Hong Zhou, PhD

Hong Zhou, PhD

Professor, Department of Microbiology, Immunology, and Molecular Genetics





Computer Science, Applied Mathematics, and Informatics, Gulf Coast Consortia, 1997


PhD, Baylor College of Medicine, Houston, TX, 1995
MS, University of Science and Technology of China, Hefei, P.R. China, 1989
BS, University of Science and Technology of China, Hefei, P.R. China, 1986

Scientific Interests

Dr. Hong Zhou is the founding director of the Electron Imaging Center for Nanomachines at UCLA and a professor in the Department of Microbiology, Immunology and Molecular Genetics. His group uses innovative cryogenic electron microscopy (cryoEM) and tomography (cryoET) to determine 3D structures of tumor viruses and protein-nucleic acid complexes involved in cancers.  

Highlighted Publications

Gong D, Dai X, Jih J, Liu YT, Bi GQ, Sun R*, Zhou ZH*. (2019) DNA-Packing Portal and Capsid- Associated Tegument Complexes in the Tumor Herpesvirus KSHV. Cell. 178(6):1329-1343.e12. doi: 10.1016/j.cell.2019.07.035. PMCID: PMC6753055

Li X, Liu S, Zhang L, Issaian A, Hill RC, Espinosa S, Shi S, Cui Y, Kappel K, Das R, Hansen KC, Zhou ZH*, Zhao R*. 2019. A unified mechanism for intron and exon definition and back-splicing. Nature 573, 375–380 doi:10.1038/s41586-019-1523-6. PMCID: PMC6939996.

Liu, W., Y. Cui, C. Wang, Z. Li, D. Gong, X. Dai, G. Q. Bi, R. Sun and ZH Zhou* (2020). Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus. Nat Microbiol 5, 1285-1298, doi:10.1038/s41564-020-0758-1. PMCID: PMC7546529

He, Y., Y. Wang, B. Liu, C. Helmling, L. Susac, R. Cheng, Z.H. Zhou* and J. Feigon* (2021). Structures of telomerase at several steps of telomere repeat synthesis. Nature 593(7859): 454- 459. doi: 10.1038/s41586-021-03529-9. PMID: 33981033.

Zhou K, Si Z, Tso J, Luo M, Zhou ZH* (2022) Atomic model of vesicular stomatitis virus and mechanism of assembly. Nat Commun.13(1):5980. doi: 10.1038/s41467-022-33664-4. PMID: 36216930; PMCID: PMC9549855.