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Higher levels of a key inflammatory marker were related to older breast cancer survivors reporting cognitive problems, according to UCLA-led research.
New UCLA-led research suggests certain gut bacteria -- including one that is essential for a healthy gut microbiome – differ between people who go on to acquire HIV infection compared to those who have not become infected.
Researchers at UCLA’s Jonsson Comprehensive Cancer Center and collaborating organizations report successful results from an experimental cancer-detection system that appears to have overcome some of the challenges of the "liquid biopsy" in a novel, cost-effective way.
The National Cancer Institute has renewed funding for two collaborative programs through which UCLA Jonsson Comprehensive Cancer Center researchers are developing new biomarkers for earlier detection and more effective treatment of cancers. The grants are part of the NCI's Early Detection Research Network.
Women with COVID in pregnancy who are subsequently vaccinated after recovery, but prior to delivery, are more likely to pass antibodies on to the child than similarly infected but unvaccinated mothers are.
The research projects, funded through the NIH's BRAIN Initiative, aim to shed light on the developing brain’s cellular infrastructure to better understand brain disorders.
An automated process that combines natural language processing and machine learning identified people who inject drugs (PWID) in electronic health records more quickly and accurately than current methods that rely on manual record reviews.
A previously unobserved relationship between body temperature and REM sleep suggests that REM sleep may act as a "thermostatically controlled brain heater."
The UCLA Clinical AIDS Research and Education (CARE) Center today announced its participation in STOMP (Study of Tecovirimat for Human Monkeypox Virus), or A5418, a phase 3, randomized, placebo-controlled, double-blind trial evaluating the safety and efficacy of tecovirimat for the treatment of human monkeypox.
The David Geffen School of Medicine at UCLA has been awarded a $13.6 million grant from the Centers for Disease Control and Prevention to continue to study the effectiveness of COVID-19 vaccines and the long-term impact of infection among U.S. health care workers.
Analyzing genetic ancestry data from a large genomic repository – the UCLA ATLAS Precision Health Biobank – researchers have found a highly diverse patient population that’s consistent with the global diversity of Los Angeles – one of the most ethnically diverse cities in the world and an ideal location to pursue personalized, precision medicine for underrepresented populations.
UCLA researchers report a step forward in the development of an “off-the-shelf” cell therapy that could reduce the severity of graft-versus-host disease in people receiving donor bone marrow transplants for the treatment of blood cancers such as leukemia and lymphoma.
Acute and late grade 2 GU toxicities were both 9%, while acute and late grade 2 GI toxicities were 5% and 0%. Three patients had grade 3 toxicity (1 GU and 2 GI). No patients receiving MRgRT had grade 3 GU or GI toxicity above grade 2.
UCLA research finds that a refundable State-level Earned Income Tax Credit (SEITC) of 10% or above the Federal EITC was associated with a 21% relative risk reduction in reported behavior that could put single mothers at high risk for becoming infected with HIV during the previous year. Also, a 10 percentage-point increase in SEITC was linked to a 38% relative reduction in the same reported high-risk behavior the previous year.
The pilot study is one of the first to indicate that neurofeedback could help address cognitive deficits of cancer patients experiencing “chemo brain."
In single pollutant models and within a 20-year period, 10 out of 29 reviewed pesticides were associated with thyroid cancer, including several of the most widely used ones in the U.S. These included paraquat dichloride, glyphosate and oxyfluorfen.
Identifying the causal variants and the genes they impact is a major challenge in modern genetics and biomedicine. This study provides an efficient roadmap for tackling this problem.
A warming planet doesn’t just mean more people may find it harder to get quality sleep. There is also evidence suggesting that sleep disturbance could make it harder for the body to fend off infection.
An automated process based on computer algorithms that can read text from medical examiners’ death certificates can substantially speed up data collection of overdose deaths – which in turn can ensure a more rapid public health response time than the system currently used, new UCLA research finds.
How independent are second opinions when information is shared between physicians? To find out, a UCLA-led team of researchers examined how pathologists tasked with offering a second opinion for a patient might be influenced by being informed of the first physician’s initial diagnosis. The results were eye-opening. While pathologists and most physicians may prefer to have information from a first diagnosis, this information can sway their evaluations and even make them less accurate.