Hsian-Rong Tseng, PhD
Dr. Hsian-Rong Tseng's research seeks to develop microfluidic technology and to utilize this technology to address important issues in the fields of molecular imaging, cancer biology and chemistry. His research group has recently developed a variety of integrated microfluidic circuits for highly efficient radiolabeling reactions and cell-sorting processes, as well as a prototype nanoelectronic sensor that have the potential application in cancer diagnosis.
Zhao L, Lu YT, Li F, Wu K, Hou S, Yu J, Shen Q, Wu D, Song M, Ouyang WH, Luo Z, Lee T, Fang X, Shao C, Xu X, Garcia MA, Chung LW, Rettig M, Tseng HR, Posadas EM. High-Purity Prostate Circulating Tumor Cell Isolation by a Polymer Nanofiber-Embedded Microchip for Whole Exome Sequencing. Adv Mater. 2013 Mar 26. doi: 10.1002/adma.201205237. [Epub ahead of print]
Lu YT, Zhao L, Shen Q, Garcia MA, Wu D, Hou S, Song M, Xu X, Ouyang WH, Ouyang WW, Lichterman J, Luo Z, Xuan X, Huang J, Chung LW, Rettig M, Tseng HR, Shao C, Posadas EM. NanoVelcro Chip for CTC enumeration in prostate cancer patients. Methods. 2013 Dec 1;64(2):144-52. doi: 10.1016/j.ymeth.2013.06.019. Epub 2013 Jun 29.
Lee JH, Chen KJ, Noh SH, Garcia MA, Wang H, Lin WY, Jeong H, Kong BJ, Stout DB, Cheon J, Tseng HR. On-demand drug release system for in vivo cancer treatment through self-assembled magnetic nanoparticles. Angew Chem Int Ed Engl. 2013 Apr 15;52(16):4384-8. doi: 10.1002/anie.201207721. Epub 2013 Mar 20.
Hou S, Zhao L, Shen Q, Yu J, Ng C, Kong X, Wu D, Song M, Shi X, Xu X, OuYang WH, He R, Zhao XZ, Lee T, Brunicardi FC, Garcia MA, Ribas A, Lo RS, Tseng HR. Polymer nanofiber-embedded microchips for detection, isolation, and molecular analysis of single circulating melanoma cells. Angew Chem Int Ed Engl. 2013 Mar 18;52(12):3379-83. doi: 10.1002/anie.201208452. Epub 2013 Feb 21.
Hou S, Zhao H, Zhao L, Shen Q, Wei KS, Suh DY, Nakao A, Garcia MA, Song M, Lee T, Xiong B, Luo SC, Tseng HR, Yu HH. Capture and stimulated release of circulating tumor cells on polymer-grafted silicon nanostructures. Adv Mater. 2013 Mar 20;25(11):1547-51. doi: 10.1002/adma.201203185. Epub 2012 Dec 17.