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CARE Center  |  AIDS Institute

Research Studies & Clinical Trials

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Research Studies & Clinical Trials

New study for the treatment of latent CMV infection in HIV positive adults.

Enrollment Status: Open

Overview/Purpose

This is an open-label, controlled study, conducted at US sites to evaluate the anti-inflammatory effectiveness of the study drug letermovir in adults with HIV and asymptomatic cytomegalovirus (CMV) who are on antiretroviral therapy (ART)-mediated suppression. Participants will be randomly assigned to receive either letermovir once daily or no anti-CMV treatment, for 48 weeks.

Interested in Volunteering?

Do you want to participate in a study related to HIV & Aging? Explore a treatment that looks at whether an oral drug decreases inflammation.

Eligibility Criteria:

  • Age 40 or older
  • HIV with undetectable viral load on HIV treatment for at least 48 weeks
  • Positive for CMV (the study will perform the test)

  • Principal Investigator:

    Kara Chew, MD, MS

    For more information, please contact the UCLA CARE Center:

    [email protected]
    310-843-2015

    If you would prefer to have a community outreach coordinator or research coordinator reach out to you, please leave your contact information below and someone will reach out to you shortly.

 

Additional Resources:

  • Study Flyer
  • https://clinicaltrials.gov/ct2/show/NCT04840199
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