Open Actively Recruiting
Applying Best Clinical Practices to Patients at High Risk of Respiratory Complications
The purpose of this study is to:1. Perform a retrospective analysis on data contained in the UCLA Perioperative Data Warehouse on the incidence of respiratory dysfunction in the post-operative care unit (PACU) before and after the introduction of sugammadex into clinical practice. 2. Develop and implement a clinical best practice pathway designed to prevent postoperative respiratory complications in higher risk patients (such as those with OSA or preexisting respiratory disease) using education and clinical decision support in patients.
- UCLA Ronald Reagan or Santa Monica patients aged 18 and older who had a general anesthetic with either rocuronium or vecuronium.
- Patients who receive sugammadex from the specified study supply
- Patients under the age of 18
- Patients with a preoperative glomerular filtration rate less than 30 or on hemodialysis
- Patients with known hypersensitivity to any of the following: rocuronium, vecuronium, sugammadex, neostigmine or glycopyrrolate
- Patients with known neuromuscular disease
- Patients who remain intubated after surgery or leave the operating room with a tracheostomy in-situ
- Patients who did not receive reversal of neuromuscular blockade (with neostigmine in the pre-period or sugammadex in the post-period).
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