David Jeffrey Demanes, MD

David (D. Jeffrey) Jeffrey Demanes, MD

Professor, Department of Radiation Oncology, Brachytherapy
Director, High Dose Rate (HDR) Brachytherapy program




Brachytherapy - Radiation Oncology

Institutional Affiliation

Ronald Reagan UCLA Medical Center
UCLA Medical Center, Santa Monica



Radiation Oncology, Long Beach Memorial Medical Center, 1981 - 1981
Internal Medicine, UC San Francisco School of Medicine, 1979 - 1981


Internal Medicine, Kaiser Foundation Hospital, 1974 - 1975


MD, UCLA School of Medicine, 1974


Radiation Oncology, UCLA School of Medicine, 1976 - 1979
Internal Medicine, Veterans Affairs Greater Los Angeles Healthcare System, 1975 - 1976

Board Certifications

Medical Oncology, American Board of Internal Medicine, 1981
Therapeutic Radiology, American Board of Radiology, 1979
Internal Medicine, American Board of Internal Medicine, 1978

Clinical Interests

Brachytherapy, Women's Cancers, Genitourinary Oncology, Thoracic Oncology (Developing)

Scientific Interests

Dr. Jeffrey Demanes' scientific interests are clinical outcome studies for patients treated with brachytherapy, development of brachytherapy technical methods, and innovative applications for brachytherapy. His special area of expertise is high dose rate (HDR) brachytherapy.

Highlighted Publications

Demanes DJ, Martinez AA, Ghilezan M, Hill DR, Schour L, Brandt D, Gustafson G. High-dose-rate monotherapy: safe and effective brachytherapy for patients with localized prostate cancer. Int J Radiat Oncol Biol Phys. 2011 Dec 1;81(5):1286-92. doi: 10.1016/j.ijrobp.2010.10.015. Epub 2011 Feb 9.

Demanes DJ, Brandt D, Schour L, Hill DR. Excellent results from high dose rate brachytherapy and external beam for prostate cancer are not improved by androgen deprivation. Am J Clin Oncol. 2009 Aug;32(4):342-7.

Demanes DJ, Rodriguez RR, Schour L, Brandt D, Altieri G. High-dose-rate intensity-modulated brachytherapy with external beam radiotherapy for prostate cancer: California endocurietherapy's 10-year results. Int J Radiat Oncol Biol Phys. 2005 Apr 1;61(5):1306-16. Review.

Demanes DJ, Samaranayake RP, Cmelak A, Cruz R, Rodriguez RR. Brachytherapy and External Radiation for Carcinoma of the Base of Tongue: Implantation of the Primary Tumor and Cervical Adenopathy. International Journal of Brachytherapy, 2000: 16:211-223.

Demanes DJ, Rodriguez RR, Bendre DD, Ewing TL. High dose rate transperineal interstitial brachytherapy for cervical cancer: high pelvic control and low complication rates. Int J Radiat Oncol Biol Phys. 1999 Aug 1;45(1):105-12.