Shimon Weiss DSc

Shimon Weiss, DSc

Professor, Department of Chemistry and Biochemistry



Contact Information

Scientific Interests

Dr. Shimon Weiss's research focuses on single molecule biophysics, particularly the application of single molecule spectroscopy: to biology and nanotechnology, dynamic structural biology, conformational dynamics of molecular machines, protein folding, protein-DNA and protein-protein interactions, single molecule enzymology, ultrahigh resolution & ultrahigh sensitivity fluorescence microscopy and spectroscopy and the physics and chemistry of mesoscopic (nano-scale) systems.

Highlighted Publications

Dertinger T, Colyer R, Vogel R, Heilemann M, Sauer M, Enderlein J, Weiss S. Superresolution optical fluctuation imaging (SOFI). Adv Exp Med Biol. 2012;733:17-21.

Kim S, Streets AM, Lin RR, Quake SR, Weiss S, Majumdar DS. High-throughput single-molecule optofluidic analysis. Nat Methods. 2011 Mar;8(3):242-5. Epub 2011 Feb 6

Dertinger T, Colyer R, Iyer G, Weiss S, Enderlein J. Fast, background-free, 3D super-resolution optical fluctuation imaging (SOFI). Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22287-92. Epub 2009 Dec 14

Bentolila LA, Weiss S. Single-step multicolor fluorescence in situ hybridization using semiconductor quantum dot-DNA conjugates. Cell Biochem Biophys. 2006; 45(1): 59-70.

Jager M, Nir E, Weiss S. Site-specific labeling of proteins for single-molecule FRET by combining chemical and enzymatic modification. Protein Sci. 2006; 15(3): 640-6.