Thomas Vondriska, PhD

The Vondriska lab seeks to understand fundamental chromatin mechanisms that underpin cell growth and cell death.

Rosa-Garrido M, Chapski DJ, Schmitt AD, Kimball TH, Karbassi E, Monte E, Balderas E, Pellegrini A, Shih T-T, Soehalim E, Liem D, Ping P, Galjart NJ, Ren S, Wang Y, Ren B, Vondriska TM. High resolution mapping of chromatin conformation in cardiac myocytes reveals structural r modeling of the epigenome in heart failure. Circulation. 2017. 136:1613-1625 PMID:28802249.

Chapski DJ, Rosa-Garrido M, Hua N, Alber F, Vondriska TM. Spatial principles of chromatin architecture associated with organ-specific gene regulation. Frontiers in Cardiovascular Medicine. 2019. 5:186. PMID: 30697540.

Lazaropoulos MP, Gibb AA, Chapski DJ, Nair AA, Reiter AN, Roy R, Eaton DM, Bedi KC, Margulies KB, Wellen KE, Estarás, Vondriska TM, Elrod JW. Nuclear ATP-citrate lyase regulates chromatin-dependent activation and maintenance of the myofibroblast gene program. Nature Cardiovascular Research. 2024. PMID: 39196175

Arrieta A, Chapski DJ, Reese A, Kimball TH, Song K, Rosa Garrido M, Vondriska TM. Circadian control of histone turnover during cardiac development and growth. J Biol Chem. 2024. PMID: 38830405

Hu S, Chapski DJ, Gehred N, Kimball TK, Gromova T, Flores A, Rowat AC, Chen J, Packard RRS, Olszewski E, Davis J, Rau CD, McKinsey TA, Rosa Garrido M, Vondriska TM. Histone H1.0 couples cellular mechanical behaviors to chromatin structure. Nature Cardiovascular Research. 2024. PMID: 38765203