Valerie Arboleda, MD, PhD
Dr. Valerie Arboleda's clinical and research interests are in the development of novel technologies that improve the diagnostic, prognostic and therapeutic role of clinically-based cancer sequencing. Her research lab explores the molecular mechanisms underlying how and which genomic variants, both germline and somatic, can alter cancer susceptibility and progression. She also studies genetic mutations in genes that are critical for epigenome regulation and progression of human cancer.
Contreras JR, Palanichamy JK, Tran TM, Fernando TR, Rodriguez-Malave NI, Goswami N, Arboleda VA, Casero D, Rao DS. MicroRNA-146a modulates B-cell oncogenesis by regulating Egr1. Oncotarget. 2015 May 10;6(13):11023-37.
Borges KS, Arboleda VA, Vilain E. Mutations in the PCNA-binding site of CDKN1C inhibit cell proliferation by impairing the entry into S phase. Cell Div. 2015 Mar 28;10:2. doi: 10.1186/s13008-015-0008-8. eCollection 2015.
Arboleda VA, Lee S. Lymphoma and gout coexisting in the same joint fluid. Blood. 2015 May 14;125(20):3213. No abstract available.
Arboleda VA, Lee H, Parnaik R, Fleming A, Banerjee A, Ferraz-de-Souza B, Delot EC, Rodriguez-Fernandez IA, Braslavsky D, Bergada I, Dell'Angelica EC, Nelson SF, Martinez-Agosto JA, Achermann JC, Vilain E. Mutations in the PCNA-binding domain of CDKN1C cause IMAGe syndrome. Nat Genet. 2012 May 27;44(7):788-92. doi: 10.1038/ng.2275.