Alexander Hoffman

Alexander Hoffmann, PhD

Professor, Department of Microbiology, Immunology and Molecular Genetics
Director, Graduate Program in Bioinformatics and Systems Biology



Scientific Interests

The research of Dr. Alex Hoffmann's laboratory focuses on the signaling systems that ensure that cells respond to noxious stimuli and pathogens appropriately, and how they change during cell differentiation and carcinogenesis.

Highlighted Publications

Mulero MC, Ferres-Marco D, Islam A, Margalef P, Pecoraro M, Toll A, Drechsel N, Charneco C, Davis S, Bellora N, Gallardo F, Lopez-Arribillaga E, Asensio-Juan E, Rodilla V, Gonzalez J, Iglesias M, Shih V, Mar Alba M, Di Croce L, Hoffmann A, Miyamoto S, Villa-Freixa J, Lopez-Bigas N, Keyes WM, Dominguez M, Bigas A, Espinosa L. Chromatin-bound IkappaBalpha regulates a subset of polycomb target genes in differentiation and cancer. Cancer Cell. 2013 Aug 12;24(2):151-66. doi: 10.1016/j.ccr.2013.06.003. Epub 2013 Jul 11.