Yi-Ling Lin, DDS, DMSc

Yi-Ling Lin, DDS, DMSc

Associate Professor, School of Dentistry, Division of Oral Pathology


English, Chinese - Mandarin, Taiwanese


Oral and Maxillofacial pathology



Dana-Farber Cancer Institute, 1999 - 2003
Genetics Institute/Harvard School of Dental Medicine, 1997 - 1999


Veterans General Hospital, Taipei, Taiwan, 1988 - 1989


DMSc, Harvard School of Dental Medicine, 1997
DDS, National Yang-Ming Medical College, Taiwan, 1989


Harvard School of Dental Medicine, 1992 - 1997

Board Certification

Diplomate, American Board of Oral and Maxillofacial Pathology, 1997

Contact Information

Clinical Interests

Oral and Maxillofacial pathology

Scientific Interests

Dr. Yi-Ling Lin's research focuses on transcription regulation during osteoclast differentiation. She is currently studying the relationship between Mitf, a helix-loop-helix lucine zipper transcription factor, and three other transcription factors, c-Fos, NF-kappaB and NFATc1, during RANKL signaling. Her goal is to develop therapeutic strategies to inhibit osteoclast activity for osteolytic diseases such as periodontitis and cancer bone metastasis.

Highlighted Publications

Chen W, Yi JK, Shimane T, Mehrazarin S, Lin YL, Shin KH, Kim RH, Park NH, Kang MK. Grainyhead-like 2 regulates epithelial plasticity and stemness in oral cancer cells. Carcinogenesis. 2016 May;37(5):500-10. doi: 10.1093/carcin/bgw027. Epub 2016 Mar 1.

Yang YH, Buhamrah A, Schneider A, Lin YL, Zhou H, Bugshan A, Basile JR. Semaphorin 4D Promotes Skeletal Metastasis in Breast Cancer. PLoS One. 2016 Feb 24;11(2):e0150151. doi: 10.1371/journal.pone.0150151. eCollection 2016.

Lau C, Kim Y, Chia D, Spielmann N, Eibl G, Elashoff D, Wei F, Lin YL, Moro A, Grogan T, Chiang S, Feinstein E, Schafer C, Farrell J, Wong DT. Role of pancreatic cancer-derived exosomes in salivary biomarker development. J Biol Chem. 2013 Sep 13;288(37):26888-97. doi: 10.1074/jbc.M113.452458. Epub 2013 Jul 23.

Binmadi NO, Yang YH, Zhou H, Proia P, Lin YL, De Paula AM, Guimaraes AL, Poswar FO, Sundararajan D, Basile JR. Plexin-B1 and semaphorin 4D cooperate to promote perineural invasion in a RhoA/ROK-dependent manner. Am J Pathol. 2012 Mar;180(3):1232-42. doi: 10.1016/j.ajpath.2011.12.009. Epub 2012 Jan 15.

Li M, Saghafi N, Freymiller E, Basile JR, Lin YL. Metastatic Merkel cell carcinoma of the oral cavity in a human immunodeficiency virus-positive patient and the detection of Merkel cell polyomavirus. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 May;115(5):e66-71. doi: 10.1016/j.oooo.2012.09.002. Epub 2012 Dec 12.