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Beaven Laboratory
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Gupta Laboratory
Familial Mediterranean Fever Laboratory
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Hsiao Laboratory
Interventional Endoscopy Research
Jacob Laboratory
Jacobs Laboratory
Joshi Laboratory
Kaunitz Laboratory
Koon Laboratory
Limketkai Laboratory
May Laboratory
Mulugeta Laboratory
Patel Laboratory
Pisegna Laboratory
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Hsiao Laboratory
Hsiao Laboratory
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Key investigator
Elaine Y. Hsiao, PhD
Funding
NIH: NIMH, NIDDK, Common Fund
Department of Defense
Simons Foundation
Klingenstein Fund
Sloan Foundation
Brain Research Foundation
UCLA CURE
Current research projects
Uncovering microbial modulators of neuroactive molecules as novel therapeutics
Investigating microbiome effects on gene-environment interactions in neurological disease
Future research directions
Mechanisms underlying signaling between gut microbes and brain
Dietary effects on the gut microbiota and implications for neurological disease
Microbiome as regulators of host serotonin biosynthesis and neurodevelopment
Key publications -
Full list on PubMed
Agirman G, Yu KB,
Hsiao EY
. Signaling inflammation across the gut-brain-axis.
Science
. 2021 Nov 26;374(6571):1087-1092. doi: 10.1126/science.abi6087. Epub 2021 Nov 25
Vuong HE, Yano JM, Fung TC,
Hsiao EY
.
The microbiome and host behavior
.
Annual Review of Neuroscience
. doi: 10.1146/annurev-neuro-072116-031347 (2017)
Fung TC, Olson CA,
Hsiao EY
.
Interactions between the microbiota, immune and nervous systems
.
Nature Neuroscience
. 20:145-55 (2017)
Yano JM, Yu K, Donaldson G, Shastri G, Ma L, Ann P, Nagler C, Ismagilov RF, Mazmanian SK,
Hsiao EY.
Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis
,
Cell
, 161 : 264-276 (2015)
Hsiao EY.
Gastrointestinal issues in autism spectrum disorder
,
Harv Rev Psychiatry
, 22: 104-111 (2014)
Hsiao EY.
Immune dysregulation in autism spectrum disorder
,
Int Rev Neurobiol
, Konopka G., Harris A., Jenner P.(Eds.), 72 : 269-302 (2013)
Hsiao EY.
McBride SW, Hsien S, Sharon G, Hyde ER, McCue T, Codelli JA, Chow J, Reisman SE, Petrosino JF, Patterson PH*, Mazmanian SK,
The microbiota modulates behavioral and physiological abnormalities associated with neurodevelopmental disorders
,
Cell
, 155 : 1451-1463 (2013)
Hsiao EY
, Patterson PH.
Placental regulation of maternal-fetal interactions and brain development
,
Dev Neurobiol
, 72 : 1317-1326 (2012)
Hsiao EY
, McBride SW, Chow J, Mazmanian SK, Patterson PH.
Modeling an autism risk factor in mice leads to permanent immune dysregulation
,
PNAS
, 109 : 12776-12781 (2012)
Malkova NV, Yu CZ,
Hsiao EY
, Patterson PH.
Maternal immune activation yields offspring displaying the three core symptoms of autism
,
Brain Behav Immun
, 26 : 607-616 (2012)
Hsiao EY
, Bregere C, Malkova N, Patterson PH
Modeling features of autism in rodents, In: Autism Spectrum Disorders
, Amaral D.G., Dawson G., Geschwind D.H.(Eds.), 935-962 (2011) -
Pediatr Res
. 2011 May; 69(5 Pt 2): 34R–40R
Past GI research fellow
Tien A. Dong, MD, PhD (co-mentor with Jonathan P. Jacobs, MD, PhD)
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