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Analgesic and Subjective Effects of Terpenes
About
Brief Summary
The purpose of this research is to assess the analgesic and subjective effects of terpenes administered alone and in combination of THC.
Primary Purpose
Study Type
Phase
Eligibility
Gender
Healthy Volunteers
Minimum Age
Maximum Age
Inclusion Criteria:
- Male or non-pregnant female aged 21-55 years
- Report non-medical use of cannabis 2-6 days per week
- Not currently seeking treatment for cannabis use
- Urine test positive for recent cannabis use
- Have a Body Mass Index from 18.5 - 34kg/m2.
- Able to perform all study procedures
- Must be using a contraceptive method (hormonal or barrier methods)
Exclusion Criteria:
- Meeting DSM-V criteria for any substance use disorder other than nicotine, caffeine, or mild CUD
- Report using other illicit drugs in the prior 4 weeks
- If medical history, physical and psychiatric examination, or laboratory tests performed during the screening process revealed any significant illness (e.g., hypertension)
- Current use of medical cannabis, prescription analgesics, or any medications that may affect study outcomes
- Current pain
- History of respiratory illness or current respiratory illness
- History of seizure disorder or current seizure disorder
- Insensitivity to the cold water stimulus of the Cold Pressor Test
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Study Stats
Protocol No.
19-001519
Category
Semel Institute (Psychiatry)
Principal Investigator
Ziva Cooper
Contact
Location
- UCLA Westwood