Karren Takamura, MD
Home town: Los Angeles
Interests/Hobbies: Soccer, College football, Tacos, Classical music, Reading

EDUCATION
Undergraduate: University of Southern California
Medical School: David Geffen school of Medicine at UCLA
Internship: General Surgery, David Geffen School of Medicine at UCLA
Residency: Orthopedic Surgery, David Geffen School of Medicine at UCLA
Fellowship: Brigham and Women’s Harvard Hand/Upper Extremity Fellowship

RESEARCH INTEREST
Hip arthroplasty, metal-on-metal, hip resurfacing, outcomes of hip arthroplasty

PUBLICATIONS
PA Campbell, KM Takamura, W Lundergan, C Esposito, HC Amstutz. “Cement Technique Changes Improved Hip Resurfacing Longevity:  Implant Retrieval Findings.” Bull NYU Hosp Jt Dis. 2009;67 (2):146-53.

PA Campbell, S Nelson, E Ebramzadeh, KM Takamura, K De Smet, HC Amstutz. “Histological Feature of Pseudotumor-like Tissues from Metal-on-Metal Hips” Clin Orthop Rel Res., 2010; 468(2): 2321-2327

HC Amstutz, KM Takamura, M Le Duff “The effect of patient selection and surgical technique on results of Conserve Plus hip resurfacing: 3 to 14 year follow up.” Orthop Clin North Am. 2011 Apr; 42(2):133-42.

HC Amstutz, M Le Duff, P Campbell, L Wisk, KM Takamura “Complications after metal-on-metal hip resurfacing Arthroplasty.” Orthop Clin North Am. 2011 Apr; 42(2):207-30.

E Ebramzadeh, PA Campbell, KM Takamura, Z Lu, HC Amstutz, K De Smet “Failure modes of 433 metal-on-metal hip implants: how, why, wear.” Orthop Clin North Am. 2011 Apr; 42(2):241-50.

KM Takamura, J Yoon, E Ebramzadeh, PA Campbell, HC Amstutz. “The incidence of neck narrowing in Conserve Plus series of the first 500 hips.” Orthop Clin North Am. 2011 Apr; 42(2):181-93.

JP Yoon, M Le Duff, KM Takamura, S Hodge, H Amstutz. “Mid-to-long term follow-up of Transcend metal-on-metal versus Interseal metal-on-polyethylene bearings in total hip arthroplasty” Hip Int. 2011; 21(05):571-576.

JP Yoon, A Johnson, M Le Duff, KM Takamura, E Ebramzadeh, HC Amstutz. “Contact patch to rim distance predicts metal ion levels in hip resurfacing.” Clin Orthop Rel Res., 2013. 471 (5): 1615-1621.

KM Takamura, HC Amstutz, PA Campbell, Z Lu, E Ebramzadeh. “Wear analysis of 39 Conserve Plus metal-on-metal hip resurfacing retrievals.” Journal of Arthroplasty.  2013. 29 (2): 410-415.

M Al-Hamad, MJ Le Duff, KM Takamura, HC Amstutz. “Acetabular component thickness does not affect mid-term clinical results.” Clin Orthop Rel Res., 2014 May; 472(5): 1528-34.

KM Takamura, P Maher, T Nath, EP Su. “Survivorship of standard vs. modified posterior surgical approaches in metal-on-metal hip resurfacing arthroplasty.” Bone Joint Res. 2014 May; 3(5): 150-4. 

HC Amstutz, KM Takamura, E Ebramzadeh, M LeDuff. “Highly cross-linked polyethylene in hip resurfacing arthroplasty. Long-term follow-up.” Hip Int. 2015 Jan-Feb; 25(1): 39-43.

TL Tan, MJ LeDuff, KM Takamura, HC Amstutz. “Do clinical and quality of life scores change over time after hip resurfacing?” Hip Int. 2015 Mar-Apr; 25(2):146-51.

KM Takamura, Chen JB, Petrigliano FA. “Nonarthroplasty options for the athlete or active individual with shoulder osteoarthritis.” Clin Sports Med. 2018 Oct; 37(4): 517-526.

JJ Beck, KM Takamura, JM Beck, RE Bowen. “Hamstring autograft too small: how much allograft do you need to supplement to a desired hybrid graft size?” Arthroscopy. 2019 Feb; 35(2): 530-534.

JJ Beck, KM Takamura, JM Beck, RE Bowen. “Iliotibial band autograft: what size is the graft? A mathematical and cadaveric model: ITB single and double strand size.” Arch Orthop Trauma Surg. 2019, May 25.

PA Campbell, KM Takamura. “Local and systemic consequences of metal-on-metal hip resurfacing implants”. Annals of Joint. Accepted 2019.

BOOK CHAPTERS
Campbell, PA and KM Takamura (2012). Biologic responses to metal wear debris and ions. Surgery of the Hip. D Berry and JR Lieberman. New York, Elsevier: 171-181.

Campbell, PA and KM Takamura (2008). Reaction to wear products. Hip Resurfacing Principles, Indications, Technique and Results. H. C. Amstutz. Philadelphia, Saunders Elsevier: 133-148.

Takamura, KM and FA Petrigliano (2019). The ethical approval process. Basic Methods Handbook for Clinical Orthopaedic Research. V Musahl, J Karlsson, M Hirschmann, O Ayeni, R Marx. Philadelphia, Springer: 75-81.

KM Takamura, PA Campbell, N Frisch, J Jacobs (2019). Biologic responses to metal debris and metal ions. Surgery of the Hip, Second edition. D. Berry and JR Lieberman. Philadelphia, Saunders Elsevier: 113-127.

ABSTRACTS, POSTERS, PRESENTATIONS
KM Takamura. “Seeing the power struggle between doctors, lawyers, and patients from a Foucauldian point of view- a need for medical liability reform.” 5th International Conference on Ethical Issues in Biomedical Engineering. Brooklyn, New York. April 3-5, 2009. Podium presentation.

PA Campbell, S Nelson, C Esposito, KM Takamura, K De Smet. “Soft Tissue Histology around Metal-on-Metal Hips.” American Academy of Orthopaedic Surgeons Annual Meeting poster No. ORS 1. Las Vegas, NV. Feb 25-28, 2009.

PA Campbell, S Nelson, C Esposito, KM Takamura, K De Smet. “Soft tissue histology around metal-on-metal hips” The Annual Meeting of the Orthopaedic Research Society poster # 2269, Las Vegas, NV Feb 22-25 2009

KM Takamura “Seeing the power struggle between doctors, lawyers, and patients from a Foucauldian point of view- a need for medical liability reform.” Journal of Long-Term Effects of Medical Implants 2009; Vol 18 (1): 98. Abstract only.

AK Battenberg, PA Campbell, KM Takamura. “Solid corrosion products in metal-metal hip tissues: implications for metal sensitivity?” Journal of Investigative Medicine, Vol. 58 (1), #464, January 2010. Abstract only.

PA Campbell, KM Takamura, AK Battenberg, E. Ebramzadeh. S. Nelson. “Clinical consequences of CoCr wear products in the hip.” American Society of Materials International: Materials and Processes for Medical Devices Conference.

AK Battenberg, KM Takamura, PA Campbell, S Nelson. “Solid corrosion products in metal-metal hip tissues: implications for metal sensitivity?” The Annual Meeting of the Orthopaedic Research Society poster #2337. New Orleans, LA Mar. 6-9, 2010.

PA Campbell, KM Takamura, S Nelson. “Histological features of femoral hip resurfacings with neck narrowing.” The Annual Meeting of the Orthopaedic Research Society poster #2354. New Orleans, LA. Mar 6-9, 2010.

HC Amstutz, KM Takamura, M Le Duff. “Metal-on-metal hip resurfacing in ideal candidates- 3 to 13 year follow-up.” The 74th Annual Meeting of the Western Orthopaedic Association. Monterey, California. August 4-7, 2010.

HC Amstutz, KM Takamura, M Le Duff. “Metal-on-metal hip resurfacing in ideal candidates- 3 to 13 year follow-up.” 2010 Meeting of the Hip Society Summer Scientific Meeting (Closed). Hospital for Special Surgery, New York, NY. September 23-25, 2010.

HC Amstutz, KM Takamura, PA Campbell, Z Lu, E Ebramzadeh. “In vivo wear analysis of 29 Conserve Plus® metal-on-metal hip resurfacings and relationship with ‘adverse local tissue reaction’.” 2010 Meeting of the Hip Society Summer Scientific Meeting (Closed). Hospital for Special Surgery, New York, NY. September 23-25, 2010.

HC Amstutz, KM Takamura, PA Campbell, Z Lu, E Ebramzadeh. “In vivo wear analysis of 29 Conserve Plus® metal-on-metal hip resurfacings and relationship with ‘adverse local tissue reaction’.” American Association of Hip and Knee Surgeons 20th Annual Meeting. Dallas, TX. November 5-10, 2010.

KM Takamura, HC Amstutz. “Metal ion levels and component wear after revision of metal-on-metal hip resurfacing to total hip replacement: A Report of Three Cases.” The Annual Meeting of the Orthopaedic Research Society poster #1194. Long Beach, CA. January 13-16, 2011.

KM Takamura, E Ebramzadeh, HC Amstutz. “Ion results from Conserve Plus metal-on-metal hip resurfacings and relationship with component orientation.” The Annual Meeting of the Orthopaedic Research Society poster #1205. Long Beach, CA. January 13-16, 2011.

HC Amstutz, KM Takamura, PA Campbell, Z Lu, E Ebramzadeh. “In vivo wear analysis of 29 Conserve Plus® metal-on-metal hip resurfacings and relationship with ‘adverse local tissue reaction’.” The Annual Meeting of the Orthopaedic Research Society poster #1201. Long Beach, CA. January 13-16, 2011

HC Amstutz, KM Takamura, M Le Duff. “Metal-on-metal hip resurfacing in ideal candidates- 3 to 13 year follow-up.” American Academy of Orthopaedic Surgeons Annual Meeting. San Diego, CA February 14-19, 2011. Podium presentation no. 045.

E Ebramzadeh, PA Campbell, Z Lu, KM Takamura, HC Amstutz, K De Smet. “Failure cases and modes of modern metal-on-metal hip resurfacing implants.” American Academy of Orthopaedic Surgeons Annual Meeting, San Diego, CA. February 14-19, 2011. Podium presentation no. 035.

KM Takamura, R Sidaginamale, J Gandhi, A Nargol, D Langton. “Metal ion levels after revision of large head metal-on-metal hip replacements with abnormal wear” American Academy of Orthopaedic Surgeons Annual Meeting. San Francisco, CA February 9, 2012. Podium presentation no. 557.

KM Takamura, A Nargol, A Taylor, D Langton. “Metal ion analysis in patients with metal-on-metal hip replacements: whole blood vs. serum” American Academy of Orthopaedic Surgeons Annual Meeting. San Francisco, CA February 8, 2012. Podium presentation no. 309.

D Langton, T Joyce, J Gandhi, R Sidaginamale, J Lord, KM Takamura, A Nargol. “The main issue of large diameter MoM total hip arthroplasty: the taper junction” American Academy of Orthopaedic Surgeons Annual Meeting. San Franciso, CA February 9, 2012. Podium presentation no. 562.

D Langton, J Gandhi, R Sidaginamale, KM Takamura, A Nargol. “The clinical implications of an elevated blood metal ion result post MoM hip resurfacing” American Academy of Orthopaedic Surgeons Annual Meeting. San Francisco, CA February 9, 2012. Podium presentation no. 569.

KM Takamura, R Sidaginamale, J Gandhi, A Nargol, D Langton. “Metal ion levels after revision of large head metal-on-metal hip replacements with abnormal wear” Orthopedic Research Society Annual Meeting. San Francisco, CA February 4, 2012. Podium Presentation no. 0082

KM Takamura, A Nargol, A Taylor, D Langton. “Metal ion analysis in patients with metal-on-metal hip replacements: whole blood vs. serum” Orthopedic Research Society Annual Meeting. San Francisco, CA February 4, 2012. Podium presentation no. 0084

KM Takamura, D Nawabi, N Nassif, M Elpers, K Stoner, T Wright, D Padgett. “Using contact-patch-to-rim distance to predict edge loading in metal-on-metal hip resurfacing retrievals.” Orthopedic Research Society. San Antonio, TX. January 26-29, 2013. Poster no. 1786

KM Takamura, T Nath, P Maher, EP Su. “Survivorship of standard vs. modified posterior surgical approaches in metal-on-metal hip resurfacing arthroplasty.” Orthopedic Research Society. San Antonio, TX. January 26-29, 2013. Poster no. 1003.

BM Cash, E Lord, SD Zoller, KM Takamura, D Jeffcoat, EE Johnson. “Operative versus nonoperative treatment of humeral shaft fractures.” Orthopaedic Trauma Association 34th Annual Meeting. Orlando, FL. October 18-20, 2018. Paper no. 128.

KM Takamura, S Ahmad, A Scaduto, RE Bowen. “Referral patterns to a pediatric scoliosis clinic based on Cobb angles measured by community radiologists: implications for treatment.” American Academy of Pediatrics (AAP) National Conference and Exhibition. Orlando, FL. November 3, 2018. Podium presentation.

KM Takamura, N Ho, C McCarty, J Diehl, E Ebramzadeh, S Sangiorgio. “Risk of Periprosthetic Fracture in THA Following 1-29 Years of In-Vivo Service and Bone Remodeling: A Postmortem Biomechanical Investigation.” Orthopaedic Research Society Annual Meeting Austin, TX. February 4, 2019. Podium Presentation no. 282)