A Study That Researches the Effects of Radiation Prior to Getting a Prostatectomy
Technical Title: Phase I Trial of Preoperative Adjuvant Stereotactic Body Radiotherapy for Patients at High Risk of Local Failure after Prostatectomy
Existing data shows that some patients who only undergo prostatectomy (removal of the prostate) have an increased risk of tumor recurrence (return of your cancer after treatment) as compared to patients who undergo prostatectomy in combination with radiation. This study is designed to discover whether or not men with prostate cancer who receive radiation therapy prior and in addition to prostatectomy can live longer, healthier lives than those patients who only receive prostatectomy as their first treatment.
Prior to prostatectomy, study patients will come to Radiation Oncology for a treatment planning session which requires a CT scan, then return about one week later to receive radiation to the pelvis on three separate occasions. Patients will return to Radiation Oncology for regular follow-up visits for at least one year, but may be asked to allow follow-up information to be gathered from other doctors for up to five years. At four different occasions, patients will be asked to provide blood samples solely for the purposes of long-term scientific research.
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