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Fentanyl

An automated process based on computer algorithms that can read text from medical examiners’ death certificates can substantially speed up data collection of overdose deaths – which in turn can ensure a more rapid public health response time than the system currently used, new UCLA research finds.

Microscope and slide

How independent are second opinions when information is shared between physicians? To find out, a UCLA-led team of researchers examined how pathologists tasked with offering a second opinion for a patient might be influenced by being informed of the first physician’s initial diagnosis. The results were eye-opening. While pathologists and most physicians may prefer to have information from a first diagnosis, this information can sway their evaluations and even make them less accurate.

Doctors performing Transplant

The Dumont–UCLA Transplant Center has received two grants totaling $11.5 million from the federal government for research aimed at making donated organs last longer and helping transplant recipients live longer, healthier lives.

COVID Image

Emergency department health care workers’ risk of infection in the early stages of the SARS-CoV-2 (COVID-19) pandemic was largely related to household and other community exposures and not from providing direct patient care while using recommended personal protective equipment (PPE). 

Tired doctor

A commonly used behavioral intervention—informing primary care physicians about how their performance compares to that of their peers—has no statistically significant impact on preventive care performance. It does, however, decrease physicians’ job satisfaction while increasing burnout.

Prescription pills

Outpatient antibiotic management of selected patients with appendicitis is safe, allowing many patients to avoid surgery and hospitalization, and should be considered as part of shared decision-making between doctor and patient.

T-cell infected with HIV

HIV has an “early and substantial” impact on aging in infected people, accelerating biological changes in the body associated with normal aging within just two to three years of infection.

Medicare Enrollment Form

Medicare could waste up to $605 million per year on the controversial Alzheimer’s drug aducanumab if it is eventually approved for widespread use because it is supplied in vials containing fixed doses that may not be appropriate for all patients–resulting in the trashing of large volumes of unused drug.

Spencer Zack Currier

The UCLACharles R. Drew University of Medicine and Science Center for AIDS Research has received a five-year, $11 million grant from the National Institutes of Health. A priority of the award is to fund research addressing health inequities that have fueled the spread of HIV in marginalized communities.  

Medical School Students

In states with bans on affirmative action programs, the proportion of students from underrepresented racial and ethnic minority groups in U.S. public medical schools fell by more than one-third by five years after those bans went into effect.

CCR5 with membrane

A UCLA-led team of researchers studying the effect of the monoclonal antibody Leronlimab on long COVID-19 may have found a surprising clue to the baffling syndrome, one that contradicts their initial hypothesis.  An abnormally suppressed immune system may be to blame, not a persistently hyperactive one as they had suspected.

COVID-19

New UCLA research finds that 30% of people treated for COVID-19 developed Post Acute Sequelae of COVID-19 (PASC), most commonly known as “Long COVID.” Of the 309 people with long COVID studied, the most persistent symptoms were fatigue and shortness of breath (31% and 15%, respectively) in hospitalized persons, and loss of sense of smell (16%) in outpatients.

Drugs

The rate of overdose deaths among U.S. teenagers nearly doubled in 2020, the first year of the COVID pandemic, and rose another 20% in the first half of 2021 compared with the 10 years before the pandemic, even as drug use remained generally stable during the same period. This is the first time in recorded history that the teen drug death rate has seen an exponential rise

E-scooter crash

For a recent six-year period, the injury rate for riders of electric scooters in one section of Los Angeles was higher than the national rates for riders of motorcycles, bicycles and cars, and pedestrians, new UCLA research has found.

Osteoporosis in spine

Physicians may be able to determine if menopause-related bone loss is already in progress or about to begin by measuring the level of a hormone that declines as women approach their final menstrual period. The findings could help physicians determine when, and how, to treat bone loss in women as they age before that bone loss causes significant health issues,

Newsroom default

Dr. Carol Mangione, Barbara A. Levey M.D., and Gerald S. Levey, M.D., Endowed chair in medicine and chief of the UCLA Division of General Internal Medicine and Health Services Research, has been named chair of the U.S. Preventive Services Task Force (USPSTF).

HIV positive blood sample

The National Institute of Mental Health has renewed its support for UCLA’s collaborative Center for HIV Identification, Prevention and Treatment Services, or CHIPTS, with a five-year, $7.5 million grant.

 

An older person's hand being held

The Dementia Care Study (D-CARE), a nation-wide clinical trial assessing the effectiveness of different approaches to caring for people with Alzheimer’s disease and other dementias, has reached its recruitment goal by enrolling 2,176 persons living with dementia and their caregivers.

Visualization of the COVID 19 virus

In a new report, researchers say the challenges of treating long COVID are amplified by a critical issue: we do not know what constitutes long COVID or how to formally diagnose it, an issue that is further exacerbated by limited research data of varying quality and consistency.

Hands holding prescription drugs

In 2020, the first year of the COVID-19 pandemic, the rate of drug overdose deaths among Black Americans surpassed that of whites for the first time since 1999 — a sharp reversal of the situation a decade earlier, when rates were twice as high for whites as for Blacks. Native Americans/Alaska Natives experienced the highest overdose death rate in 2020 and were, along with Blacks and Latinos, among the groups with the largest increase in overdose deaths per 100,000 people over the previous year. Death rates for all four racial and ethnic groups studied, including whites, not only climbed in 2020 but climbed higher than in any single year prior.