Valerie Arboleda, MD, PhD

Valerie Arboleda, MD, PhD

Associate Professor, Department of Pathology and Laboratory Medicine, Department of Human Genetics
Associate Director of the Molecular Diagnostics Laboratory at UCLA




Pathology, Molecular Genetic

Institutional Affiliation

Ronald Reagan UCLA Medical Center
UCLA Medical Center, Santa Monica



Molecular Genetic Pathology, UCLA School of Medicine, 2017 - 2017


MD, David Geffen School of Medicine at UCLA, 2014
PhD, UCLA Graduate Program Human Genetics, 2012


Clinical Pathology, UCLA School of Medicine, 2014 - 2017

Board Certification

Pathology-Clinical, American Board of Pathology, 2017

Scientific Interests

Dr. Valerie Arboleda's clinical and research interests are in the development of novel technologies that improve the diagnostic, prognostic and therapeutic role of clinically-based cancer sequencing. Her research lab explores the molecular mechanisms underlying how and which genomic variants, both germline and somatic, can alter cancer susceptibility and progression. She also studies genetic mutations in genes that are critical for epigenome regulation and progression of human cancer.

Highlighted Publications

Contreras JR, Palanichamy JK, Tran TM, Fernando TR, Rodriguez-Malave NI, Goswami N, Arboleda VA, Casero D, Rao DS. MicroRNA-146a modulates B-cell oncogenesis by regulating Egr1. Oncotarget. 2015 May 10;6(13):11023-37.

Borges KS, Arboleda VA, Vilain E. Mutations in the PCNA-binding site of CDKN1C inhibit cell proliferation by impairing the entry into S phase. Cell Div. 2015 Mar 28;10:2. doi: 10.1186/s13008-015-0008-8. eCollection 2015.

Arboleda VA, Lee S. Lymphoma and gout coexisting in the same joint fluid. Blood. 2015 May 14;125(20):3213. No abstract available.

Arboleda VA, Lee H, Parnaik R, Fleming A, Banerjee A, Ferraz-de-Souza B, Delot EC, Rodriguez-Fernandez IA, Braslavsky D, Bergada I, Dell'Angelica EC, Nelson SF, Martinez-Agosto JA, Achermann JC, Vilain E. Mutations in the PCNA-binding domain of CDKN1C cause IMAGe syndrome. Nat Genet. 2012 May 27;44(7):788-92. doi: 10.1038/ng.2275.