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Randomized Trial Comparing Performance of Molecular Markers for Indeterminate Thyroid Nodules

About

Brief Summary

The purpose of this study is to compare the performance of Afirma GSC and ThyroSeq v.3 in indeterminate thyroid nodules to determine which test can allow more patients to avoid unnecessary surgery and preserve quality of life. In the initial phase of this study, the performance of Afirma GEC and ThyroSeq v.2 were compared.

Study Type
Observational
Phase
N/A

Eligibility

Gender
All
Healthy Volunteers
No
Minimum Age
18 Years
Maximum Age
100 Years

Inclusion Criteria:

  • Patients with a thyroid nodule who have a thyroid biopsy performed at UCLA health will be eligible for the study and consented if they agree to participate.
  • Patients who have an indeterminate FNA biopsy result (Bethesda category 3 or 4) will be enrolled in the study if they agree to participate.

Exclusion Criteria:

  • Patients who do not have an indeterminate biopsy result (either patients who have a benign, insufficient, or malignant result).

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Study Stats
Protocol No.
16-000055
Category
Head and Neck Cancer
Survivorship
Contact
MASHA LIVHITS
Location
  • UCLA Westwood
For Providers
NCT No.
NCT02681328
For detailed technical eligibility, visit ClinicalTrials.gov.