Use of Acthar in Rheumatoid Arthritis (RA) Related Flares

About

Brief Summary

This is a Rheumatoid Arthritis (RA) study. The purpose of this research study is to determine in RA flare, whether musculoskeletal ultrasound (MSUS) inflammatory scores and/or disease activity scores improve with Acthar treatment.

Primary Purpose

Diagnostic

Study Type

Interventional

Phase

Phase 4

Eligibility

Gender

All

Healthy Volunteers

No

Minimum Age

18 Years

Maximum Age

N/A

Inclusion Criteria:

Patient must meet 1987 ACR criteria
Age > 18 years of age
Baseline DAS28/Erythrocyte Sedimentation Rate (ESR) >=3.2
Stable concomitant Disease Modifying Anti-Rheumatic Drugs (DMARDs)
Stable prednisone <10mg or equivalent
Power Doppler score of >=10

Exclusion Criteria:

Prior treatment with Acthar in the past 2mos
Meet one of the above RA flare requirements
Subjects who have received live or live attenuated vaccines within 6 weeks prior to the first dose of study drug (or the zoster vaccine)

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