than eight weeks after their first date of employment; or (b) if applicable, submit a request for Exception or Deferral no later than 14 calendar days after their first date of employment. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.
Interested applicants should submit their application online at: https://recruit.apo.ucla.edu/JPF06956
Posted on October 28, 2021
The Center for Neurobiology of Stress and Resilience in the Division of Digestive Diseases at the University of California Los Angeles is seeking a full time Post-Doctoral Research Fellow for an R01-funded project studying the brain-gut microbiome mechanisms of action underlying obesity. The Center is a multidisciplinary team conducting clinical, translational and basic research with human populations. The postdoctoral fellow will work directly with Dr. Arpana “Annie” Gupta, PhD and other faculty collaborators.
This project uses multimodal MRI sequences combined with measures of the gut microbiome and dimensional neuropsychiatric behavioral measures (i.e. tasks, questionnaires, heart rate variability, digital phenotyping, cognitive and clinical measures) to study structural and functional circuit dynamics in obesity.
There will be opportunities to develop translational and clinical research skills (e.g. target discovery, individualized treatment development and biomarker/predictor development), in addition to analysis methods and pipelines to address basic and pathophysiological systems biology questions. There will be many opportunities to lead high impact publications starting on day one. We will be working with existing unique datasets in addition to creating new ones. Extensive mentorship will be provided to facilitate the transition to an independent research career.
The Post-Doctoral Fellow’s responsibilities will include, but are not limited to:
Qualifications:
Additional Qualifications:
This is a 2 to 5-year term position with great opportunities for training in human systems biology, translational/clinical applications and diverse integrated methodologies.
As a condition of employment, you will be required to comply with the University of California SARS-CoV-2 (COVID-19) Vaccination Program Policy. All Covered Individuals under the policy must provide proof of Full Vaccination or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, and/or Religious Objection) or Deferral (based on pregnancy) no later than the applicable deadline. New University of California employees must (a) provide proof of receiving at least one dose of a COVID-19 Vaccine no later than 14 calendar days after their first date of employment and provide proof of Full Vaccination no later than eight weeks after their first date of employment; or (b) if applicable, submit a request for Exception or Deferral no later than 14 calendar days after their first date of employment. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.
To apply, please visit: https://recruit.apo.ucla.edu/JPF07020
Posted September 14, 2021
The Division of Digestive Diseases in the Department of Medicine at the David Geffen School of Medicine at UCLA are seeking applications for a full-time Postdoctoral position in the laboratory of Dr. Elizabeth Videlock. The focus of the Videlock Lab is on the role of the gut in Parkinson’s Disease. The Videlock Lab works with mouse models, human tissue and cell and enteroid cultures.
Specific techniques used in the lab include:
Responsibilities will include
The ideal candidate will have an interest in pursuing a project in this area and will be highly motivated to independently develop proficiency in experimental approaches and learn and implement new experimental techniques. While not required, an interest in the develop of script-based computational approaches to data analysis is preferred. A Ph.D., DVM, or M.D. is required.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.
To apply, please visit: https://recruit.apo.ucla.edu/JPF06888
Posted September 1, 2021
The Division of Digestive Diseases in the Department of Medicine at the David Geffen School of Medicine at UCLA and the VA Greater Los Angeles Health System are seeking applicants for a full-time Postdoctoral Scholar position in the Stress-Neurogastroenterology laboratory. The candidate will participate in projects involving anatomical profiling of neuronal circuits in the pelvic organs-autonomic nervous system, using tracing, immunohistochemistry, image reconstruction and molecular biology assays. The position will offer the candidate an excellent opportunity to advance their career path and to obtain training in new methodological approaches.
A PhD, DVM or MD is required with some experience and interest in neuroanatomical and immunohistochemical studies and in microscopy and imaging processing. Knowledge and experiences preferred in autonomic nervous system, microscopy, and image processing. The candidate must be enthusiastic, have strong written and oral communication skills, be highly motivated, intellectually creative, able to work independently, and function well as part of a team. Candidates will be expected to contribute to ongoing projects and expand novel independent research projects in a collaborative research environment.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.
To apply, please visit: https://recruit.apo.ucla.edu/JPF06860
Posted September 1, 2021
The laboratories of Drs. Guido Eibl in the Department of Surgery and Enrique Rozengurt in the Division of Digestive Diseases at the David Geffen School of Medicine are seeking applicants for a full-time Postdoctoral Scholar position. The proposed project is part of a recently funded 5-year NIH Program Project Grant on “Chemoprevention and mechanisms of obesity-promoted pancreatic adenocarcinoma (PDAC)”. Current projects focus on the role of YAP/TAZ transcriptional co-activators in diet-induced obesity and PDAC. These studies include investigating the underlying mechanisms that inflammation plays in the link between obesity and cancer, to identify the molecular mechanism, by which statins inhibit YAP/TEAD signaling in mouse and human pancreatic cells, and to characterize the inhibitory effect of statin and metformin on the development of PDAC as a novel chemopreventive strategy. Experiments are carried out in cell culture and genetically engineered mouse models. This position offers a unique opportunity to gain expertise in both signal transduction mechanisms in pancreatic cancer and a highly relevant preclinical model of this disease.
The candidate must be enthusiastic, have strong written and oral communication skills, be highly motivated, intellectually creative, able to work independently, and function well as part of a team. Candidates will be expected to contribute to ongoing projects and expand novel independent research projects in a collaborative research environment. A Ph.D, MD, or DVM is required.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.
To apply, please visit: https://recruit.apo.ucla.edu/JPF06874
Posted August 20, 2021
The Jacobs Laboratory in the UCLA Microbiome Center and the Division of Digestive Diseases, Department of Medicine at the David Geffen School of Medicine at UCLA, is seeking applicants for a post-doctoral position in microbiome science. The laboratory studies the role of intestinal microbes in inflammatory bowel disease (IBD) and other gastrointestinal diseases using a combination of multi-omics analysis of human cohorts to define microbiome-phenotype associations and in vivo models to elucidate underlying biological mechanisms.
The candidate will investigate the hypothesis that IBD-associated genetic variants disrupt pathways that regulate the intestinal microbiota, thereby creating a microbial pre-disease susceptibility state. This will be pursued through the use of gene edited and conditional knockout mice to model the effect of IBD-associated genetic variants on the microbiome. The relevance of these microbial shifts will be further investigated through the use of gnotobiotic mice colonized with human or mouse microbiota.
A PhD is required. Applicants must have extensive experience using animal models and molecular biology techniques in their prior scientific projects. Direct experience with microbiome research is welcome but not required. Prior bioinformatics exposure is not necessary.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.
To apply, please visit: https://recruit.apo.ucla.edu/JPF06806
Posted July 16, 2021
The Division of Digestive Diseases in the Department of Medicine at the David Geffen School of Medicine at UCLA invites applications for a faculty position at the level of Instructor, Assistant, Associate, and full Professor ranks. The position involves participating in gastroenterology practices located at various UCLA sites in Los Angeles County. Duties include direct patient care in the inpatient and outpatient setting and teaching medical students, residents, and fellows. An MD or DO is required. Applicants must be board eligible or board certified in Internal Medicine and board eligible or board certified in Gastroenterology. Active California medical license is required.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.
To apply, please visit: https://recruit.apo.ucla.edu/JPF06654
Posted July 2, 2021
The Division of Digestive Diseases in the Department of Medicine at the David Geffen School of Medicine at UCLA is seeking applicants for a faculty position at the Assistant, Associate or full rank. The position involves a minimum of 36 hours per week of direct patient care in the inpatient and outpatient setting. Duties include teaching medical students, residents, and fellows in the inpatient and outpatient settings and may include participating in gastroenterology practices located at various UCLA sites in Los Angeles County. Candidates must have Transplant Hepatology Certification and must be Board Certified or Board Eligible in Gastroenterology. An MD is required. Candidates must have a successful track record in clinical research.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.
To apply, please visit: https://recruit.apo.ucla.edu/JPF06583
