UCLA Division of Rheumatology conducts cutting-edge biomedical and health-related research studies that include both interventional and observational studies. Our clinical studies are sponsored/funded by National Institute of Health (NIH), pharmaceutical companies, and/or non-profit medical institutions/organizations.
Treatment/Interventional studies are those in which the research subjects are assigned to a treatment or intervention and their outcomes are measured.
Observational studies are those in which individuals are observed and their outcomes are measured by the study investigators.
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Rheumatoid Arthritis
Cholesterol
Dermatomyositis
Gout
Lupus
Psoriatic Arthritis
Scleroderma
Vasculitis
If you would like to get more information on any studies please call us at (310) 825-0096 or email rheumresearch@mednet.ucla.edu.
If you are interested in finding out more information of a particular study, please contact the study personnel.
Study Type | Title of Study | |
| Rheumatoid Arthritis | ||
| Treatment/ Interventional | *Multiple studies | Principal Investigators |
| Treatment/Interventional | Dietary Intervention on Rheumatoid Arthritis Assessed by Ultrasound in over weight patients Status: Open for Enrollment | Principal Investigator Veena K. Ranganath, MD, MS For more information, please contact (310) 825-9956 |
| Treatment/Interventional | Musculoskeletal Ultrasound Predicting Therapeutic Response in Tofacitinib in Rheumatoid Arthritis Patients Status: Open for Enrollment | Principal Investigator Veena K. Ranganath, MD, MS For more information, contact (310) 825-9956 |
| Observational | HDL (Carotid Study): Evaluation of HDL function in patients with and without Rheumatic Disease Status: Open for Enrollment | Principal Investigator Christina Charles, MD For more information, contact Jeraldine Guzman (310) 825-4744 |
| Treatment | BMS: A Placebo-Controlled Study to Evaluate the Effect, Safety, and Characteristics of Abatacept in Subjects with Rheumatoid Arthritis with Hepatitis B. Status: Open for Enrollment | Principal Investigator For more information, contact Nashla Barroso (310) 825-9682 |
| Treatment | Use of ACTHAR in Rheumatoid Arthritis Related Flares. Status: Open for Enrollment | Principal Investigator Veena K. Ranganath, MD, MS For more information, contact (310) 825-9956 |
| Cholesterol | ||
| Observational | HDL Function in Patients With and Without Rheumatic Disease (Investigatory) | Principal Investigator Christina Charles-Schoeman, MD For more information, contact Jeraldine Guzman (310) 825-4744 |
| Dermatomyositis | ||
| Treatment | Prospective, Double-blind, Randomized, Placebo-Controlled Phase III Study Evaluating Efficacy and Safety of Octagam 10% in Patients with Dermatomyositis Status: Open for Enrollment | Principal Investigator Christina Charles-Schoeman, MD For more information, contact Jeraldine Guzman |
| Gout | ||
| Observational | Gout Cholesterol Study: A study to evaluate the association between gout and cholesterol. Patients undergo blood draw and Dual Energy CAT Scan (to measure amount of gouty deposits). | Principal Investigators John FitzGerald, MD For more information, contact (310) 794-5100 |
| Lupus | ||
| Treatment | Efficacy of Abatacept (Orencia®) in inflammatory Polyarthritis of Systemic Lupus Erythematosus (SLE) Status: Open for Enrollment | Principal Investigator Bevra Hahn, MD For more information contact |
| Treatment | Rituximab plus Cyclophosphamide followed by Belimumab for the treatment of Lupus Nephritis (CALIBRATE) Status: Open for Enrollment | Principal Investigators Maureen McMahon, MD For more information contact |
| Treatment | Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis (STOP RA) Status: Open for Enrollment | Principal Investigators For more information contact |
| Treatment | A Multicentre, Randomised, Double-blind, Placebo-controlled, Phase 2 study Evaluating the Efficacy and Safety of Anifrolumab in Adult Subjects with active Proliferative Lupus Nephritis Status: Open for Enrollment | Principal Investigator Jennifer Grossman, MD For more information, contact Mia Vasquez-Gutierrez (310) 825-6461 |
| Treatment | A Multicentre, Randomised, Double-blind, Placebo-controlled, Phase 3 Study Evaluating Efficacy and Safety of Anifrolumab in Adult subjects with Active Systemic Lupus Erythematosus (SLE) Status: Open for Enrollment | Principal Investigator Jennifer Grossman, MD For more information, contact Mia Vasquez-Gutierrez (310) 825-6461 |
| Observational | Biomarkers in Lupus Status: Open for Enrollment | Principal Investigator Ram Raj Singh, MD For more information contact Ram Raj Singh, MD |
| Observational | The Role of Gender Factors in Lupus and Autoimmunity Status: Open for Enrollment | Principal Investigator For more information contact |
| Observational | Autoimmunity Characteristics in Patients with Systemic Lupus Erythematosus versus Health Controls Status: Open for Enrollment | Principal Investigator For more information contact |
| Observational | Observational, Mechanisms of Inflammation and Immune Response in Skin Dermatoses. Status: Open for Enrollment | Principal Investigator For more information contact |
| Treatment/ Interventional | *Multiple studies Status: Open for Enrollment | Principal Investigators For more information, contact Mia Vasquez-Gutierrez (310) 825-6461 |
| Treatment | Novartis: CAIN457F2354 AIN457/Secukinumab (Cosentyx) for Active Psoriatic Arthritis. Status: Open for Enrollment | Principal Investigator For more information, contact Nashla Barroso (310) 825-9682 or Jeraldine Guzman (310) 825-4744 |
| Scleroderma | ||
| Treatment/ Interventional | *Multiple studies | Principal Investigator TBD |
| Observational | SPIN: The Scleroderma Patient-Centered Intervention Network (SPIN) Cohort Status: Open for Enrollment
| Principal Investigator For more information, contact Nashla Barroso (310) 825-9682 |
| Observational | Blood and Skin Biopsy Donation: A research study to define the differences in Immune Responses in skin from patients with an autoimmune or inflammatory condition Status: Open for Enrollment | Principal Investigator For more information, contact |
| Other | PHAROS: Outcome Studies in Systemic Sclerosis: A Prospective Database of Echocardiograms and PFTs on Patients with Limited Scleroderma (Standard of Care) Status: Open for Enrollment | Principal Investigators For more information, contact Nashla Barroso (310) 825-9682 |
| Observational | Quality of Life: Quality of Life of people with scleroderma: Health values and minimally important differences of people with scleroderma Status: Open for Enrollment | Principal Investigator Suzanne Kafaja, MD For more information, contact Nashla Barroso (310) 825-9682 |
| Treatment | BRAVOS ITN075AI: Study of an Investigational Drug, Brentuximab Vedotin, for Diffuse Cutaneous Systemic Sclerosis. Status: Open for Enrollment | Principal Investigator For more information, contact Nashla Barroso (310) 825-9682 |
| Treatment | Cumberland: A Study to Assess the Safety and Efficacy of Ifetroban in Patients with Diffuse Systemic Sclerosis or Systemic Sclerosis-Associated Pulmonary Arterial Hypertension. Status: Open for Enrollment | Principal Investigator For more information, contact Nashla Barroso (310) 825-9682 |
| Observational | GRASP: Genome Research in African American Scleroderma Patients (GRASP) Status: Open for Enrollment | Principal Investigator For more information, contact Nashla Barroso (310) 825-9682 or Jeraldine Guzman (310) 825-4744 |
| Treatment | SLS III: A Combination study of Pirfenidone (PFD) with Mycophenolate (MMF) for Treating Scleroderma-Related Lung Disease. Status: Open for Enrollment | Principal Investigator Co-Investigator Suzanne Kafaja, MD For more information, contact Nashla Barroso (310) 825-9682 |
| Treatment | STAT: Scleroderma Treatment with Autologous Transplant (STAT). A study of a Scleroderma Treatment Using the Patient's Own Blood Stem Cells. Status: Open for Enrollment | Principal Investigator For more information, contact Nashla Barroso (310) 825-9682 or Jeraldine Guzman (310) 825-4744 |
| Vasculitis | ||
| Treatment | A Randomized, Double-Blind, Active-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of CCX168 (Avacopan) in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis Treated Concomitantly with Rituximab or Cyclophosphamide/Azathioprine Lay person title: Study of an Investigaional Treatment for ANCA Vasculitis This is a clinical trial evaluating an investigational product called CCX168 (also known as Avacopan) in patients with granulomatosis with polyangiitis (GPA, formerly called Wegener’s disease) and microscopic polyangiitis (MPA). Status: Open for Enrollment | Principal Investigator For more information contact, Tandy Ramirez 310-206-0994 |
| Other | Clinical Transcriptomics in Systemic Vasculitis (CUTIS). This is a multi-center study evaluating new ways to distinguish different forms of vasculitis that can affect the skin by evaluation of biopsy and laboratory testing. Status: Open for Enrollment | Principal Investigator Tanaz Kermani, MD (Rheumatology and Dr. Bonita Kozma (Dermatology) For more information, contact Tandy Ramirez at 310-206-0994 |
