Secondhand Effects of E-Hookah Aerosol
In the United States, exposure to secondhand smoke accounts for greater than 35,000 deaths annually from cardiovascular disease in never-smokers. Electronic (e-) hookahs are a new category of vaping devices gaining popularity among youth. While more is known on the acute effects of active hookah smoking and the literature is emerging on active e-hookah vaping, virtually nothing is known about the acute cardiovascular effects of secondhand exposure to e-hookah aerosol. The study aims to examine the acute effects of secondhand exposure of e-hookah aerosol on endothelial and vascular function. Eligible volunteers will be invited to participate in a total of 3 study visits (2-3 hours each): e-hookah aerosol exposure, charcoal-heated hookah smoke exposure (both delivered by a hookah smoking/vaping machine) and smoke-free room air. Non-invasive blood pressure and blood flow measurements will be taken before and after the exposure sessions.
- 21-49 years old
- Never a smoker: do not use any tobacco products or nicotine delivery systems, including cigarettes, cigars (traditional and filtered), cigarillos, hookah, smokeless tobacco (i.e., loose snus, moist snuff, dip, spit, or chewing tobacco), pipe tobacco, snus pouches, dissolvable tobacco or vaping.
- no evidence of cardiopulmonary disease by history/physical
- blood pressure (BP) < 140/90 mmHg
- resting heart rate (HR) < 100 bpm
- BMI >18 or < 30kg-m2
- no prescription medication
- No exposure to environmental tobacco smoke for at least one week prior to the study date.
- exhaled carbon monoxide >6 ppm
- (+) pregnancy test
- other conditions deemed unsafe to participate, such as breastfeeding