Let’s develop an innovative cancer immunotherapy together!

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This is a unique opportunity for philanthropic donors to support Dr. Caspian Oliai and Dr. Lili Yang, of the UCLA Health Jonsson Comprehensive Cancer Center, to develop a therapy that can change the field of oncology and be an important step to making chemotherapy a thing of the past. 

Our goal is to engage philanthropists with world-renown UCLA physicians and scientists as the latter works to develop a therapy that has the potential to profoundly improve the lives of local Angelenos and their families whose lives have been changed by cancer.

The immunotherapy CD70-CAR iNKT is an “off-the-shelf” allogeneic cellular product, derived from healthy donors, that leverages a highly purified and polyclonal population of immune cells engineered to identify and eradicate leukemia. 

The preclinical phase of the translational development of CD70-CAR iNKT therapy has been completed. Our research so far has been made possible by grants that were obtained through a highly selective process, that included funding from the California Institute for Regenerative Medicine (CIRM) made possible by Californian voters who overwhelmingly passed proposition 71 to fund stem cell research. 

The next step is to bring our product from the research bench to the patient bedside, through our first clinical trial of CD70-CAR iNKT cell therapy against leukemia. We need philanthropic support to achieve this goal. As a donor to this exciting and important undertaking, you will receive updates and be invited to meet with Dr. Oliai and his team as they make progress in the development of this therapy. Depending on your donation level, you will also be recognized in publications, on presentations, and on UCLA donor rosters, should you wish. This is the opportunity of a lifetime for all of us involved to move a field into the future! We look forward to having you advance our work to help local Angelenos with leukemia, and in the near future leukemia patients throughout the country. Thank you.

Sincerely,

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Dr. Caspian Oliai

 

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