Open Actively Recruiting

An observational study evaluating viral shedding and development of immune responses in mother-infant pairs affected by COVID-19

About

Brief Summary

The goal of this study is to understand how pregnant women and their newborn babies respond to SARS-CoV-2 infection in pregnancy, the virus responsible for COVID-19. The two main purposes of the study are: 1) to evaluate for the presence of the virus and development of antibodies in pregnant women diagnosed with COVID-19 and their newborn infants over time, and 2) to monitor markers of disease severity in the same blood samples. The research study will last one year. We will collect blood samples from you to check for the presence of antibodies and markers of disease severity at the time of enrollment, at delivery, 6-weeks, 6-months and 12-months. We will collect blood samples from your baby at 24-hours of life (at the hospital, with routine labs), at 6 months, and 12 months. We will also collect nasopharyngeal swabs from you at delivery to detect the presence of virus in your nose, and from your baby within 48 hours of life. We expect you will be in this research study for a total of 4 visits for you and your baby, with each evaluation lasting approximately 30 minutes until 1 year after birth.

Eligibility

  • Currently pregnant
  • Aged 18 or over
  • Diagnosis of COVID-19 during current pregnancy (by nasopharyngeal PCR test)
  • Agree to the scheduled blood draws and clinical appointments as outlined above
  • Receiving care from a UCLA-affiliated OB/GYN in Westwood or Santa Monica OR planning to deliver at UCLA Hospital in Westwood or Santa Monica

Join this Trial

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Study Stats
Protocol No.
20-000569
Category
Pediatrics
Other
Contact
Tara Kerin
Location
  • UCLA Westwood