Open Actively Recruiting

Secondhand Effects of E-Hookah Aerosol

About

Brief Summary

In the United States, exposure to secondhand smoke accounts for greater than 35,000 deaths annually from cardiovascular disease in never-smokers. Electronic (e-) hookahs are a new category of vaping devices gaining popularity among youth. While more is known on the acute effects of active hookah smoking and the literature is emerging on active e-hookah vaping, virtually nothing is known about the acute cardiovascular effects of secondhand exposure to e-hookah aerosol. The study aims to examine the acute effects of secondhand exposure of e-hookah aerosol on endothelial and vascular function. Eligible volunteers will be invited to participate in a total of 2 study visits (2-4 hours each): exposure to e-hookah aerosol delivered by a hookah smoking/vaping machine, and for comparison, before and after clean air. Non-invasive blood pressure and blood flow measurements will be taken before and after the exposure sessions.

Primary Purpose
Other
Study Type
Interventional
Phase
N/A

Eligibility

Gender
All
Healthy Volunteers
Yes
Minimum Age
21 Years
Maximum Age
35 Years

Inclusion Criteria:

  • 21-35 years old
  • Never a smoker: do not use any tobacco products or nicotine delivery systems, including cigarettes, cigars (traditional and filtered), cigarillos, hookah, smokeless tobacco (i.e., loose snus, moist snuff, dip, spit, or chewing tobacco), pipe tobacco, snus pouches, dissolvable tobacco or vaping.
  • no evidence of cardiopulmonary disease by history/physical
  • blood pressure (BP) < 140/90 mmHg
  • resting heart rate (HR) < 100 bpm
  • BMI >18 or < 30kg-m2
  • no prescription medication
  • No exposure to environmental tobacco smoke for at least one week prior to the study date.

Exclusion Criteria:

  • exhaled carbon monoxide >6 ppm
  • (+) pregnancy test
  • other conditions deemed unsafe to participate, such as breastfeeding

Join this Trial

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Study Stats
Protocol No.
20-001570
Category
School of Nursing
Principal Investigator
MARY REZK-HANNA
Contact
Byron Bustos
Location
  • UCLA Westwood
For Providers
NCT No.
NCT04661683
For detailed technical eligibility, visit ClinicalTrials.gov.