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Microbiome

New UCLA-led research suggests certain gut bacteria -- including one that is essential for a healthy gut microbiome – differ between people who go on to acquire HIV infection compared to those who have not become infected.

COVID vaccine vial and needle

Women with COVID in pregnancy who are subsequently vaccinated after recovery, but prior to delivery, are more likely to pass antibodies on to the child than similarly infected but unvaccinated mothers are.

Fluorescent imaging of diverse cell types in a human brain section.

The research projects, funded through the NIH's BRAIN Initiative, aim to shed light on the developing brain’s cellular infrastructure to better understand brain disorders.   

Heroin needle in the street

An automated process that combines natural language processing and machine learning identified people who inject drugs (PWID) in electronic health records more quickly and accurately than current methods that rely on manual record reviews.

COVID vaccine vial and needle

The David Geffen School of Medicine at UCLA has been awarded a $13.6 million grant from the Centers for Disease Control and Prevention to continue to study the effectiveness of COVID-19 vaccines and the long-term impact of infection among U.S. health care workers.

Tax Form

UCLA research finds that a refundable State-level Earned Income Tax Credit (SEITC) of 10% or above the Federal EITC was associated with a 21% relative risk reduction in reported behavior that could put single mothers at high risk for becoming infected with HIV during the previous year. Also, a 10 percentage-point increase in SEITC was linked to a 38% relative reduction in the same reported high-risk behavior the previous year. 

Fentanyl

An automated process based on computer algorithms that can read text from medical examiners’ death certificates can substantially speed up data collection of overdose deaths – which in turn can ensure a more rapid public health response time than the system currently used, new UCLA research finds.

Microscope and slide

How independent are second opinions when information is shared between physicians? To find out, a UCLA-led team of researchers examined how pathologists tasked with offering a second opinion for a patient might be influenced by being informed of the first physician’s initial diagnosis. The results were eye-opening. While pathologists and most physicians may prefer to have information from a first diagnosis, this information can sway their evaluations and even make them less accurate.

Doctors performing Transplant

The Dumont–UCLA Transplant Center has received two grants totaling $11.5 million from the federal government for research aimed at making donated organs last longer and helping transplant recipients live longer, healthier lives.

COVID Image

Emergency department health care workers’ risk of infection in the early stages of the SARS-CoV-2 (COVID-19) pandemic was largely related to household and other community exposures and not from providing direct patient care while using recommended personal protective equipment (PPE). 

Illustration of young woman performing a calculation

The inaugural cohort of innovators has been selected to participate in UCLA Health’s new TechQuity Accelerator. The class represents pre-seed through Series A-stage companies that are championing health equity-driven innovations across the life sciences, spanning the medical device, digital health, diagnostic, and biopharma sectors. 

Tired doctor

A commonly used behavioral intervention—informing primary care physicians about how their performance compares to that of their peers—has no statistically significant impact on preventive care performance. It does, however, decrease physicians’ job satisfaction while increasing burnout.

Prescription pills

Outpatient antibiotic management of selected patients with appendicitis is safe, allowing many patients to avoid surgery and hospitalization, and should be considered as part of shared decision-making between doctor and patient.

T-cell infected with HIV

HIV has an “early and substantial” impact on aging in infected people, accelerating biological changes in the body associated with normal aging within just two to three years of infection.

Medicare Enrollment Form

Medicare could waste up to $605 million per year on the controversial Alzheimer’s drug aducanumab if it is eventually approved for widespread use because it is supplied in vials containing fixed doses that may not be appropriate for all patients–resulting in the trashing of large volumes of unused drug.

Spencer Zack Currier

The UCLACharles R. Drew University of Medicine and Science Center for AIDS Research has received a five-year, $11 million grant from the National Institutes of Health. A priority of the award is to fund research addressing health inequities that have fueled the spread of HIV in marginalized communities.  

Doctor working with computer interface

The UCLA Center for SMART Health, an interdisciplinary collaborative that looks to the integrated transformation of healthcare through emergent data and technologies, and Hearst Health, a division of Hearst and leader in care guidance, today announced the call for submissions is open for the 2022 Hearst Health Prize, a $100,000 award given in recognition of excellence in data science for managing or improving health in the U.S. In addition, up to two finalists will each receive $25,000.

Medical School Students

In states with bans on affirmative action programs, the proportion of students from underrepresented racial and ethnic minority groups in U.S. public medical schools fell by more than one-third by five years after those bans went into effect.

CCR5 with membrane

A UCLA-led team of researchers studying the effect of the monoclonal antibody Leronlimab on long COVID-19 may have found a surprising clue to the baffling syndrome, one that contradicts their initial hypothesis.  An abnormally suppressed immune system may be to blame, not a persistently hyperactive one as they had suspected.

COVID-19

New UCLA research finds that 30% of people treated for COVID-19 developed Post Acute Sequelae of COVID-19 (PASC), most commonly known as “Long COVID.” Of the 309 people with long COVID studied, the most persistent symptoms were fatigue and shortness of breath (31% and 15%, respectively) in hospitalized persons, and loss of sense of smell (16%) in outpatients.