Education

Fellowship
UCLA School of Medicine, 2011
Fellowship
UCLA School of Medicine, 2010
Fellowship
University of Alberta Hospital, 2008
Residency
University of Alberta Hospital, 2005
MD
University of Alberta Faculty of Medicine, 2002

Medical Board Certifications

Internal Medicine
American Board of Internal Medicine, 2013

Gender

Male

State License

A108268
  • About Me

    About Me

    ACADEMIC/PROFESSIONAL TITLE
    • Associate Director, Mechanical Circulatory Support Device Services

    Links

  • Education

    Medical Board Certifications

    Internal Medicine
    American Board of Internal Medicine, 2013

    Education

    Fellowship
    UCLA School of Medicine, 2011
    Fellowship
    UCLA School of Medicine, 2010
    Fellowship
    University of Alberta Hospital, 2008
    Residency
    University of Alberta Hospital, 2005
    MD
    University of Alberta Faculty of Medicine, 2002
  • Clinical Interests
    • Angina
    • Atherosclerosis
    • Atrial Fibrillation
    • Cardiac Biopsy
    • Cardiac Catheterization
    • Cardiomyopathy
    • Cholesterol
    • Congestive Heart Failure
    • Coronary Artery Disease
    • General Cardiology
    • Heart Transplant
    • Heart Transplant After Surgery
    • Heart Valve Disease
    • Hypertension
    • Ischemia (Heart)
    • Transthoracic Echocardiography
  • Research

    Research Interest

    Cardiovascular Regenerative Therapies, Ventricular Assist Devices, Clinical Stem Cell Trials, Tissue Engineering. See more »

    Publications

    • Nsair A, Archer S, London B, Hashimoto K, Michelakis E “Selective Loss of Hypoxic Pulmonary Vasoconstriction in Swap Kv 1.1-1.5 Mice.” Am. J. Resp. Crit. Care Med. 2001 July,1-235.
    • Archer SL, Wu XC, Thebaud B, Nsair A, Bonnet S, Tyrrell B, McMurtry MS, Hashimoto K, Harry G, Michelakis ED “Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.” Circ. Res. 2004 Aug 6; 95(3): 308-18.
    • Michelakis ED, Rebeyka I, Wu X, Nsair A, Thebaud B, Hashimoto K, Dyck JR, Harmony A, Harry G, Barr A, Archer SL “O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor.” Circ. Res. 2002 Sep; 91(6):478-86.
    • Michelakis ED, Hampl V, Nsair A, Wu X, Harry G, Haromy A, Gurtu R, Archer SL. “Diversity in mitochondrial function explains differences in vascular oxygen sensing.” Circ. Res. 2002 Jun; 90(12):1307-15.
    • Archer SL, London B, Hampl V, Wu X, Nsair A, Puttagunta L, Hashimoto K, Waite RE, Michelakis ED. “Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage-gated potassium channel Kv 1.5.” FASEB J. 2001 Aug; 15(10):1801-3.
    • Michelakis ED, Weir EK, Wu X, Nsair A, Waite R, Hashimoto K, Puttagunta L, Knaus HG, Archer SL. “Potassium channels regulate tone in rat pulmonary veins.” Am J Physiol Lung Cell Mol Physiol. 2001 June; 280(6):L1138-47.
    • Schenke-Layland K, Stock UA, Nsair A, Xie J, Angelis E, Fonseca CG, Larbig R, Mahajan A, Shivkumar K, Fishbein MC, Maclellan WR. “Cardiomyopathy is associated with structuralremodeling of heart valve extracellular matrix.” Eur. Heart J. 2009 Sep;30(18):2254-65
    • Nsair A, Schenke-Layland K. Invited commentary. Ann. Thoracic Surg. 2009 Aug;88(2):513-4.
    • Schenke-Layland K, Nsair A, Van Handel B, Angelis E, Gluck JM, Votteler M, Goldhaber JI, Mikkola HK, Kahn M, Maclellan WR. “Recapitulation of the embryonic cardiovascular progenitor cell niche.” Biomaterials. 2011 Apr;32(11):2748-56.
    • Nsair A, W.R. MacLellan “Induced Pluripotent Stem Cells for Regenerative Cardiovascular Therapies and Biomedical Discovery.” Adv. Drug Deliv. Rev. 2011 Apr 30;63(4-5):324-30.
    • Nsair A, Schenke-Layland K, Van Handel B, H. Mikkola, W.R. MacLellan “Characterization and Therapeutic Potential of Induced Pluripotent Stem Cell-Derived Cardiovascular Progenitor Cells.” PLoS ONE, Oct. 2012.
    • Votteler M, Carvajal Berrio DA, Horke A, Sabatier L, Reinhardt DP, Nsair A, Aikawa E, Schenke-Layland K. “Elastogenesis at the onset of human cardiac valve development.”Development. 2013 May 1. PMID: 23637335.
    • Yagishita D, Ajijola OA, Vaseghi M, Nsair A, Zhou W, Yamakawa K, Tung R, Mahajan A, Shivkumar K. “Electrical homogenization of ventricular scar by application of collagenase: a novel strategy for arrhythmia therapy.” Circ Arrhythm Electrophysiol. 2013 Aug 1;6(4):776-83. doi: 10.1161/CIRCEP.113.000448.
    • Cheng RK, Depasquale EC, Deng MC, Nsair A, Horwich TB. “Obesity in heart failure: impact on survival and treatment modalities.” Expert Rev Cardiovasc Ther. 2013 Aug 14.
    • Sasikanth Adigopula, MD, Rey P. Vivo, MD, Eugene C. DePasquale, MD, Ali Nsair, MD, Mario C. Deng, MD, FESC “Management of ACCF/AHA Stage C Heart Failure.” Cardiol Clin. 2014 Feb;32(1):73-93.
    • Nsair A, Liem DA, Cadeiras M, Cheng RK, Allareddy M, Kwon M, Shemin R, Deng MC. “Molecular basis of recovering on mechanical circulatory support.” Heart Fail Clin. 2014 Jan;10(1 Suppl):S57-62.
    • Ling Wu, Carolina Bluguermann, Levon Kyupelyan, Brooke Latour, Stephanie Gonzalez, Saumya Shah, Zoran Galic, Sundi Ge, Yuhua Zhu, Frank A. Petrigliano, Ali Nsair, Santiago G. Miriuka, Xinmin Li, Karen M. Lyons, Gay M. Crooks, David R. McAllister, Ben Van Handel, John S. Adams, and Denis Evseenko “Human Developmental Chondrogenesis as a Basis for Engineering Chondrocytes from Pluripotent Stem Cells.” Stem Cell Reports, Dec 12, 2013.
  • News & Awards

    In the News

    Awards