Research and Clinical Trials
UCLA conducts research for a wide range of medical disorders and
offers patients opportunities to participate in research and
Visit our Office of Clinical Trials website for
more information about clinical trials.
Below are some featured trials at UCLA. Click here
for a PDF of these trials. You may also visit the links to
the right for additional trials from our clinical departments.
UCLA Aftercare Research Program
The Aftercare Research Program at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA will provide free treatment and assessment for participants in a clinical research study that is designed to improve the understanding of psychotic disorders and to develop more effective treatments. An initial diagnostic interview will determine a patient’s eligibility. The study will include individual case management, group therapy and the antipsychotic medication risperidone. Family members of patients will be invited to join family psychoeducational meetings. An initial period on risperidone is a requirement of this study, so a change of medication may be needed.
Info: (310) 206-3142 or email firstname.lastname@example.org, email@example.com or www.semel.ucla.edu/aftercare
Attention Deficit Hyperactive Disorder
UCLA researchers seeking children between the ages of 8 and 12 to test a new treatment for attention deficit hyperactivity disorder (ADHD) that does not use medication. Participants should not be taking medication for ADHD but must display symptoms of inattentiveness, hyperactivity and/or impulsive behavior. The treatment involves stimulating a sensory nerve in the skin of the forehead with mild electrical signals during sleep. The trigeminal nerve sends signals from the forehead into many parts of the brain. Participants will wear an electrically conductive patch, which resembles a band aid on the forehead. The electrical charge is so small that the device is powered by a nine-volt battery. The power pack, roughly the size of a mobile phone, will be clipped to the child’s pajamas. Participants will come to UCLA ADHD clinic for a total of five visits over the course of six weeks. Treatment will be given every night at home for four weeks. In addition to standard behavioral measures for ADHD symptoms, participants will be assessed at the beginning and end of the study with EEG, which measures changes in brain wave activity. Participants will be randomly assigned to one group who will receive trigeminal nerve stimulation (TNS) or another group, who will receive a placebo patch. At the end of the study, participants will be given the option to receive four weeks of actual TNS. All evaluations, assessments, equipment, supplies and parking at UCLA will be provided at no cost to participating families. Families may receive up to $175 for participation.
Info: (310) 267-4798 or firstname.lastname@example.org or www.semel.ucla.edu/adhdandmood
Family-focused Treatment for Childhood OCD
Does your child have Obsessive Compulsive Disorder (OCD)? Does he/she have recurring thoughts that make no sense, but makes him/ her feel bad; wash excessively or have fear of touching “contaminated” things; check and double-check more than necessary and have to do things over and over again? A UCLA research study is looking for kids and teens between 8 and 17 years of age with OCD to study family involvement in non-medication cognitive behavioral therapy (CBT). Eligible participants will receive 14 weeks of free treatment.
Info: (310) 206-1350
Child Anxiety Study
This UCLA research study conducted by Susanna Chang, PhD, is looking for children ages 8 to 17 with social anxiety, generalized anxiety and separation anxiety to participate along with their parents in an investigation of the usefulness of a novel computer-based attention training treatment for childhood anxiety. Participation involves EEG recordings and eight weeks of a non-medication attention-training treatment for children. Parents of eligible study youth are also asked to participate in similar attention-training treatment to study how their participation may improve their child’s anxiety.
Info: (310) 825-2064
Child Obsessive Compulsive Disorder Study
This UCLA research study conducted by Susanna Chang, PhD, is looking for children ages 8 to 17 to participate in a study to investigate the usefulness of a novel computer-based attention-training treatment for childhood OCD. Participation involves EEG recordings and four weeks of a non-medication attention-training treatment.
Info: (310) 825-2064
Cognitive Physiological Correlates of Anxiety in Youth
This study, conducted by Michelle Rozenman, PhD, and John Piacentini, PhD, at the UCLA Semel Institute for Neuroscience and Human Behavior, is looking for healthy children between the ages of 9 and 17 years, who are living with their parents or legal guardian, for a psychological evaluation about how youths perceive and think about the world. Participants will undergo two computer tasks and two problem solving tasks and have their heart rate and breathing monitored. The study takes approximately three hours and requires one visit to UCLA. Please note that the study does not provide transportation to/from or parking at UCLA.
Info: (310) 794-2215
Child Attention & Real-world Emotion Study
Does your child have frequent worries or fears? UCLA is recruiting children between the ages of 6 and 9 for a study about how attention may be related to the ability to manage emotions like anxiety or fear. The research study involves questionnaires and interviews about you and your child’s mood and behaviors, computer tasks to see how kids process emotional information (like facial expressions), and recording of your child’s brain waves while they view emotional information. The study involves two weekends of short (five to 10 minute) phone interviews about your child’s activities and emotions, as well as short (45 second) audio recordings of your child’s emotional expressions. The study involves two visits to our research laboratory (for three hours total) and two weekends of phone calls. We will also ask parents to complete a few questionnaires at six and 12 months following the last laboratory visit. Participants will receive compensation for their time and transportation costs. Interested families may be provided with clinical referrals. There are no medical risks associated with this study.
Info: (310) 835-2701
For those who are suffering from feelings of depression, sadness, hopelessness, memory loss, concentration difficulties, lack of energy, or loss of interest and pleasure in activities UCLA is conducting a 12-month research study using an experimental combination of two drugs and a placebo (an inactive substance). If you are 60 years of age or older, not currently receiving any psychiatric treatment with effective medications, you may qualify. Medical and psychiatric evaluations and limited physical exams are provided as a part of the study. Participants will undergo a PET scan and an MRI scan. Evaluations and study drug are provided at no charge.
Info: (310) 983-3375 or (310) 794-4619
UCLA is conducting a 12-month research study for those who are suffering from depression, sadness, hopelessness, memory loss, concentration difficulties, lack of energy, or loss of interest and pleasure in activities, to compare the effects of levomilnacipran (FETZIMA) to placebo for treating geriatric depression. If you are 60 years of age or older, you may qualify. A complete psychiatric evaluation, physical exam and one MRI scan are provided as a part of the study. All participants will be given either levomilnacipran (FETZIMA) or a placebo (an inactive substance). Participants will be compensated up to $200 and parking will be reimbursed.
Info: (310) 794-9523
Tai-Chi for Depression
For those who are suffering from depressive symptoms, lack of energy, and on stable medications for depression, UCLA is conducting a six-month research study involving 12 weekly 60-minute sessions of either a health and education wellness class or a Tai-Chi class. Participants will undergo two functional magnetic resonance imaging (fMRI) scans. A complete psychiatric evaluation will be provided. If you are 60 years of age or older, you may qualify. Participants will be compensated.
Info: (310) 794-9523
Positive and Negative Emotion Study
We are currently investigating the neurobiological basis for positive and negative emotions. If you are found to be eligible after completing a 5-10 minute online screening questionnaire, you may earn up to $250 for participating. Additionally, some individuals will be randomly invited to come back 3 months later and earn an additional $125. The study involves coming in for two visits (3-4 hours each) within a one week period and completing a 20-30 minute online questionnaire 3 months later. Over the course of both visits you will complete a clinical interview, questionnaires, computer tasks, and a one hour MRI brain scan. At certain points we will also connect you to devices that measure sweat response, heart rate, muscle tension, and respiration. You will also be asked to provide a blood sample. You may be eligible to participate if you are 18-55 years old and fluent in English.
Info: 310-206-9191 or email@example.com
Irritable Bowel Syndrome
Do you suffer from chronic abdominal pain, discomfort and bloating? Do you experience diarrhea or constipation or both? You may have irritable bowel syndrome (IBS). If so, you may qualify for an investigational research study for a natural, herbal remedy for IBS symptoms. To qualify, you must be a female, between the ages of 18-65 and suffer from IBS. Qualified participants will receive the herbal product medication or placebo, study related testing and physical exams at no cost. Compensation may be provided for time and travel and insurance is not needed.
Info: (877) 906-7797 or www.myclinicaltrial.com/
Memory Enhancement Training or Yoga for Older Adults
For those who are suffering from memory loss, concentration difficulties, or lack of energy, UCLA is conducting a six-month research study comparing a 60-minute weekly memory enhancement training course to yoga meditation. If you are 55 years of age or older and not currently receiving any psychiatric treatment, you may qualify. Medical and psychiatric evaluations and limited physical exams are provided as a part of the study. Participants will undergo two functional magnetic resonance imaging (fMRI) scans. A complete psychiatric evaluation will be provided. Participants will be compensated.
Info: (310) 794-9523 or (310) 794-4619
Memory and Exercise Training (MET) Study
This project is designed to study the relationship of simultaneous exercise and memory training. Volunteers 60 to 75 years of age, in good health and living independently are encouraged to participate. The study will involve memory training, memory testing and physical exercise over the course of 14 weeks. Subjects will be compensated for participation and receive clinically relevant results of assessments.
Info: (310) 825-0545
Menstrual Irregularities and PCOS Study
UCLA researchers are seeking women with and without Polycystic Ovary Syndrome (PCOS). To be eligible, women must be Caucasian and non-Hispanic, between the ages of 18 and 35, have body mass index (BMI) between 18.5 and 25, and have not used hormones (i.e., birth control pills or a Mirena IUD) for the past three months. Participants will receive extensive free medical testing including blood hormone measurements, diabetes screening, ovarian and fat assessment. A small amount of fat will be removed from the abdomen and blood will be drawn for research purposes. Only women with PCOS will take an oral pill that contains either the drug Flutamide or a placebo (sugar pill) for six complete 28-day cycles. The free medical testing will be repeated at the end of the study. Women without PCOS may earn up to $300 and women with PCOS may earn up to $840.
Info: (310) 825-0580; or firstname.lastname@example.org
Obstructive Sleep Apnea (OSA) Research Study
UCLA researchers are seeking patients between the ages of 21 to 75 who have recently been diagnosed with obstructive sleep apnea and have not yet started treatment to participate in a study to see how changes in brain function and structure relate to autonomic impairments. The study is also seeking healthy control participants who are in good health, and non-smokers without sleep disorders. People interested in participating will go through a screening process and those determined eligible will be enrolled in the study. Enrolled participants will be invited to do one or more of the following: MRI scanning; physiological testing; simple, daily home physiological testing, and brief questionnaires using a smart phone. Study participants will not be charged for any study procedure and will be compensated for participation.
Info: (323) 362-8818 email@example.com
Pomegranate Juice Study
The UCLA Longevity Center is studying the effect of pomegranate juice on memory. Volunteers between the ages of 50 and 75 are needed. The study lasts one year and includes five visits to UCLA and $300 compensation for participation.
Info: (310) 825-0545
Post Thrombotic Syndrome Study
Have you been previously diagnosed with a blood clot in your leg or have received prior treatment but still have leg swelling, pain or discomfort? If so, you may be eligible to participate in the ACCESS PTS study -- which aims to evaluate the success of an advanced minimally-invasive technique in treating ‘old’ blood clots and related conditions. The treatment provided in the study includes the use of the EkoSonic® Endovascular System — an FDA cleared device that delivers clot-busting drugs. This treatment will be provided during an overnight stay in the hospital. You will return to the doctor for 4 more outpatient visits in 12 months to monitor the effectiveness of the treatment. Talk to your doctor today if you are interested in participating in this study.
Info: (310) 794-8995 or firstname.lastname@example.org
UCLA researchers are seeking women ages 18 to 55 to help understand brain activity changes associated with a chronic pain condition called vulvodynia. Women who have been diagnosed with vulvodynia or vestibulodynia, or those with chronic pain around the opening of the vagina, may be eligible to participate. Participation includes a pelvic exam, sensitivity testing and MRI scans. Volunteers can earn up to $130 for participating.
Info: (310) 825-5255 or email@example.com
Effects of E-cigarettes on Sympathetic Nerve Activity
Seeking healthy men and women between the ages of 21-45 for a research study on the effect of E-cigarettes on sympathetic nerve activity (nerves that carry adrenaline) and blood levels of anti-oxidants . Must be a NON-SMOKER or you must be an E-cigarette user. The study will involve either a two-hour visit, or three two-hour visits (depending on which group you're in) to the UCLA Clinical and Translational Research Center. Monetary compensation provided.
Contact Kacey Peters at (310) 825-3510 or firstname.lastname@example.org to learn more about the study.
Effects of E-Cigarettes and Traditional Cigarettes on Arterial Inflammation
UCLA research study seeks healthy adults between the ages of 21-45 to test the effects of electronic (E)-cigarettes on blood vessel function and blood levels of anti-oxidants (protective compounds). Current tobacco cigarette smokers or current e-cigarette users may be eligible. No dual users. The study involves one visit, approximately 3.5 hours. Participants will undergo blood tests and a scan to measure blood vessel inflammation. Compensation is $100 at the completion of the study.
Contact Kacey Peters at (310) 825-3510 or email@example.com to learn more about the study.
For more information about Clinical Trials offered to
cancer patients, visit:
or call UCLA Jonsson Comprehensive Cancer Center (JCCC) Clinical
Trials Hotline at (888) 798-0719.