Research Spotlight on ASTRO's 2017 Junior Faculty Award Winner, Erina Vlashi, PhD
September 18, 2017 -- Only one junior faculty member is selected for the ASTRO Junior Faculty Career Research Training Award (JFA) every year, which provides $100,000 annually for two years. The ASTRO Junior Faculty Career Research Training Award (JFA) gives early career physicians and researchers the opportunity to develop careers and focus on research relevant to radiation oncology, biology or physics.
ASTROnews Spring 2018 | www.astro.org
Coping With Her Mother's Cancer, Girl Sells Bracelets to Raise Awareness
Lolita Lopez & Liana Clayton -- Liana's Looms of Love raises money for cancer therapy. Liana Clayton is watching her mother fight to survive cancer first-hand. She wanted to help her mother, Che Clayton, who's received rounds of painful treatment for breast cancer, but ended up helping many more people. Liana sells her colorful, handmade bracelets to raise awareness and give back to the doctors who helped her family cope with the disease. Lolita Lopez reports for NBC4 News.
View Story on NBC 4
State-of-the-Art “Same Day” HDR Brachytherapy
Drs. Kamrava & Demanes -- UCLA brachytherapy takes big step forward by opening a State-of-the-Art anesthesia ready brachytherapy procedure suite. It is equipped with a portable CT scanner (AIRO) as well as real-time ultrasound planning allowing for safe, precise and efficient treatment. This level of resource is limited to only a few centers in the United States. We will do prostate, breast, lung, esophagus, gynecologic and other kinds of brachytherapy procedures using advanced imaging technology. It is a major improvement in efficiency and patient comfort. Patients will no longer routinely have to stay overnight.
Clinical Trial: Predicting Radiation Toxicity
Dr. Percy Lee -- DxTerity Wins Contract to Develop a Test for Predicting Radiation Toxicity. DxTerity will be collaborating with Dr. Percy Lee, Chief of Thoracic and GI Radiation Oncology at the University of California Los Angeles (UCLA) Jonsson Comprehensive Cancer Center. Dr. Lee will serve as co-Principal Investigator and brings his clinical expertise in multiple radiotherapeutic modalities used for the treatment of cancer.
View news release
One Treatment One Day
At UCLA, we have the resources to deliver radiation therapy in the operating room. Intraoperative radiation therapy shortens the treatment time from 6.5 weeks to 1 day. In our clinic, Intra-Operative Radiation Therapy (IORT) is being used to treat breast cancer. It is a newer form of partial breast radiation which is done from start to finish in the operating room in conjunction with the surgery.
Ask our brachytherapy team if IORT is right for you
UCLA Radiation Oncology Earns ACR Accreditation
May, 2013 -- UCLA Radiation Oncology has been awarded a three-year term of accreditation in radiation oncology as the result of a recent review by the American College of Radiology (ACR). The ACR is the nation’s oldest and most widely accepted radiation oncology accrediting body, with nearly 500 accredited sites, and 25 years of accreditation experience.
Accreditation FAQs acr.org
Ovarian Cancer Care Often Substandard
Mar 12, 2013 -- A new study presented this week at a meeting of the Society of Gynecologic Oncology in Los Angeles found two out of every three women diagnosed with ovarian cancer could be getting better treatment. “A general surgeon who doesn't see much ovarian cancer may not have the capability to do this procedure,” said Dr. Ursula Matulonis, director of the gynecological oncology program at the Dana-Farber Cancer Institute.
Story on nbcnews.com
ASTRO Announces 2012 Fellows
Jul 26, 2012, Dr. Michael Steinberg on astro.org -- The American Society for Radiation Oncology (ASTRO) has named its 2012 class of Fellows. Professor and chairman of the department of radiation oncology at UCLA, Michael L. Steinberg, MD, FASTRO, ASTRO president said "This year's class clearly stood out because of their distinct contributions to ASTRO and to the field of radiation oncology as a whole."
Story on expertclick.com
ASTRO Publishes Safety is No Accident: A Framework for Quality Radiation Oncology and Care
Jul 18, 2012, Dr. Michael Steinberg on astro.org -- The American Society for Radiation Oncology (ASTRO) is proud to announce the publication of Safety is No Accident: A Framework for Quality Radiation Oncology and Care, a comprehensive book detailing minimum recommended guidelines for radiation oncology practices.
NEW AT UCLA - TomoTherapy, New Cancer Treatment at UCLA
Jul 11, 2012, UCLA Radiation Oncology is excited to announce the addition of TomoTherapy HD to our compliment of machines! Now more than ever, UCLA has the breadth in technology paired with our expert physicians and treatment team to create the most appropriate personalized treatment plan that is right for you.
High-Dose-Rate Prostate Brachytherapy Consistently Results in High Quality Dosimetry
May 31, 2012, Dr. Kamrava & Dr. Demanes on redjournal.org -- HDR brachytherapy allows the physician to consistently achieve complete prostate target coverage and maintain normal tissue dose constraints for organs at risk over a wide range of target volumes.
Story on redjournal.org
We’re Growing! Our New Santa Monica Location is Now Open
May 01, 2012, We’re expanding our services to provide you with a new convenient location in Santa Monica. Department of Radiation Oncology, 1223 16th Street, Santa Monica, CA 90404. Tel: (424) 259-8777
Story on smmirror.com | Story on UC Health
Donna Karan Healing Program Coming Soon
Mar 19, 2012, Donna Karan -- KCBS Channel 2 aired a March 19 story on fashion designer Donna Karan's Urban Zen Integrative Therapy program, which uses Eastern healing techniques to enhance the care of hospital patients at Ronald Reagan UCLA Medical Center. The UCLA Department of Radiation Oncology will be offering this program to cancer patients starting in May!
Webcast UCLA YouTube Video
The New War on Cancer
Mar 15, 2012, Dr. Chris King -- The UCLA Department of Radiation Oncology is one of the first centers in the nation to offer SBRT for prostate cancer. Dr. Chris King is one of the leading experts in SBRT for prostate cancer at UCLA. Men with localized disease can now complete radiation in just two weeks, with no surgery. Stereotactic body radiation therapy (SBRT) delivers high doses of radiation to targeted areas in just five sessions on alternate days.
Story on latimes.com | SBRT for Prostate Cancer | Savi Center of Excellence
The New TrueBeam™ System
Feb 28, 2012, Advanced Radiotherapy System at UCLA -- Powerful cancer treatments with pinpoint accuracy and precision. Opening up treatment options for people with cancer, it targets tumors with accuracy measured in millimeters. With its power and flexibility, clinicians can develop treatments that are best suited for patients’ individual circumstances. TrueBeam combines imaging, beam delivery and sophisticated motion management to accurately and precisely target tumors with speed.
TrueBeam System Overview | Frequently Asked Questions
New IUO Website - Institute of Urologic Oncology
Feb 21, 2012, UCLA scientists and physicians developing leading-edge therapies for the treatment of prostate, kidney, bladder and testicular cancers. Radiation Oncology faculty Dr. Christopher King and Dr. Patrick Kupelian are proud to be part of the institute.
IUO Expert Team | New IUO website
Anti-cancer Treatment Generates Therapy-resistant Cancer Stem Cells from Less Aggressive Breast Cancer Cells
Feb 14, 2012, By Kim Irwin, Dr. Frank Pajonk -- Researchers from UCLA’s Jonsson Comprehensive Cancer Center Report for the First Time that Radiation Transforms Cancer Cells into Dangerous Stem Cells. Breast cancer stem cells are thought to be the sole source of tumor recurrence and are known to be resistant to radiation therapy and don’t respond well to chemotherapy. “What is really exciting about this study is that it gives us a much more complex understanding of the interaction of radiation with cancer cells that goes far beyond DNA damage and cell killing,” Dr Frank Pajonk said.
Patient Profile: Grace Suomi—Young Cancer Patient Battles Ewing’s Sarcoma
Nov 01, 2011, By Kim Irwin, Clare & Grace Suomi -- Grace Suomi was five and had just finished the year at Curtis School in Los Angeles when she started exhibiting strange symptoms. They started with terrible nightmares that caused the child to thrash and scream in her sleep. Her mother, Clare Suomi, attributed the bad dreams to anxiety, as Grace was scheduled to start camp soon. Then her right jaw started hurting, her appetite disappeared and her personality seemed somehow off.
Story on cancer.ucla.edu | More patient stories
UCLA Health System - Jonsson Comprehensive Cancer Center to Acquire ViewRay System
Sep 27, 2011, PRNewswire, Dr. Michael Steinberg -- UCLA Health System and Jonsson Comprehensive Cancer Center (JCCC) will become the third oncology research center in the world to acquire a radiotherapy system from ViewRay™, Inc., a privately held medical device company. The ViewRay system will enable researchers at UCLA to “continue to meet our mission of fostering patient-centered care while pursuing better treatments and cures for cancer,” said Michael Steinberg, MD.
prnewswire.com | PDF Version | DigitalJournal | DigitalJournal
Shorter Course of Radiation May Treat Prostate Cancer
Sep 27, 2011, Michael Steinberg, MD -- Researchers See Potential Benefits for a 5-Week Course of Radiation Therapy
By Charlene Laino, WebMD, Health News. A shorter, cheaper, and more convenient five-week course of radiation appears to work just as well as the traditional seven-and-one-half week schedule for men with prostate cancer.
Story on WebMD.com | PDF Version
Metabolic State of Brain Cancer Stem Cells is Significantly Different Than That of Differentiated Cancer Cells
Sep 6, 2011, Dr. Frank Pajonk -- The metabolic state of glioma stem cells, which give rise to deadly glioblastomas, is significantly different from that of the brain cancer cells to which they give birth, a factor which helps those stem cells avoid treatment and cause recurrence later.
Story on cancer.ucla.edu | PDF Version | Story on sciencedaily.com
Drs. Kamrava and McCloskey -- Dr. Mitchell Kamrava and Dr. Susan McCloskey joined the prestigious Radiation Oncology Clinical Faculty on July 1, 2011. Dr. Kamrava will be the second faculty to join the Brachytherapy program at UCLA. Dr. McCloskey is known for her health policy research and will be focusing on Breast and many other cancers.
More about Dr. Kamrava | More about Dr. McCloskey
What’s Your Radiation Risk?
April 04, 2011, Dr. Keisuke Iwamoto on lifescript.com -- How serious is the risk of radiation exposure from Japan? Get the facts about contamination of air, water and food – and read why experts say the chances of being harmed by overseas radiation still are minuscule.PDF version | Article on lifescript.com
Myths About Japanese Radiation Dispelled
March 30, 2011, Dr. Keisuke Iwamoto on UCLA News Week -- In this week's video news digest, radiation biologist Keisuke Iwamoto dispels myths about radioactive fallout from the Fukushima nuclear plant in Japan. Iwamoto, an associate professor of radiation oncology, studies the effects of radiation on the human body.View Webcast | Story on UCLA Newsroom
Can Japan's Nuclear Fallout Affect The U.S.?
March, 2011, Dr. William McBride on KTLA.com -- Can Japan's Nuclear Fallout Affect The U.S.? Cher Calvin Reports - KTLA
In the wake of Japan's deadly earthquake, tsunami and nuclear explosions, now there's new concern about whether radioactive material could reach the U.S.View Webcast | Video Gallery
Japan Earthquake: Could Nuclear Power Plant Radiation Reach L.A?
March 17, 2011, Dr. William McBride on blogs.laweekly.com -- Update: Minor amounts of radiation are projected to reach SoCal by Friday, after the jump. Could radiation from Japan's quake-stricken nuclear power plants reach Los Angeles? It's a long shot. But a look at Pacific jet stream animation shows that what happens in Japan doesn't stay in Japan.
Live chat: The potential health hazards of radiation with Keisuke Iwamoto
March 17, 2011, Doctor Keisuke Iwamoto on latimes.com -- Worried about the health effects of radiation exposure? Get answers during a live chat with Keisuke Iwamoto, on the faculty of the Division of Molecular and Cellular Oncology at UCLA. Iwamoto is also an adjunct associate professor of experimental radiation oncology.
PDF version | Live Chat on latimes.com
Doctors Try to Ease Radiation Exposure Fears
March 16, 2011, Dr. William McBride on cbn.com -- With several Japanese nuclear plants crippled by Friday's earthquake and tsunami, radiation poisoning -- or Acute Radiation Syndrome -- has become a real threat for residents of the island nation. While the threats of radiation mount, doctors hope to ease the fears of those affected.
Fears Radiation Will Spread From Japan to Calif.
March 26, 2011, Dr. Keisuke Iwamoto on KABC -- By Lisa Hernandez and Miriam Hernadez SANTA MONICA, Calif. (KABC) -- The fear that radiation will spread from Japan to the U.S. has sparked a run on potassium iodide pills, even though experts say that the threat of exposure is very remote.
Radiation exposure: What we know from Hiroshima and Nagasaki
March 15, 2011, Dr. William McBride on latimes.com -- Radiation exposure is sadly all too familiar to the people of Japan. The health effects of radiation were poorly understood until the United States dropped atomic bombs on the cities of Hiroshima and Nagasaki toward the end of World War II. Prior to that time, scientists had widely mixed views on the impact of radiation exposure.
Radiation Risk Adds to Fears in Japan Disaster
March 14, 2011, UCLA Scientist William McBride, on KABC -- LOS ANGELES (KABC), There was yet another explosion at Japan's Fukushima nuclear facility Monday, prompting new fears of more radiation being released. A radiation expert in L.A. says while the situation is critical, there are things that can be done to minimize the danger from exposure.
High-Dose-Rate Brachytherapy Gets Patients Back to Normal Living More Quickly
Jeffrey Demanes, MD, Prostate Cancer Treatment and Breast Cancer Treatment -- The goal of brachytherapy, or internal radiation therapy, is to precisely target the radiation exposure to the tumor where it is needed and avoid surrounding healthy tissues.
Brachytherapy Video | Download (PDF) | Brachytherapy Program
UCLA Radiation Oncologist and Cancer Researcher Receives Gold Medal, Highest Honor Bestowed by Radiation Oncology Society
Nov 10, 2010, Scientist William McBride, whose research focuses on the role of damage response to radiation in normal tissue and malignant tumors, has been given the Gold Medal award by the American Society for Radiation Oncology, the highest honor bestowed by the 10,000-member organization. McBride, director of the division of cellular and molecular oncology in the Department of Radiation Oncology at UCLA, received the award during organization’s 52nd annual meeting.
UCLA Grant to Develop Medical Countermeasures Against Radiological and Nuclear Attacks Renewed
Oct 14, 2010, William McBride, Radiation Oncologists Seeking to Discover Compounds that will Help Mitigate Damage to Immune System -- Researchers in the Radiation Oncology Department at UCLA’s Jonsson Comprehensive Cancer Center have received a $14 million grant to develop countermeasures that will help treat damage caused by radiological or nuclear threats such as a dirty bomb attack.
PDF version | globalsecuritynewswire.org | news-medical.net
Sep 08, 2010, Dr. Michael Steinberg -- The American Society for Radiation Oncology (ASTRO) announced UCLA's Michael L. Steinberg, MD, FASTRO as President-elect. ASTRO is the largest radiation oncology society in the world, with more than 10,000 members who specialize in treating patients with radiation therapies.
PDF version | www.astro.org
Irradiating the Brain Site That Harbors Stem Cells Improves Progression-free Survival in Patients with Deadly Cancers
July 22, 2010, Dr. Frank Pajonk -- Patients with deadly glioblastomas who received high doses of radiation that hit a portion of the brain that harbors neural stem cells had double the progression-free survival time as patients who had lower doses or no radiation targeting the area, a study from the Radiation Oncology Department at UCLA’s Jonsson Comprehensive Cancer Center has found.
Article on biomedcentral.com | sciencedaily.com | PDF version
The UCLA Department of Radiation Oncology is pleased to announce the appointment of Patrick Kupelian, MD
July 01, 2010, Patrick Kupelian, MD -- The UCLA Department of Radiation Oncology is pleased to announce the appointment of Patrick Kupelian, MD, Professor and Vice-Chair of Clinical Operations and Clinical Research. Dr. Kupelian comes to UCLA from MD Anderson Cancer Center in Orlando, FL, where he was the Chairman and Scientific Director of Research for Radiation Oncology.
Dr. Jeffrey Demanes receives the American College of Radiation Oncology (ACRO) Gold Medal
February 26, 2010, Dr. Jeffrey Demanes MD -- The American College of Radiation Oncology honored Dr. Jeffrey Demanes MD, FACRO with the Gold Medal Award at this year's conference. Dr. Demanes specializes in brachytherapy. He pioneered the use of high-dose-rate brachytherapy in prostate, head and neck, breast, GI, and gynecologic cancer.
Radiation Oncology Patient Celebrates 100th Birthday
November 16, 2009, Doctors, nurses, technicians and other staff of the Radiation Oncology Department surprised patient Lydia Topalian with a party to celebrate her 100th birthday.
UCLA Has New Weapon in Battle Against Cancer
UCLA's Department of Radiation Oncology has acquired a new cancer-fighting device, allowing for higher doses of radiation in a smaller amount of time. They are the first center in the Los Angeles region to install the Novalis Tx, a non-invasive stereotactic radiosurgery mechanism that includes three imaging modalities.
In Vivo Imaging, Tracking and Targeting of Cancer Stem Cells
By Dr. Frank Pajonk -- Cancers contain a small population of so-called cancer stem cells. Their frequency varies between the different types of cancer, but it is generally thought to be in the order of 1 in 10,000 cells. These cells are the only cells, able to regrow the entire tumor after debulking surgery, chemotherapy, and radiation treatment while all of their progeny lack this ability. Additionally, cancer stem cells are relatively resistant to radiation therapy and highly resistant to established chemotherapeutic agents.
Resistance to Radiation Therapy (RT)
By Dr. Nicholas Cacalano -- Resistance to radiation therapy (RT) is a hallmark of deadly cancers such as glioblastoma multiforme (GBM), which has a dismal 2-3% five-year survival rate. Much effort has been focused on developing novel molecular therapies that sensitize tumors to RT and improve patient survival and quality of life. Researchers in the Radiation Oncology Department at UCLA have found that a molecule called Suppressor of Cytokine Signaling (SOCS)-3, is overexpressed in radioresistant glioblastoma multiforme (GBM), and confers protection from radiation-induced cell death.
Diana L. Gage, MD, PhD, Radiation Oncology, Ronald Reagan UCLA Medical Center, Los Angeles, Calif.
RSNA Research Resident Grant -- Radiosensitization with Anti-VEGF in Glioblastoma Cells, Grants and Awards 2008
Glioblastoma is the most aggressive form of brain cancer, accounting for approximately 40% of all primary malignant brain tumors. Despite optimal treatment with surgery, radiotherapy and chemotherapy, the prognosis for these patients remains poor. Adjuvant temozolomide with radiotherapy serves as the standard of care for newly-diagnosed cases.
Brian Yeh, MD, Radiation Oncology, Ronald Reagan UCLA Medical Center, Los Angeles, Calif. RSNA Research Resident Grant
The Role of TNF-Alpha Signaling in Normal Brain Tissue Response to Radiation -- Radiation therapy is an important treatment modality for brain tumors, but the outcome is generally dismal. Most patients with glioblastoma succumb to the disease within a year. Increasing radiation dose increases the time to recurrence for these patients, but at the cost of increased complications. Patients receiving whole brain irradiation for metastatic tumors also suffer a high rate of neurological complications, which can be severely debilitating.
UCLA Researcher Co-Authors New PET/CT Head and Neck Study
Percy Lee, MD -- Assistant Professor and Director of the Stereotactic Body Radiation Therapy (SBRT) program at UCLA was a co-author with investigators from Stanford University on a study in-press in the International Journal of Radiation Oncology, Biology and Physics (IJROBP), the top radiation oncology journal. In this study, 85 head and neck patients received 18-flurodeoxyglucose positron emission tomography (18- FDG PET/CT)-guided chemoradiotherapy.
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