Autoimmune Protocol Diet Intervention on Proteinuria in IgA Nephropathy Patients
About
This study at UCLA Center for Health Sciences is testing whether the Autoimmune Protocol (AIP) diet can lower protein levels in the urine of people with IgA Nephropathy (IgAN), a common kidney disease that can lead to kidney failure. The AIP diet avoids foods that may cause inflammation (like dairy, grains, and sugar) for 8 weeks, then gradually reintroduces them over 4 months. We're enrolling 30 adults aged 18-65 with IgAN and protein in their urine to try this diet for 6 months. Participants will track their urine protein daily at home, keep a food log, and have monthly lab checkups, with support from a diet expert. The main goal is to see if the diet reduces urine protein by 20% or more, which could slow disease progression and reduce the need for treatments like dialysis. This exploratory study aims to find out if diet changes can help manage IgAN.
Eligibility
Inclusion Criteria:
- Age 18-65
- Diagnosed with IgA Nephropathy (IgAN)
- Active disease with urine protein/creatinine ratio ≥ 1
- Stable ARB or ACE inhibitor for at least 1 month prior
- GFR > 30
- Not on Budesonide 1 month prior or during study
Exclusion Criteria:
- Inability to comply with dietary or follow-up requirements
- Participation in other interventional studies
- Significant comorbidities interfering with study participation -
Join this Trial
- UCLA Manhattan Beach