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Colorectal cancer
Ask the Doctors,
Cancer

Study looks at role of oral microbe in colorectal cancer

I recently read about a study that found a link between a certain kind of bacteria that lives in your mouth and the risk of developing colon cancer. I would like to know more details about that study, and also if this might point to a new approach in treatments.
April 24, 2024   |  
3 min read
PSA
Cancer,
Science & Research

Prostate cancer screenings encouraged for Black men as early as 40

New prostate screening guidelines organized by the Prostate Cancer Foundation aim to address the longstanding health disparity in prostate cancer: Black men are diagnosed with and die from prostate cancer at a much higher rate than white men.
April 24, 2024   |  
4 min read
3d rendered illustration - bladder cancer
Cancer,
Science & Research

FDA approves immunotherapy drug combo for non-muscle invasive bladder cancer after UCLA-led research shows improved outcomes for patients

The FDA approval was based on results of the QUILT 3.032 clinical trial, which was led by Dr. Karim Chamie, associate professor urology at the David Geffen School of Medicine at UCLA and a researcher at the UCLA Health Jonsson Comprehensive Cancer Center.
April 23, 2024   |  
3 min read
DNA
Cancer,
Science & Research

Mutations in noncoding DNA become functional in some cancer-driving genes

UCLA researchers, using an experiment that elucidated the function of tens of thousands of noncoding variants, discovered a link between functional mutations and genes linked to cancer pathways, as well as indicators to predict cancer patient survival.
April 18, 2024   |  
5 min read
Conway, Damoiseaux, Lo and Yang.
Cancer,
Science & Research

Cancer researchers receive Team Science Award from Melanoma Research Alliance

The award supports the team’s research in improving a small molecule to break down PD-L1 more effectively and identifying other PD-L1-degrading small chemical compounds.
April 16, 2024   |  
2 min read
Joseph de Rutte/UCLA
Cancer,
Science & Research

Advance in immune cell screening uncovers receptors that target prostate cancer

A recent UCLA study demonstrates a new process for screening T cells, part of the body’s natural defenses, for characteristics vital to the success of cell-based treatments.
April 15, 2024   |  
4 min read
Beth Karlan
Cancer

Dr. Beth Karlan named NCCN Guidelines Steering Committee Chair

In this role, Karlan, director of cancer population genetics at the UCLA Health Jonsson Comprehensive Cancer Center, is responsible for overseeing the development, maintenance, and dissemination of clinical practice guidelines for cancer care.
April 12, 2024   |  
2 min read
Dr. Matthew Rettig
Cancer,
Science & Research

Dr. Matthew Rettig recognized by VA for contributions to prostate cancer research

The award recognizes Rettig’s commitment to improving health care for veterans, as well as his scientific leadership. Along with the honor, Rettig will receive $150,000 over the next three years in research support.
April 11, 2024   |  
2 min read
Breast cancer exam
Cancer,
Science & Research

Black women with breast cancer are less likely than white women to undergo preventative removal of the unaffected breast

Black women with cancer in one breast are less likely than white women to undergo contralateral prophylactic mastectomies (CPM), a procedure to remove the unaffected breast, which women often choose for deeply personal reasons.
April 11, 2024   |  
3 min read
Dr. Antoni Ribas
Cancer,
Science & Research

Researchers receive $10.2 million from CIRM to advance CAR T-cell therapy for aggressive cancers

The award supports the team’s work investigating a new immunotherapy treatment using CAR T-cells to treat patients whose tumors express a protein called IL13Ra2.
April 10, 2024   |  
2 min read
pancreatic cancer
Cancer,
Science & Research

AACR: Preliminary study finds immunotherapy combination before surgery improves outcomes for patients with pancreatic cancer

A pilot study led by UCLA investigators suggests that for people with borderline resectable pancreatic cancer, administrating an immunotherapy drug in combination with chemotherapy before surgery is safe and may improve long-term outcomes.
April 5, 2024   |  
4 min read
Man pointing at flat computer monitor screen
Cancer,
Science & Research

For genomic sequencing needs, researchers turn to UCLA Health

The Technology Center for Genetics and Bioinformatics provides comprehensive bulk, single-cell and spatial sequencing to help advance biological research.
April 1, 2024   |  
5 min read
John K. Lee
Cancer,
Science & Research

Cancer researcher elected to American Society for Clinical Investigation

Dr. John Lee, associate assistant professor in residence of hematology/oncology in the David Geffen School of Medicine at UCLA, has been elected as a member of the American Society for Clinical Investigation.
April 1, 2024   |  
1 min read
HERSTORY
Cancer,
Science & Research

HERSTORY: Democratizing cancer genetic testing to reduce healthcare disparities

Researchers in the UCLA Health Jonsson Comprehensive Cancer Center have launched a new study aimed at unraveling inherited genetic predispositions to cancer in women with a family history of the disease.
March 27, 2024   |  
3 min read
T cells
Cancer,
Science & Research

Genetically engineered dendritic cells enhance the power of immunotherapy against lung cancer

A UCLA Health study suggests that using CXCL9 and CXCL10-producing dendritic cells alongside immunotherapy can be a promising strategy to overcome treatment resistance and improve clinical outcomes for patients with non-small cell lung cancer.
March 26, 2024   |  
3 min read
epigenetics
Cancer,
Science & Research

AACR: Progress treating pancreatic cancer, immunotherapy for head and neck cancers, potential biomarker for aggressive neuroendocrine carcinomas and more

The annual ACCR meeting will feature the latest research from UCLA physicians and scientists, who will present their latest findings in key areas of translational and basic scientific research.
March 25, 2024   |  
6 min read
Prostate cancer cells
Cancer

Theranostics treatments for cancer underway at UCLA Health

Targeted radioactive drugs are used to treat patients with advanced prostate, thyroid and neuroendocrine cancer.
March 20, 2024   |  
5 min read