Clinical Trials

Research and Clinical Trials

Helpful Links

Information for Participants (UCLA OHRPP)
Understanding Clinical Trials (ClinicalTrials.gov)
UCLA Cancer Trials (UCLA JCCC)
Link to Non-Cancer Trials at UCLA

UCLA conducts research for a wide range of medical disorders and offers patients opportunities to participate in research and clinical trials.

Visit our Office of Clinical Trials website for more information about clinical trials.

Below are some featured trials at UCLA. Click here for a PDF of these trials. You may also visit the links to the right for additional trials from our clinical departments.


UCLA Aftercare Research Program

The Aftercare Research Program at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA will provide free treatment and assessment for participants in a clinical research study that is designed to improve the understanding of psychotic disorders and to develop more effective treatments. An initial diagnostic interview will determine a patient’s eligibility. The study will include individual case management, group therapy, and the antipsychotic medication risperidone. Family members of patients will be invited to join family psychoeducational meetings. An initial period on risperidone is a requirement of this study, so a change of medication may be needed.
Info: aftercare@mednet.ucla.edu, luana@ucla.edu or (310) 206-3142

A Woman's Own Words: Decisions About Hormonal Treatment After Breast Cancer

Women 65 years of age or older, who take or have taken hormonal treatment within the past 6 to 18 months are needed to participate in a research study to be interviewed about her experience with continuing or stopping a hormonal treatment such as Arimidex®, Aromasin® or Femara®. Participants will be interviewed for one to one-and-a- half hours by Huibrie Pieters, PhD, DPhil, RN. Receive $60 for your participation.
Info: (424)-241-0149

Child Anxiety Study

This UCLA Research Study conducted by Dr. Susanna Chang is investigating the usefulness of a novel computer-based attention training treatment for childhood anxiety. We are seeking help from children (ages 8 to 17) with social anxiety, generalized anxiety, and separation anxiety and their parents. Participation involves EEG recordings and eight weeks of a nonmedication attention training treatment for children. Parents of eligible participants are also asked to participate in similar attention training treatment to study how their participation may improve their child¹s anxiety.
Info: (310) 825-2064

Child Obsessive Compulsive Disorder Study

This UCLA Research Study conducted by Susanna Chang, MD, is investigating the usefulness of a novel computer-based attention training treatment for childhood OCD. We are seeking help from children ages 8 to 17 with OCD as study participants. Participation involves EEG recordings and four weeks of a non-medication attention training treatment.
Info: (310) 825-2064

Family Focused Treatment for Childhood OCD

Does your child have Obsessive Compulsive Disorder (OCD)? Does he/she: Have recurring thoughts that make no sense, but makes him/ her feel bad? Wash excessively or have fear of touching contaminated objects? Check and double-check more than necessary? Have to do things over and over again? This UCLA Research Study for kids and teens ages 8 to 17 with OCD is studying family involvement in non-medication Cognitive-Behavioral Therapy (CBT). Eligible participants will receive 14 weeks free treatment with Cognitive-Behavioral Therapy.
Info: (310) 206-1350

Cognitive Physiological Correlates of Anxiety in Youth

This UCLA research study is looking for child between the ages of 9 and 17 years. Participants must be healthy, speak English and live with their legal guardian. Participants will undergo a psychological evaluation. Two computer tasks and two problem solving tasks will be done to see how youths perceive and think about the world by studying the child’s heart rate and breathing. The study will take approximately three hours and requires one visit to UCLA. Please note that the study does not provide transportation to/from or parking at UCLA. This study is conducted by Michelle Rozenman, PhD and John Piacentini PhD at the UCLA Semel Institute for Neuroscience & Human Behavior.
Info: (310) 794-2215

Child Tic Disorders Study

This UCLA Research Study conducted by Sandra Loo, PhD, to investigate the relationship between brain waves and body movement among children with and without Chronic Tic Disorders. We are seeking help from families with children (ages 8 to 12) who are typically developing or have chronic tics. Participation in this one-visit study involves an interview with parent and child, cognitive assessments, questionnaires and an EEG to record electrical activity in the brain. Benefits of study participation include psychological and intelligence evolutions as well as up to $72 for parking and travel expenses.
Info: (310) 825-0122 or email mrasch@mednet.ucla.edu

Child Attention & Real-world Emotion Study

Does your child have frequent worries or fears? UCLA is recruiting children between the ages of 6 and 9 for a study about how attention may be related to the ability to manage emotions like anxiety or fear.

The research study involves questionnaires and interviews about you and your child’s mood and behaviors, computer tasks to see how kids process emotional information (like facial expressions), recording your child’s brain waves while they view emotional information and two weekends of short (5-10 minute) phone interviews about your child’s activities and emotions, as well as short (45-second) audio recordings of your child’s emotional expressions. The study involves two visits to our research laboratory (approximately three hours total) and two weekends of phone calls. We will also ask parents to complete a few questionnaires at 6 and 12 months following the last laboratory visit. Participants will receive compensation for their time and transportation costs; interested families may be provided with clinical referrals. There are no medical risks associated with this study.
Info: (310) 835-2701

Geriatric Depression

The UCLA Geriatric Psychiatry Program is conducting an early phase 12-week research study to compare the effects of two FDA-approved medications: Vilazodone and Paroxetine for the treatment of geriatric depression. This study is for those who are suffering from feelings of depression, sadness, hopelessness, memory loss, concentration difficulties, lack of energy, or loss of interest and pleasure in activities. All participants will be given the study drug, either Vilazodone or Paroxetine. A complete psychiatric evaluation will be provided. Subjects will not be charged for participation and will be compensated. Participants must be 60 years or older and experiencing symptoms of depression.
Info: (310) 983-3375 or (310) 794-4619

Late-life Depression

For those who are suffering from feelings of depression, sadness, hopelessness, memory loss, concentration difficulties, lack of energy, or loss of interest and pleasure in activities, UCLA is conducting a 12-month research study using an experimental combination of two drugs and a placebo (an inactive substance). If you are 60 years of age or older, not currently receiving any psychiatric treatment with effective medications, you may qualify. Medical and psychiatric evaluations and limited physical exams are provided as a part of the study. Participants will undergo a PET scan and an MRI scan. Evaluations and study drug are provided at no charge.
Info: (310) 983-3375 or (310) 794-4619

Study on Fitness and Memory

This project is designed to study the relationship between physical fitness, memory and the brain. People with memory complaints ages 60 to 89 are encouraged to participate. This study involves cognitive evaluations, brain MRIs and wearing activity monitors four times over the course of 18 months. Subjects will be compensated for participation and receive clinically relevant results of assessments.
Info: (310) 206-7392

Memory Enhancement Training or Yoga for Older Adults

For those who are suffering from memory loss, concentration difficulties, or lack of energy, UCLA is conducting a 6-month research study comparing a 60 minute weekly memory enhancement training course to yoga meditation. If you are 55 years of age or older and not currently receiving any psychiatric treatment, you may qualify. Medical and psychiatric evaluations and limited physical exams are provided as a part of the study. Participants will undergo two functional magnetic resonance imaging (fMRI) scans. A complete psychiatric evaluation will be provided. Participants will be compensated.
Info: (310) 794-9523 or (310) 794-4619

Treating Fibroids with Radiofrequency Energy

Researchers at the University of California, Los Angeles are conducting a study of a new FDA approved minimally invasive outpatient fibroid treatment called Acessa. If you have fibroids that cause heavy bleeding, pelvic pressure or any other significant symptoms, you may be eligible to participate. You will receive gift cards up to $180 for participation.
Info: (310)794-9652 or uclaobgynresearch@mednet.ucla.edu

SCOR Hormone Challenge

Do you suffer from Abdominal Pain and/or Discomfort, Constipation, or Diarrhea? Have you ever been told you have Irritable Bowel Syndrome (IBS)? Or, are you a Healthy Adult? If so, and you are between the ages of 18 and 55, you may qualify to participate in a UCLA research study conducted by Dr. Lin Chang. The purpose of this study is to compare certain components found in the saliva, blood, urine, and stool and responses to stressors between IBS patients and healthy adults. Eligible participants will complete 3 visits where they will undergo medical and psychological evaluations, fill out questionnaires, and provide saliva, blood, urine, and stool samples and complete two hormone challenge tests (i.e. Acthrel and Cortrosyn) and serial blood collections on separate days. Compensation is up to $250.
Info: (310) 206-1719 or uclacns.org

Pomegranate Juice Study

The UCLA Longevity Center is studying the effect of pomegranate juice on memory. Volunteers between the ages of 50 and 75 are needed. The study lasts one year and includes seven visits to UCLA and $300 compensation for participation.
Info: (310) 825-0545

Stroke / EDAS Revascularization for Intracranial Arterial Stenosis

Patients suffering strokes or transient ischemic attacks (TIA or mini-strokes) due to narrowing of the arteries of the brain may benefit from interventions to create new paths for the flow of blood to the brain. Medical management alone has been associated with very high risk of recurrent stroke and death. EDAS surgery is a form of minimally invasive management that can induce new vessel formation to bring additional blood flow to the brain preventing stroke.
Info: (310) 825-5154

Vulvodynia Research

UCLA researchers are seeking women ages 18 to 55 to help understand brain activity changes associated with a chronic pain condition called vulvodynia. Women who have been diagnosed with vulvodynia or vestibulodynia, or those with chronic pain around the opening of the vagina, may be eligible to participate. Participation includes a pelvic exam, sensitivity testing, and MRI scans. Volunteers can earn up to $130 for participating.
Info: (310) 825-5255 or uclaobgynresearch@mednet.ucla.edu


For more information about Clinical Trials offered to cancer patients, visit:
www.cancer.ucla.edu/clinical-trials or call UCLA jonsson Comprehensive Cancer Center (JCCC) Clinical Trials Hotline at (888) 798-0719.