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Use of Acthar in Rheumatoid Arthritis (RA) Related Flares

About

Brief Summary

This is a Rheumatoid Arthritis (RA) study. The purpose of this research study is to determine in RA flare, whether musculoskeletal ultrasound (MSUS) inflammatory scores and/or disease activity scores improve with Acthar treatment.

Primary Purpose
Diagnostic
Study Type
Interventional
Phase
Phase IV

Eligibility

Gender
All
Healthy Volunteers
No
Minimum Age
18 Years
Maximum Age
N/A

Inclusion Criteria:

  • Patient must meet 1987 ACR criteria
  • Age > 18 years of age
  • Baseline DAS28/Erythrocyte Sedimentation Rate (ESR) >=3.2
  • Stable concomitant Disease Modifying Anti-Rheumatic Drugs (DMARDs)
  • Stable prednisone <10mg or equivalent
  • Power Doppler score of >=10

Exclusion Criteria:

  • Prior treatment with Acthar in the past 2mos
  • Meet one of the above RA flare requirements
  • Subjects who have received live or live attenuated vaccines within 6 weeks prior to the first dose of study drug (or the zoster vaccine)

Join this Trial

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Study Stats
Protocol No.
15-001199
Category
Rheumatology
Contact
Mia Vasquez-Gutierrez
Location
  • UCLA Westwood
For Providers
NCT No.
NCT02541955
For detailed technical eligibility, visit ClinicalTrials.gov.