Faculty Directory

Peng Hu, PhD

Professional Training & Experience

• Professor of Radiology, UCLA, Los Angeles, CA, 2020 - Present
• Associate Professor of Radiology, UCLA, Los Angeles, CA, 2016 - 2020
• Assistant Professor of Radiology, UCLA, Los Angeles, CA, 2010 - 2016
• Instructor in Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 2010
• Post-Doctoral Research Fellow, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 2008 - 2010
• PhD in Biomedical Engineering, University of Virginia, Charlottesville, VA, 2002 - 2008
• M.S. in Biomedical Engineering, Tsinghua University, Beijing, China, 2000 - 2002
• B.S. in Biomedical Engineering, Tsinghua University, Beijing, China, 1995 - 2000

Clinical/Research Interests

Dr. Hu is interested in developing novel magnetic resonance imaging techniques for a variety of clinical imaging applications, including coronary artery MRI, imaging for electrophysiological ablations, pediatric/fetal imaging for congenital heart defects, and cardiovascular imaging in general. He is also interested in MRI for interventional applications. The following are two examples of Dr. Hu’s recent research projects:

1. Cardiovascular MRI for Congenital Heart Disease
   
   Investigators at UCLA developed a cardiovascular magnetic resonance imaging (MRI) technique named 4D MUSIC for pediatric congenital heart disease patients. Compared to the current clinical standard MRI techniques, the MUSIC technique achieves greatly improved definition of cardiovascular anatomy and function and provides high-resolution dynamic coverage of the entire chest using novel MRI pulse sequences and contrast generation mechanisms. The 4D MUSIC technique presents a paradigm shift in cardiovascular MRI for pediatric congenital heart disease and will likely help reduce exposure of these young children to invasive diagnostic catheterization and its associated ionizing radiation.Reference: Han F, Rapacchi S, Khan S, Ayad I, Salusky I, Gabriel S, Plotnik A, Finn JP, Hu P. “Four-Dimensional, Multiphase, Steady-State Imaging with Contrast Enhancement (MUSIC) in the Heart: a Feasibility Study in Children”, Magn Reson Med, 2014, Oct 9. doi: 10.1002/mrm.25491.
2. Myocardial Scar Imaging for Guiding Catheter Ablation of Ventricular Tachycardia 
   
   

   Investigators at UCLA Radiology and UCLA Cardiac Arrhythmia Center have developed a wideband late gadolinium enhancement (LGE) MRI technique for patients with implanted cardiac devices, such as pacemakers and implantable cardioverter defibrillators. The wideband LGE technique eliminates image artifacts associated with conventional LGE technique and enables much improved assessment of myocardial viability and fibrosis for these patients. References: Rashid S, Rapacchi S, Vaseghi M, Tung R, Shivkumar K, Finn JP, Hu P. "Improved late gadolinium enhancement MRI for patients with implanted cardiac devices". Radiology, 2014; 270(1): 269-274 and Stevens S, Tung R, Rashid S, Khan S, Gima J, Cote S, Pavez G, Ennis DB, Finn JP, Boyle N, Shivkumar KS, Hu P. "Device artifact reduction for magnetic resonance imaging of patients with implanted cardioverter defibrillators and ventricular tachycardia: Late gadolinium enhancement correlation with electroanatomical mapping", Heart Rhythm, 2014; 11:289-298

Selected Publications

• Meyer CH, Hu P. "Spiral Parallel Magnetic Resonance Imaging", Conf Proc IEEE Eng Med Biol Soc, 2006;1:369-371
• Wang W, Hu P, Meyer CH. "Estimating spatial resolution of in vivo magnetic resonance images using radiofrequency tagging pulses", Magn Reson Med, 2007;58(1):190-199
• Stoeck CT, Han Y, Peters DC, Hu P, Yeon SB, Kissinger KV, Goddu B, Goepfert L, Manning WJ, Kozerke S, Nezafat R. "Whole heart magnetization-prepared steady-state free precession coronary vein MRI", J Magn Reson Imaging, 2009; 29(6):1293-1299
• Hu P, Chuang ML, Kissinger KV, Goddu B, Goepfert L, Manning WJ, Rofsky NM, Nezafat R. "Non-contrast enhanced pulmonary vein MRI with a spatially selective slab inversion preparation sequence", Magn Reson Med, 2010;63(2):530-536
• Hu P, Chuang ML, Ngo LH, Stoeck CT, Peters DC, Kissinger KV, Goddu B, Goepfert L, Manning WJ, Nezafat R. "Coronary MR imaging: effect of timing and dose of isosorbide dinitrate administration", Radiology, 2010; 254(2):401-409
• Stoeck CT, Hu P, Peters DC, Kissinger KV, Goddu B, Goepfert L, Manning WJ, Kozerke S, Nezafat R. "Optimization of on-resonant magnetization transfer contrast in coronary vein imaging", Magn Reson Med, 2010; 64(6):1849-1854
• Hu P, Stoeck CT, Peters DC, Kissinger KV, Goddu B, Goepfert L, Chan J, Rofsky NM, Manning WJ, Nezafat R. "Non-contrast SSFP pulmonary vein MRA: impact of off-resonance and flow", J Magn Reson Imaging, 2010; 32(5):1255-1261 (Journal Cover Paper)
• Hu P, Chan J, Smink J, Goddu B, Kissinger KV, Goepfert LA, Hauser TH, Rofsky NM, Manning WJ, Nezafat R. "Contrast-enhanced inversion recovery SSFP whole heart coronary MRI bolus infusion of gadobenate dimeglumine at 1.5T", Magn Reson Med, 2011;65(2):392-398
• Akcakaya M, Nam S, Hu P, Tarokh V, Manning WJ, Nezafat R. "Compressed sensing with wavelet domain dependencies for coronary MRI: a retrospective study", IEEE Trans Med Imaging, 2011;30(5):1090-1099
• Akcakaya M, Hu P, Chuang ML, Hauser TH, Ngo LH, Manning WJ, Tarokh V, Nezafat R. "Accelerated non-contrast enhanced pulmonary vein MRA with distributed compressed sensing", J Magn Reson Imaging, 2011;33(5):1248-1255
• Hu P, Hong S, Moghari MH, Goepfert L, Goddu B, Hauser TH, Manning WJ, Nezafat R. "Motion Correction using Coil Arrays (MOCCA) for free-breathing cardiac cine MRI", Magn Reson Med, 2011; 66(2): 467-475. (2011 Philips Cardiovascular MR Science Award Paper)
• Moghari MH, Hu P, Kissinger KV, Goddu B, Goepfert A, Ngo LH, Manning WJ, Nezafat R. "Subject-Specific Estimation of Respiratory Navigator Tracking Factor for Free-Breathing Cardiovascular MR", Magn Reson Med, 2012; 67(6): 1665-1672
• Srinivasan S, Hu P, Kissinger KV, Goddu B, Goepfert L, Schmidt E, Manning WJ, Kozerke S, Nezafat R. "Free-breathing 3D whole heart black blood imaging with motion sensitized driven equilibrium", J Magn Reson Imaging, 2012; 36(2): 379-386
• Rapacchi S, Han F, Natsuaki Y, Kroeker R, Plotnik A, Lehman E, Sayre J, Laub G, Finn JP, Hu P. "High spatial and temporal resolution dynamic contrast-enhanced magnetic resonance angiography (CE-MRA) using compressed sensing with magnitude image subtraction", Magn Reson Med, 2014; 71(5): 1771-1783 (2013 ISMRM Moore Young Investigator Award Semi-Finalist Paper)
• Rashid S, Rapacchi S, Vaseghi M, Tung R, Shivkumar K, Finn JP, Hu P. "Improved late gadolinium enhancement MRI for patients with implanted cardiac devices". Radiology, 2014; 270(1): 269-274
• Stevens S, Tung R, Rashid S, Khan S, Gima J, Cote S, Pavez G, Ennis DB, Finn JP, Boyle N, Shivkumar KS, Hu P. "Device artifact reduction for magnetic resonance imaging of patients with implanted cardioverter defibrillators and ventricular tachycardia: Late gadolinium enhancement correlation with electroanatomical mapping", Heart Rhythm, 2014; 11:289-298
• Song HK, Yan L, Smith RX, Xue Y, Rapacchi S, Srinivasan S, Ennis DB, Hu P, Pouratian N, Wang JJ. "Non-contrast enhanced 4D dynamic MRA with golden angle radial acquisition and k-space weighted image contrast (KWIC) reconstruction", Magn Reson Med. 2013 Dec 12. doi: 10.1002/mrm.25057. [Epub ahead of print]
• Sharma M, Hu P, Rapacchi S, Ennis DB, Thomas MA, Lee P, Kupelian P, Sheng K. "Accelerating dynamic MRI for lung tumor tracking based on low-rank decomposition in the spatial-temporal domain, a feasibility study based on simulation and preliminary prospective under-sampled MRI", Int J Radiat Oncol Biol Phys, 2014;88(3):723-31
• Wang D, Shao J, Rapacchi S, Middione M, Ennis DB, Hu P. "Phase contrast MRI with flow compensation view sharing", Magn Reson Med. 2015 Feb;73(2):505-13. doi: 10.1002/mrm.25133. Epub 2014 Feb 14.
• Shao J, Nguyen KL, Natsuaki Y, Spottiswoode B, Hu P. "Instantaneous signal loss simulation (InSiL) – An improved algorithm for myocardial T1 mapping using the MOLLI sequence", J Magn Reson Imaging. 2015 Mar;41(3):721-9. doi: 10.1002/jmri.24599. Epub 2014 Feb 19.]
• Rapacchi S, Natsuaki Y, Plotnik A, Gabriel S, Laub G, Finn JP, Hu P. "Reducing view-sharing using compressed sensing in time-resolved contrast-enhanced magnetic resonance angiography", Magn Reson Med, 2014 (In Press).
• Gou S, Wu J, Liu F, Lee P, Rapacchi S, Hu P, Sheng K. “Feasibility of automated pancreas segmentation based on dynamic MRI”, Br J Radiol. 2014 Dec;87(1044):20140248. doi: 10.1259/bjr.20140248. Epub 2014 Oct 1.
• Han F, Rapacchi S, Khan S, Ayad I, Salusky I, Gabriel S, Plotnik A, Finn JP, Hu P. “Four-Dimensional, Multiphase, Steady-State Imaging with Contrast Enhancement (MUSIC) in the Heart: a Feasibility Study in Children”, Magn Reson Med. 2015 Oct;74(4):1042-9. doi: 10.1002/mrm.25491. Epub 2014 Oct 9.