Researchers with Dr. Andrew Levine identified the factors leading to early-stage dementia in the Multicenter AIDS Cohort Study participants. The strongest predictors included the presence of clinical AIDS & hepatitis B or C infection.
Selection and subsequent modification of anti-seizure medication therapy in people with epilepsy can be complex. This systemic review by Dr. John Stern characterizes the effects of different anti-seizure medications are administered.
Can vagus nerve stimulation improve arm function after stroke? Dr. Steven Cramer & others find that vagus nerve stimulation paired with rehabilitation is a novel potential treatment option for people with arm impairment after ischemic stroke.
Drug Target Review reported on a new UCLA study led by Dr. S. Thomas Carmichael finding that a one-time injection of an experimental stem cell therapy can repair brain damage and improve memory function in mice with stroke and dementia.
A study by Drs. Irene Llorente and S. Thomas Carmichael was recently published in Science Translational Medicine. The findings suggested that astrocyte precursors have therapeutic potential in stroke.
The Neurology Journal of AAN published Dr. Bruce Dobkin's latest piece, "All in the Head: Facilitating Mental Imagery to Improve Mobility After Stroke".
Congratulations to the John Drug Discovery Lab on a new NIH RF1/R01 grant, titled "Small molecule mimetics of Humanin (HN) as novel therapeutic candidates for AD”.
Dr. Zeiger was awarded an K08 NINDS grant. The title of the grant is Mechanisms of Somatosensory Circuit Remapping after Cortical Injury in Mice.
Here, Drs. John Stern and Jerome Engel aimed to assess the association between hypometabolic extension of 18F-fluorodeoxyglucose PET and diffusion tensor imaging indices in hippocampal sclerosis.
The UCLA Drug Discovery Lab performed in vivo studies to determine if DDL-112 can reduce brain EV/exosome production and proteopathic alpha synuclein (aSyn) spread in a Parkinson's mouse model.