Zev A. Wainberg, MD

Zev Wainberg, MD, MSc

Professor, Department of Medicine, Hematology/Oncology, Gastrointestinal Oncology Program, UCLA/Santa Monica Cancer Center
Director, Early Phase Clinical Research Support (EPCRS)





Institutional Affiliation

UCLA Medical Center, Santa Monica
Ronald Reagan UCLA Medical Center



Hematology/Oncology, UCLA School of Medicine, 2003 - 2006


Internal Medicine, Montefiore Medical Center Moses Division Hospital, 2000 - 2001


MD, Tel Aviv University Sackler School of Medicine, 2000


Internal Medicine, Montefiore Medical Center Moses Division Hospital, 2001 - 2003

Board Certification

Internal Medicine, American Board of Internal Medicine, 2003

Contact Information

Clinical Interests

Biliary, Cancers Of The Digestive Tract, General Hematology, General Oncology

Scientific Interests

Dr. Zev Wainberg's clinical interests include designing GI (gastroenterology) cancer clinical trials. He is particularly interested in the development and testing of new targeted therapies for the treatment of colon cancer, gastric cancer and esophagus cancer.

Wainberg's laboratory and translational research involves gene expression patterns in a variety of GI cancers and the molecular profiling of these cancers for novel therapies. His research also involves the targeting of GI and prostate cancers with new antibody technologies.

Highlighted Publications

Wainberg ZA, Lin LS, DiCarlo B, Dao KM, Patel R, Park DJ, Wang HJ, Elashoff R, Ryba N, Hecht JR. Phase II trial of modified FOLFOX6 and erlotinib in patients with metastatic or advanced adenocarcinoma of the oesophagus and gastro-oesophageal junction. Br J Cancer. 2011 Sep 6;105(6):760-5. Epub 2011 Aug 2

Tanaka H, Kono E, Tran CP, Miyazaki H, Yamashiro J, Shimomura T, Fazli L, Wada R, Huang J, Vessella RL, An J, Horvath S, Gleave M, Rettig MB, Wainberg ZA, Reiter RE. Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance. Nat Med. 2010 Dec;16(12):1414-20. Epub 2010 Nov 7

Wainberg ZA, Anghel A, Desai AJ, Ayala R, Luo T, Safran B, Fejzo MS, Hecht JR, Slamon DJ, Finn RS. Lapatinib, a dual EGFR and HER2 kinase inhibitor, selectively inhibits HER2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo. Clin Cancer Res. 2010 Mar 1;16(5):1509-19. Epub 2010 Feb 23

Bilchik A, Nissan A, Wainberg Z, Shen P, McCarter M, Protic M, Howard R, Elashoff D, Tyler J, Peoples GE, Stojadinovic A. Surgical quality and nodal ultrastaging is associated with long-term disease-free survival in early colorectal cancer: an analysis of 2 international multicenter prospective trials. Ann Surg. 2010 Sep;252(3):467-74; discussion 474-6.