Education

Residency
Urology, UCLA School of Medicine, 2009
Internship
Surgery, UCLA School of Medicine, 2004
Degree
MD, UCLA School of Medicine, 2003
Degree
PhD, UCLA, 2002

Medical Board Certifications

Urology
American Board of Urology, 2011

Gender

Male

State License

A89934
  • About Me

    About Me

    Preferred Name: Arnold I. Chin

    Education/Certification

    • PhD, UCLA, 2002

    Professional Memberships

    • American Urological Association
    • American Association of Cancer Research
    • Society of Urology Oncology

    Academic & Medical Staff Appointments

    • Assistant Professor Department of Urology, UCLA School of Medicine 2009
    • Broad Stem Cell Research Center 2009
    • Tumor Immunology Program Area of the Jonsson Comprehensive Cancer Center 2009
    • Genitourinary Oncology Program Area of the Jonsson Comprehensive Cancer Center 2009

    Patient Education (PDFs)

    Links

  • Locations

    Frank Clark Urological Center

    (primary location)
    Address
    200 UCLA Medical Plaza
    Suite 140
    Los Angeles, California 90095
    Phone
    310-794-7700
  • Education

    Medical Board Certifications

    Urology
    American Board of Urology, 2011

    Education

    Residency
    Urology, UCLA School of Medicine, 2009
    Internship
    Surgery, UCLA School of Medicine, 2004
    Degree
    MD, UCLA School of Medicine, 2003
    Degree
    PhD, UCLA, 2002
  • Clinical Interests
    • Bladder Cancer
    • Hematuria
    • Prostatitis
    • Robotic Surgery-Bladder
    • Urinary Tract Infection (Male)
  • Research

    Research Interest

    My clinical expertise includes urologic oncology and renal transplantation, performing open, laparoscopic, and robotic-assisted surgeries for bladder, kidney, and prostate cancer patients.

    Our laboratory studies the tumor microenvironment in prostate and bladder cancer using a combination of animal models, human reconstitution systems, and primary tumor and hematopoietic cells. We are interested in several aspects including the following:

    1. Molecular mechanisms in programing tumor-infiltrating lymphocytes. The nature and composition of immune cells in cancer have been linked with tumor grade and overall survival. However, the determinants that lead to immune infiltrating cells in cancer is unclear. We are studying the endogenous signals, innate immune, and adaptive immune pathways that program the composition of the tumor immune microenvironment, and how these will influence tumor proliferation, invasion, and metastasis. We are also interested in how we can reprogram the immune components of the tumor microenvironment to shape tumorigenicity.

    2. Mechanisms controlling development and differentiation of cancer stem cells. Cancer initiating cells share similar features to stem cells with their ability for self-renewal and pluripotency. These cell populations may explain the recurrent nature and drug resistance of cancer. We are studying the cell intrinsic signals as well as the cell extrinsic influences from immune and stromal cells of the cancer stem cell in their differentiation, ability to undergo epithelial-to-mesenchymal transition, and development of an invasive phenotype.

    Our studies will provide fundamental understanding of the tumor microenvironment, as well as develop therapeutic targets, novel immune-based platforms, and stem cell based therapies against cancer.

    Publications

  • News & Awards

    In the News

    Awards

    • STOP Cancer Research Career Development Award 2010
    • American Association of Cancer Research Career Development Award for Translational Cancer Research 2010
  • Videos