The UCLA Pediatric Marfan Clinic offers evaluation and treatment of children and young adults suspected of having Marfan Syndrome (or other heritable connective tissue disorders). New patient evaluations include an echocardiogram of the heart and exam with Dr. Pererns. The Marfan and Aortopathy Clinic is on the 3rd Wednesday of every month. We provide regular evaluations and treatment of the aorta and heart, and work closely with ophthalmology, surgery, and orthopedics groups at UCLA.
UCLA Pediatric Ophthalmology at the Stein Eye Institute specializes in ocular (eyes) management for Marfan syndrome and related connective tissue disorders:
Simon Fung, MD - Pediatric Ophthalmology
The UCLA Medical Center offers evaluation and treatment of the spine, heart and chest:
Children's Heart Center
200 UCLA Medical Plaza, Suite 330
Los Angeles, CA 90024
Cardiology and Genetics care are provided at the Pediatric Cardiology offices and Ophthalmology (eyes) care at Jules Stein Eye Institute, across the street.
For an appointment, please call: Children's Heart Center (310) 267-7667
For an appointment with Ophthalmology, please call: Jules Stein Eye Institute (310) 794-9581
Young adults over the age of 21 are transitioned to the Adult Marfan Program within the UCLA Adult Congenital Heart Program. For an appointment, please call: UCLA-Adult Congenital Heart Disease Center (310) 825-9011
Children may be referred to evaluate for Marfan syndrome or a related connective tissue disorder for:
What is Marfan syndrome?
Marfan syndrome is a genetic disorder that affects the body's connective tissue. Connective tissue holds the body's cells, organs, and other tissue together. Connective tissue is also important in growth and development. Features of the disorder are most often found in the heart, blood vessels, bones, joints, and eyes.
What causes Marfan syndrome?
Marfan syndrome is caused by a defect (mutation) in the FBN1 gene. The FBN1 gene helps make a protein in connective tissue called fibrillin. The abnormal gene happens as follows:
What are the signs and symptoms of Marfan syndrome?