Dr. Sedrak is a nationally recognized physician-scientist focused on improving the health outcomes of patients and survivors of cancer. He is the Director of the Cancer and Aging Program, an interdisciplinary, translational, bench-to-bedside research program that studies the impact of cancer and cancer treatment on fundamental aging processes. The ultimate goal of this research is to develop new strategies to prevent, delay, or mitigate the adverse age-related effects of cancer and cancer treatment.
Ji J, Sun CL, Cohen HJ, Synold T, Muss H, Sedrak MS. Inflammation and Clinical Decline After Adjuvant Chemotherapy in Older Adults with Breast Cancer: Results From the Hurria Older Patients Prospective Study. J Clin Oncol. 2022 Sep 20:JCO2201217. PMID: 36126235.
Sedrak MS*, Magnuson A*, Gross CP, Tew WP, Klepin HD, Wildes TM, Muss HB, Dotan E, Freedman RA, O'Connor T, Dale W, Cohen HJ, Katheria V, Arsenyan A, Levi A, Kim H, Mohile S, Hurria A, Sun CL. Development and Validation of a Risk Tool for Predicting Severe Toxicity in Older Adults Receiving Chemotherapy for Early-Stage Breast Cancer. J Clin Oncol. 2021 Feb 20;39(6):608-618 PMID: 33444080; PMCID: PMC8189621. (*=co-first authors)
Sedrak MS, Freedman RA, Cohen HJ, Muss HB, Jatoi A, Klepin HD, Wildes TM, Le- Rademacher JG, Kimmick GG, Tew WP, George K, Padam S, Liu J, Wong AR, Lynch A, Djulbegovic B, Mohile SG, Dale W. Older adult participation in cancer clinical trials: A systematic review of barriers and interventions. CA Cancer J Clin. 2021 Jan;71(1):78-92. PMID: 33002206; PMCID: PMC7854940.
Sedrak MS, Mohile SG, Sun V, Sun CL, Chen BT, Li D, Wong AR, George K, Padam S, Liu J, Katheria V, Dale W. Barriers to clinical trial enrollment of older adults with cancer: A qualitative study of the perceptions of community and academic oncologists. J Geriatr Oncol. 2020 Mar;11(2):327 334. PMID: 31375399; PMCID: PMC6989372.
Sedrak MS, Myers JS, Small DS, Nachamkin I, Ziemba JB, Murray D, Kurtzman GW, Zhu J, Wang W, Mincarelli D, Danoski D, Wells BP, Berns JS, Brennan PJ, Hanson CW, Dine CJ, Patel MS. Effect of a Price Transparency Intervention in the Electronic Health Record on Clinician Ordering of Inpatient Laboratory Tests: The PRICE Randomized Clinical Trial. JAMA Intern Med. 2017 Jul 1;177(7):939-945. PMID: 28430829; PMCID: PMC5543323.