Dr. Pajonk was recruited to UCLA in 2005. He was previously head of the Clinical and Experimental Radiation Biology Research Section at the University Hospital Freiburg, Germany. Dr. Pajonk received his MD at the University Freiburg and his PhD at the Universities of Freiburg, Germany and Bale, Switzerland. From 1998 to 1999 he joined the Department of Radiation Oncology at the David Geffen School of Medicine at UCLA as a postdoctoral fellow. In 2002 he received his habilitation and venia legendi from the University of Freiburg, Germany.
Dr. Pajonk’s Research Interests
Dr. Pajonk’s laboratory has a long-standing interest in signal transduction in cancer and the role of the 26S proteasome in malignancies. Very early on his laboratory started working with prospectively identified cancer stem cells and since then have made seminal discoveries including the intrinsic radioresistance of breast cancer stem cells and underlying mechanisms, developed innovative new techniques to image, track and target cancer stem cells in vitro and in vivo, and uncovered fundamental differences in the metabolic state of cancer stem cells and their progeny.