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UCLA Prostate Imaging and Treatment

UCLA Prostate Imaging and Treatment

UCLA Prostate Imaging and Treatment
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UCLA Prostate Imaging and Treatment

About Us

About Us

About Us

  • Case Studies
    • Radiation Therapy
    • Small Volume Low Grade Disease
    • Active Surveillance
    • Example of Change to Nerve Sparing
    • Extracapsular Extension and Seminal Vesicle Invasion
    • Dynamic Contrast-Enhancement for Biochemical Failure
    • MR-Guided Targeted Biopsy
    • Benign Disease (Infertility)
  • Clinical Trials
  • CME Course
  • Research Publications
  • Case Studies
  • Clinical Trials
  • CME Course
  • Research Publications
  • Radiation Therapy
  • Small Volume Low Grade Disease
  • Active Surveillance
  • Example of Change to Nerve Sparing
  • Extracapsular Extension and Seminal Vesicle Invasion
  • Dynamic Contrast-Enhancement for Biochemical Failure
  • MR-Guided Targeted Biopsy
  • Benign Disease (Infertility)
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  5. Small Volume Low Grade Disease

Small Volume Low Grade Disease

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History

  • 60 year-old
  • PSA 3.6
  • 5 of 6 right biopsies GS3+3

Imaging

Small Volume Low Grade Disease

 

LEFT: Apparent diffusion coefficient (ADC) map: moderately restricted diffusion
CENTER: T2 Weighted imaging: ill-defined low signal (yellow arrow) does not abut the prostate capsule
RIGHT: Perfusion map: focally increased perfusion

 

nnn
LEFT
: Perfusion time-intensity curve: type III (washout) curve is highly suspicious
mmm
RIGHT
: Whole-mount pathology: two low-grade (Gleason Score 3+3=6) tumors do not involve capsule

 

Advantage: UCLA Prostate MRI

  • Although less sensitive for low-grade disease, MRI can help with determining extent and determination whether surveillance or definitive treatment is warranted.
  • Diffusion weighted imaging (such as Siemens REVEAL) with multiple b-values allows for high contrast-to-background on ADC map and computation of high b-value images
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