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Alex-Bui Photo

Alex Bui, PhD

Director, Medical & Imaging Informatics (MII) Group
Director, Medical Informatics Home Area | Graduate Program in Biosciences
Professor, Departments of Radiological Sciences, Bioengineering & Bioinformatics
Specialty
Medical Imaging Informatics

Contact Information (310) 794-3539 or (310) 794-8954 x43540
[email protected]

Mailing Address:
UCLA Radiological Sciences
BOX 956916, 924 Westwood Blvd, Ste 420
Los Angeles, CA 90095

Work Address:
Laboratory
Bank of America Building
Los Angeles, CA 90095

Dr. Bui is a Professor of Radiological Sciences, Bioengineering, and Bioinformatics; and Director of the UCLA Medical & Imaging Informatics (MII) group. He holds the David Geffen Chair in Informatics. His primary research interests include distributed health information systems, including mHealth; methods using observational data sources (e.g., the electronic health record, EHR), including translational applications and evaluation of AI-based methods for healthcare (e.g., machine and reinforcement learning); and data visualization. He has extensive experience in leading NIH grants from across multiple different institutes (NIBIB, NCI, NLM, NINDS, NIMHD) in areas related to biomedical informatics. He is currently a Senior Associate Director for UCLA’s Clinical and Translational Science Institute (CTSI), overseeing informatics services and training; Associate Director for Medical Informatics in the Institute for Precision Health (IPH); Co-Director of the Center for SMART Health; and Director for UCLA’s Medical Informatics Home Area program. 

Publications

2021
Friedman J, Syvertsen JL, Bourgois P, Bui AAT, Beletsky L, Pollini R. Intersectional structural vulnerability to abusive policing among people who inject drugs: A mixed methods assessment in California's central valley. Int J Drug Policy. 2021 Jan;87:102981. doi: 10.1016/j.drugpo.2020.102981. Epub 2020 Oct 28. PMID: 33129133; PMCID: PMC7940555.

Myint A, Corona E, Yang L, Nguyen BS, Lin C, Huang MZ, Shao P, Mwengela D, Didero M, Asokan I, Bui AAT, Hsu W, Maehara C, Naini BV, Kang Y, Bastani R, May FP. Gastroenterology visitation and reminders predict surveillance uptake for patients with adenomas with high-risk features. Sci Rep. 2021 Apr 22;11(1):8764. doi: 10.1038/s41598-021-88376-4. PMID: 33888839; PMCID: PMC8062682.

Ross MK, Eckel SP, Bui AAT, Gilliland FD. Asthma clustering methods: a literature-informed application to the children's health study data. J Asthma. 2021 May 18:1-14. doi: 10.1080/02770903.2021.1923738. Epub ahead of print. PMID: 33926348. Friedman J, Mann NC, Hansen H, Bourgois P, Braslow J, Bui AAT, Beletsky L, Schriger DL. Racial/Ethnic, Social, and Geographic Trends in Overdose-Associated Cardiac Arrests Observed by US Emergency Medical Services During the COVID-19 Pandemic. JAMA Psychiatry. 2021 May 26. doi: 10.1001/jamapsychiatry.2021.0967. Epub ahead of print. PMID: 34037672.

2020
Barnholtz-Sloan JS, Rollison DE, Basu A, Borowsky AD, Bui AAT, DiGiovanna J, Garcia-Closas M, Genkinger JM, Gerke T, Induni M, Lacey JV Jr, Mirel L, Permuth JB, Saltz J, Shenkman EA, Ulrich CM, Zheng WJ, Nadaf S, Kibbe WA. Cancer Informatics for Cancer Centers (CI4CC): Building a Community Focused on Sharing Ideas and Best Practices to Improve Cancer Care and Patient Outcomes. JCO Clin Cancer Inform. 2020 Feb;4:108-116. doi: 10.1200/CCI.19.00166. PMID: 32078367; PMCID: PMC7186581.

Bui AAT, Hosseini A, Rocchio R, Jacobs N, Ross MK, Okelo S, Lurmann F, Eckel S, Dzubur E, Dunton G, Gilliland F, Sarrafzadeh M, Habre R. Biomedical REAl-Time Health Evaluation (BREATHE): toward an mHealth informatics platform. JAMIA Open. 2020 May 7;3(2):190-200. doi: 10.1093/jamiaopen/ooaa011. PMID: 32734159; PMCID: PMC7382637.

Zhang T, Chen M, Bui AAT. Diagnostic Prediction with Sequence-of-sets Representation Learning for Clinical Events. Artif Intell Med Conf Artif Intell Med (2005-). 2020 Aug;12299:348-358. doi: 10.1007/978-3-030-59137-3_31. Epub 2020 Sep 26. PMID: 34036298; PMCID: PMC8143801.

Garon, E, Cummings A*, Gukasyan J, Lu H, Grogan T, Sunga G, Fares C, Hornstein N, Zaretsky J, Carroll J, Bachrach B, Akingbemi W, Li D, Noor Z, Lisberg A, Goldman J, Elashoff D, Bui AAT, Ribas A, Dubinett S, Rossetti M. Mutational landscape influences immunotherapy outcomes among non-small cell lung cancer patients with human leukocyte antigen supertype B44. Nature Cancer, 1. 1167–1175 (2020). doi:10.1038/s43018-020-00140-1.

2019
Gaonkar B, Beckett J, Villaroman D, Ahn C, Edwards M, Moran S, Attiah M, Babayan D, Ames C, Villablanca JP, Salamon N, Bui AAT, Macyszyn L. Quantitative Analysis of Neural Foramina in the Lumbar Spine: An Imaging Informatics and Machine Learning Study. Radiol Artif Intell. 2019 Mar 6;1(2):180037. doi: 10.1148/ryai.2019180037. PMID: 33937788; PMCID: PMC8017393.

Li K, Habre R, Deng H, Urman R, Morrison J, Gilliland FD, Ambite JL, Stripelis D, Chiang YY, Lin Y, Bui AAT, King C, Hosseini A, Vliet EV, Sarrafzadeh M, Eckel SP. Applying Multivariate Segmentation Methods to Human Activity Recognition From Wearable Sensors' Data. JMIR Mhealth Uhealth. 2019 Feb 7;7(2):e11201. doi: 10.2196/11201. PMID: 30730297; PMCID: PMC6386646.

Shen S, Han SX, Aberle DR, Bui AAT, Hsu W. An Interpretable Deep Hierarchical Semantic Convolutional Neural Network for Lung Nodule Malignancy Classification. Expert Syst Appl. 2019 Aug 15;128:84-95. doi: 10.1016/j.eswa.2019.01.048. Epub 2019 Jan 18. PMID: 31296975; PMCID: PMC6623975.

Hosseini A, Zamanzadeh D, Valencia L, Habre R, Bui AAT, Sarrafzadeh M. Domain Adaptation in Children Activity Recognition. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul;2019:1725-1728. doi: 10.1109/EMBC.2019.8857135. PMID: 31946230.

Goodman-Meza D, Weiss RE, Gamboa S, Gallegos A, Bui AAT, Goetz MB, Shoptaw S, Landovitz RJ. Long term surgical outcomes for infective endocarditis in people who inject drugs: a systematic review and meta-analysis. BMC Infect Dis. 2019 Nov 8;19(1):918. doi: 10.1186/s12879-019-4558-2. PMID: 31699053; PMCID: PMC6839097.

Petousis P, Winter A, Speier W, Aberle DR, Hsu W, Bui AAT. Using Sequential Decision Making to Improve Lung Cancer Screening Performance. IEEE Access. 2019;7:119403-119419. doi: 10.1109/ACCESS.2019.2935763. Epub 2019 Aug 16. PMID: 32754420; PMCID: PMC7402617.

Norris KC, Duru OK, Alicic RZ, Daratha KB, Nicholas SB, McPherson SM, Bell DS, Shen JI, Jones CR, Moin T, Waterman AD, Neumiller JJ, Vargas RB, Bui AAT, Mangione CM, Tuttle KR; CURE-CKD investigators. Rationale and design of a multicenter Chronic Kidney Disease (CKD) and at-risk for CKD electronic health records-based registry: CURE-CKD. BMC Nephrol. 2019 Nov 20;20(1):416. doi: 10.1186/s12882-019-1558-9. PMID: 31747918; PMCID: PMC6868861.

Van Horn J, Abe S, Ambite JL, Atwood TK, Beard N, Bellis L, Bhattrai A, Bui AAT, Burns G, Fierro L, Gordon J, Grethe J, Kamdar J, Lei X, Leman K, McGrath A, Mulder N, O’Driscoll C, Stewart C, Tyagi S. Advancing the international da-ta science workforce through shared training and education. F1000 Research, Open Science, 2019. doi: 10.12688/f1000research.18357.1.

2018
Luo Y, Abiri P, Zhang S, Chang CC, Kaboodrangi AH, Li R, Sahib AK, Bui AAT, Kumar R, Woo M, Li Z, Packard RRS, Tai YC, Hsiai TK. Non-Invasive Electrical Impedance Tomography for Multi-Scale Detection of Liver Fat Content. Theranostics. 2018 Feb 8;8(6):1636-1647. doi: 10.7150/thno.22233. PMID: 29556346; PMCID: PMC5858172.

Petousis P, Han SX, Hsu W, Bui AAT. Generating Reward Functions Using IRL Towards Individualized Cancer Screening. Artif Intell Health (2018). 2019;11326:213-227. doi: 10.1007/978-3-030-12738-1_16. Epub 2019 Feb 21. PMID: 31363717; PMCID: PMC6667225.

Hosseini A, Fazeli S, Vliet EV, Valencia L, Habre R, Sarrafzadeh M, Bui AAT. Children Activity Recognition: Challenges and Strategies. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:4331-4334. doi: 10.1109/EMBC.2018.8513320. PMID: 30441312; PMCID: PMC7339805.

Caufield JH, Liem DA, Garlid AO, Zhou Y, Watson K, Bui AAT, Wang W, Ping P. A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts. J Vis Exp. 2018 Sep 20;(139):58392. doi: 10.3791/58392. PMID: 30295669; PMCID: PMC6235242.

Bakir M, Jackson NJ, Han SX, Bui AAT, Chang E, Liem DA, Ardehali A, Ardehali R, Baas AS, Press MC, Cruz D, Deng MC, DePasquale EC, Fonarow GC, Khuu T, Kwon MH, Kubak BM, Nsair A, Phung JL, Reed EF, Schaenman JM, Shemin RJ, Zhang QJ, Tseng CH, Cadeiras M. Clinical phenomapping and outcomes after heart transplantation. J Heart Lung Transplant. 2018 Aug;37(8):956-966. doi: 10.1016/j.healun.2018.03.006. Epub 2018 Mar 22. PMID: 29802085; PMCID: PMC6064662.

Caufield JH, Zhou Y, Garlid AO, Setty SP, Liem DA, Cao Q, Lee JM, Murali S, Spendlove S, Wang W, Zhang L, Sun Y, Bui AAT, Hermjakob H, Watson KE, Ping P. A reference set of curated biomedical data and metadata from clinical case reports. Sci Data. 2018 Nov 20;5:180258. doi: 10.1038/sdata.2018.258. PMID: 30457569; PMCID: PMC6244181.

Petousis P, Han SX, Hsu W, Bui AAT. Generating Reward Functions Using IRL Towards Individualized Cancer Screening. Artif Intell Health (2018). 2019;11326:213-227. doi: 10.1007/978-3-030-12738-1_16. Epub 2019 Feb 21. PMID: 31363717; PMCID: PMC6667225.

2017
Shen S, Han SX, Petousis P, Weiss RE, Meng F, Bui AAT, Hsu W. A Bayesian model for estimating multi-state disease progression. Comput Biol Med. 2017 Feb 1;81:111-120. doi: 10.1016/j.compbiomed.2016.12.011. Epub 2016 Dec 22. PMID: 28038345; PMCID: PMC5508542.

Ping P, Watson K, Han J, Bui AAT. Individualized Knowledge Graph: A Viable Informatics Path to Precision Medicine. Circ Res. 2017 Mar 31;120(7):1078-1080. doi: 10.1161/CIRCRESAHA.116.310024. PMID: 28360346; PMCID: PMC6847981.

Jagodnik KM, Koplev S, Jenkins SL, Ohno-Machado L, Paten B, Schurer SC, Dumontier M, Verborgh R, Bui AAT, Ping P, McKenna NJ, Madduri R, Pillai A, Ma'ayan A. Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop. J Biomed Inform. 2017 Jul;71:49-57. doi: 10.1016/j.jbi.2017.05.006. Epub 2017 May 10. PMID: 28501646; PMCID: PMC5545976.

Bui AAT, Van Horn JD; NIH BD2K Centers Consortium. Envisioning the future of 'big data' biomedicine. J Biomed Inform. 2017 May;69:115-117. doi: 10.1016/j.jbi.2017.03.017. Epub 2017 Mar 30. PMID: 28366789; PMCID: PMC5613673.

Hojaiji H, Kalantarian H, Bui AAT, King CE, Sarrafzadeh M. Temperature and Humidity Calibration of a Low-Cost Wireless Dust Sensor for Real-Time Monitoring. 2017 IEEE Sens Appl Symp (SAS) (2017). 2017 Mar;2017:10.1109/SAS.2017.7894056. doi: 10.1109/SAS.2017.7894056. Epub 2017 Apr 12. PMID: 29457803; PMCID: PMC5813487.

Hosseini A, Buonocore CM, Hashemzadeh S, Hojaiji H, Kalantarian H, Sideris C, Bui AAT, King CE, Sarrafzadeh M. Feasibility of a Secure Wireless Sensing Smartwatch Application for the Self-Management of Pediatric Asthma. Sensors (Basel). 2017 Aug 3;17(8):1780. doi: 10.3390/s17081780. PMID: 28771168; PMCID: PMC5580199.

Garcia-Gathright JI, Matiasz NJ, Adame C, Sarma KV, Sauer L, Smedley NF, Spiegel ML, Strunck J, Garon EB, Taira RK, Aberle DR, Bui AAT. Evaluating Casama: Contextualized semantic maps for summarization of lung cancer studies. Comput Biol Med. 2018 Jan 1;92:55-63. doi: 10.1016/j.compbiomed.2017.10.034. Epub 2017 Nov 3. PMID: 29149658; PMCID: PMC5762403.

Ding Y, Abiri A, Abiri P, Li S, Chang CC, Baek KI, Hsu JJ, Sideris E, Li Y, Lee J, Segura T, Nguyen TP, Bui AAT, Sevag Packard RR, Fei P, Hsiai TK. Integrating light-sheet imaging with virtual reality to recapitulate developmental cardiac mechanics. JCI Insight. 2017 Nov 16;2(22):e97180. doi: 10.1172/jci.insight.97180. PMID: 29202458; PMCID: PMC5752380.
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