Dr. Mario Deng is an internationally recognized leader in heart transplant, mechanical circulatory support and the management of advanced heart failure. His research interests focuson the survival and quality-of-life benefit offered by heart transplantation, mechanical circulatory support and other treatment options. Deng has been a pioneer in translating advances in basic science research into treatments for advanced heart failure, particularly addressing the interactions between the cardiovascular and immune systems.
Deng MC, Elashoff B, Pham MX, Teuteberg JJ, Kfoury AG, Starling RC, Cappola TP, Kao A, Anderson AS, Cotts WG, Ewald GA, Baran DA, Bogaev RC, Shahzad K, Hiller D, Yee J, Valantine HA; for the IMAGE Study Group. Utility of Gene Expression Profiling Score Variability to Predict Clinical Events in Heart Transplant Recipients. Transplantation. 2014 Jan 31. [Epub ahead of print]
Adigopula S, Vivo RP, DePasquale EC, Nsair A, Deng MC. Management of ACCF/AHA Stage C heart failure. Cardiol Clin. 2014 Feb;32(1):73-93, viii. doi: 10.1016/j.ccl.2013.09.012.
Nsair A, Liem DA, Cadeiras M, Cheng RK, Allareddy M, Kwon M, Shemin R, Deng MC. Molecular basis of recovering on mechanical circulatory support. Heart Fail Clin. 2014 Jan;10(1 Suppl):S57-62. doi: 10.1016/j.hfc.2013.08.007.
Menon R, Deng M, Ruenauver K, Queisser A, Offermann A, Boehm D, Vogel W, Scheble V, Fend F, Kristiansen G, Wernert N, Oberbeckmann N, Biskup S, Rubin MA, Shaikhibrahim Z, Perner S. Somatic copy number alterations by whole exome sequencing implicates YWHAZ and PTK2 in castration-resistant prostate cancer. J Pathol. 2013 Sep 23. doi: 10.1002/path.4274. [Epub ahead of print]
Wang D, Fang C, Zong NC, Liem DA, Cadeiras M, Scruggs SB, Yu H, Kim AK, Yang P, Deng M, Lu H, Ping P. Regulation of acetylation restores proteolytic function of diseased myocardium in mouse and human. Mol Cell Proteomics. 2013 Dec;12(12):3793-802. doi: 10.1074/mcp.M113.028332. Epub 2013 Sep 15.