Alison Chu

Alison Chu, MD

Neonatology

About

Dr. Alison Chu has been a UCLA faculty member since 2013, where she supervises care in the inpatient neonatal ICUs at UCLA Mattel Children's Hospital and UCLA Medical Center Santa Monica. She is board certified in both Pediatrics and Perinatal-Neonatal Medicine.

Dr. Chu earned her bachelor's degree and her medical degree at Northwestern University in Illinois. She completed her pediatric residency and neonatology fellowship at the University of Chicago. During her fellowship, Dr. Chu conducted research in the laboratory of Dr. David Gozal, studying the developmental programming of cardiovascular disease in a mouse model of postnatal hypoxia exposure.

Dr. Chu's research interests are centered around the mechanisms underlying vascular diseases of the neonate. She has received funding from the American Heart Association as well as the NICHD, amongst others, to study placental vascular insufficiency that underlies intrauterine growth restriction. More recently, her interests have extended to understanding the vascular disease seen in retinopathy of prematurity, both by using basic research animal models of oxygen-induced retinopathy as well as by using advanced imaging techniques in human neonates. She has published a number of peer-reviewed research articles, review articles, a book chapter, and a neonatology textbook.

Education

Medical Board Certifications

Neonatal-Perinatal Medicine, American Board of Pediatrics, 2014
Pediatrics, American Board of Pediatrics, 2010

Fellowship

University of Chicago Hospitals, 2013

Residency

University of Chicago Hospitals, 2010

Internship

University of Chicago Hospitals, 2008

Degree

Northwestern University GME, MD, 2007

Hospital Affiliations

Research

Publications

  1. Chang CC*, Chu A*, Meyer S, Ding Y, Sun MM, Abiri P, Baek KI, Gudapati V, Ding X, Guihard P, Guihard P, Bostrom KI, Li S, Gordon LK, Zheng JJ, Hsiai TK. Three-dimensional imaging coupled with topological quantification uncovers retinal vascular plexuses undergoing obliteration. Theranostics. 2021 Jan 1;11(3):1162-1175. PMID 33391527 (*co-first authors)
  2. Chu A, Dhindsa Y, Altendahl M, Tsui I. Prenatal intrauterine growth restriction and risk of retinopathy of prematurity. Scientific Reports. Oct 2020;10(1):17591. PMID: 33067506.
  3. Douglass M, Strobel KM, Richley M, Mok T, de St. Maurice A, Fajardo V, Young A, Rao R, Lee L, Benharash P, Chu A, Afshar Y. Maternal-Neonatal Dyad outcomes of maternal COVID-19 requiring extracorporeal membrane support: a case series. Am J Perinatol. 2021 Janl38(1):82-87. PMID: 33069171.
  4. Wong BM, Chu A, Tsui I. Regression of cystoid macular edema three weeks after laser for retinopathy of prematurity. Ophthalmic Surg Lasers Imaging Retina. 2020 Aug 1;51(8):472-475. PMID 32818280 (cover art)
  5. Langston S, Pithia N, Shin MS, Garg M, de St. Maurice A, Chu A. Lack of utility of tracheal aspirates in the management of suspected neonatal pneumonia in intubated neonates. Infect Control Hosp Epidemiol. Mar 2020;1-6. PMID: 32209148.
  6. Kothari N, Chu A, Huang M, Lin F, Lin BR, Manoharan N, Gui W, Huang A, Tsui I. Arm-mounted optical coherence tomography angiography in extremely low birth weight neonates with retinopathy of prematurity. Am J Ophthalmol Case Rep. Feb 2020; 18: 100624. PMID 32154434.
  7. Wadehra M, Sun M, Casero D, Chen M, Aguirre B, Parikh S, Matynia A, Gordon L, Chu A. Epithelial membrane protein-2 promotes VEGF signaling and pathological neovascular growth in murine hyperoxia-induced retinopathy. Invest Ophthalmol Vis Sci. 2020 Feb;61(2):3. PMID: 32031575.
  8. Sangkhae V, Fisher AL, Wong S, Koenig MD, Tussing-Humphreys L, Chu A, Lelíc M, Ganz T, Nemeth E. Effects of maternal iron status on placental and fetal iron homeostasis. J Clin Invest. 2020 Feb;130(2):625-640. PMID 31661462.
  9. Chu A, Najafzadeh P, Sullivan P, Janzen C, Mah V, Wadehra M. Aldehyde dehydrogenase isoforms are differentially expressed in inflammatory macrophage and extravillous trophoblast cell populations in term human placentas affected by intrauterine growth restriction. Placenta. 2019 Jun;81:9-17. PMID: 31138432.
  10. Chu A, Casero D, Thamotharan S, Wadehra M, Cosi A, Devaskar SU. The placental transcriptome in late gestational hypoxia resulting in murine intrauterine growth restriction parallels increased risk of adult cardiometabolic disease." Scientific Reports. 2019 Feb;9:1243. PMID: 30718791.

Awards

  • Top Doctors, Los Angeles Magazine, 2021
  • Super Doctors® Southern California Rising Stars 2021
  • Top Doctors, Los Angeles Magazine, 2020
  • Super Doctors® Southern California Rising Stars 2019
  • 2019 WSPR Mead Johnson Nutrition Junior Faculty Travel Award January 2019
  • Western Society for Pediatric Research, Carmel, CA
  • Abbott Nutrition Award in Research by a Young Investigator January 2018
  • Western Society for Pediatric Research, Carmel, CA