Donald M. Lamkin, PhD
Dr. Donald Lamkin's research focuses on biobehavioral mechanisms in cancer control. Using preclinical models of cancer and bioinformatic analysis of functional genomics, he rigorously tests hypotheses on how stress physiology may affect progression of malignancy, particularly in regard to the sympathetic nervous system. With an eye toward translation to clinical populations, Lamkin also collaborates with JCCC clinical investigators, utilizing methods in microscopy and laser microdissection to test for links among tumor gene expression, protein expression and patient experience of stress-related psychological and social factors.
Bower JE, Shiao SL, Sullivan P, Lamkin DM, Atienza R, Mercado F, Arevalo J, Asher A, Ganz PA, Cole SW. Prometastatic Molecular Profiles in Breast Tumors From Socially Isolated Women. JNCI Cancer Spectr. 2018 Jul;2(3):pky029. doi: 10.1093/jncics/pky029. Epub 2018 Jul 19.
Chun K, Capitanio JP, Lamkin DM, Sloan EK, Arevalo JM, Cole SW. Social regulation of the lymph node transcriptome in rhesus macaques (Macaca mulatta). Psychoneuroendocrinology. 2017 Feb;76:107-113. doi: 10.1016/j.psyneuen.2016.10.029. Epub 2016 Nov 14.
Lamkin DM, Ho HY, Ong TH, Kawanishi CK, Stoffers VL, Ahlawat N, Ma JCY, Arevalo JMG, Cole SW, Sloan EK. Beta-Adrenergic-stimulated macrophages: Comprehensive localization in the M1-M2 spectrum. Brain Behav Immun. 2016 Oct;57:338-346. doi: 10.1016/j.bbi.2016.07.162. Epub 2016 Jul 30.
Lamkin DM, Sung HY, Yang GS, David JM, Ma JC, Cole SW, Sloan EK. Alpha2-Adrenergic blockade mimics the enhancing effect of chronic stress on breast cancer progression. Psychoneuroendocrinology. 2015 Jan;51:262-70. doi: 10.1016/j.psyneuen.2014.10.004. Epub 2014 Oct 12.
Lamkin DM, Sung HY, Yang GS, David JM, Ma JC, Cole SW, Sloan EK. Alpha-2-Adrenergic blockade mimics the enhancing effect of chronic stress on breast cancer progression. Psychoneuroendocrinology. 2015 Jan;51:262-70. doi: 10.1016/j.psyneuen.2014.10.004. Epub 2014 Oct 12.