Dr. Ruan has a wide interest in medical imaging, system modeling, optimization, informatics, and machine learning. With a PhD in Electrical Engineering and MS in Mathematics, Dr. Ruan is particularly interested in understanding the mathematics and physics in diagnostic radiology and radiation oncology. She has extensive knowledge and experience with the modeling, characterization, and solving the inverse problems for various medical imaging systems. Her research also covers longitudinal analysis and hybrid control based on heterogeneous data. As director of informatics, Dr. Ruan is in charge of the design and management of clinical and research registry, system integration and interface, and big data analytics and business intelligence solutions. Dr. Ruan is on the Board of Associate Editors for the Medical Physics Journal and a member of the Medical Physic Dataset Article Subcommittee. She is also affiliated with Bioengineering Department and the CAMPEP-accredited Physics and Biology in Medicine Interdisciplinary Graduate Program.